Genome Editing in Drug Discovery

Book Genome Editing in Drug Discovery Cover

Download or read online Genome Editing in Drug Discovery PDF book by Marcello Maresca in ePUB, PDF or Kindle eBooks. Published by John Wiley & Sons in 15 March 2022 the book become immediate popular and critical acclaim in Science books with total hardcover page 352. Click Download Book button to get book file. Read some info about this book below.

  • Author : Marcello Maresca
  • Publisher : John Wiley & Sons
  • Release : 15 March 2022
  • ISBN : 9781119671398
  • Page : 352 pages
  • Language : English
  • Total View : 6173 Views
  • File Size : 41,8 Mb

Genome Editing in Drug Discovery Book PDF summary

GENOME EDITING IN DRUG DISCOVERY A practical guide for researchers and professionals applying genome editing techniques to drug discovery In Genome Editing in Drug Discovery, a team of distinguished biologists delivers a comprehensive exploration of genome editing in the drug discovery process, with coverage of the technology’s history, current issues and techniques, and future perspectives and research directions. The book discusses techniques for disease modeling, target identification with CRISPR, safety studies, therapeutic editing, and intellectual property issues. The safety and efficacy of drugs and new target discovery, as well as next-generation therapeutics are also presented. Offering practical suggestions for practitioners and academicians involved in drug discovery, Genome Editing in Drug Discovery is a fulsome treatment of a technology that has become part of nearly every early step in the drug discovery pipeline. Selected contributions also include: A thorough introduction to the applications of CRISPRi and CRISPRa in drug discovery Comprehensive explorations of genome-editing applications in stem cell engineering and regenerative medicine Practical discussions of the safety aspects of genome editing with respect to immunogenicity and the specificity of CRISPR-Cas9 gene editing In-depth examinations of critical socio-economic and bioethical challenges in the CRISPR-Cas9 patent landscape Perfect for academic researchers and professionals in the biotech and pharmaceutical industries, Genome Editing in Drug Discovery will also earn a place in the libraries of medicinal chemists, biochemists, and molecular biologists.

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