Innovative Approaches in Drug Discovery

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  • Publisher : Academic Press
  • Release : 03 October 2016
  • ISBN : 9780128018224
  • Page : 480 pages
  • Rating : 4.5/5 from 103 voters

Innovative Approaches in Drug Discovery Book PDF summary

Despite considerable technological advances, the pharmaceutical industry is experiencing a severe innovation deficit, especially in the discovery of new drugs. Innovative Approaches in Drug Discovery: Ethnopharmacology, Systems Biology and Holistic Targeting provides a critical review and analysis of health, disease and medicine, and explores possible reasons behind the present crisis in drug discovery. The authors illustrate the benefits of systems biology and pharmacogenomics approaches, and advocate the expansion from disease-centric discovery to person-centric therapeutics involving holistic, multi-target, whole systems approaches. This book lays a path for reigniting pharmaceutical innovation through a disciplined reemergence of pharmacognosy, embracing open innovation models and collaborative, trusted public-private partnerships. With unprecedented advances made in the development of biomedically-relevant tools and technologies, the need is great and the time is now for a renewed commitment towards expanding the repertoire of medicines. By incorporating real-life examples and state-of-the-art reviews, this book provides valuable insights into the discovery and development strategies for professionals, academicians, and students in the pharmaceutical sciences. Analyzes the reasons behind historical drug failures to provide valuable insights on lessons learned Uses current scientific research to promote learning from traditional knowledge systems and through the integration of traditional and western medicines Discusses advances in technologies and systems biology to support the transition from formulation discovery to therapeutic discovery

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Innovative Approaches in Drug Discovery

Innovative Approaches in Drug Discovery
  • Author : Bhushan Patwardhan,Rathnam Chaguturu
  • Publisher : Academic Press
  • Release Date : 2016-10-03
  • ISBN : 9780128018224
DOWNLOAD BOOKInnovative Approaches in Drug Discovery

Despite considerable technological advances, the pharmaceutical industry is experiencing a severe innovation deficit, especially in the discovery of new drugs. Innovative Approaches in Drug Discovery: Ethnopharmacology, Systems Biology and Holistic Targeting provides a critical review and analysis of health, disease and medicine, and explores possible reasons behind the present crisis in drug discovery. The authors illustrate the benefits of systems biology and pharmacogenomics approaches, and advocate the expansion from disease-centric discovery to person-centric therapeutics involving holistic, multi-target, whole systems approaches.

New Approaches to Drug Discovery

New Approaches to Drug Discovery
  • Author : Ulrich Nielsch,Ulrike Fuhrmann,Stefan Jaroch
  • Publisher : Springer
  • Release Date : 2016-04-08
  • ISBN : 3319289128
DOWNLOAD BOOKNew Approaches to Drug Discovery

This volume gives an overview of state of the art technologies and future developments in the field of preclinical pharmaceutical research. A balanced mix of experts from academia and industry give insight in selected new developments in the drug discovery pathway. The topics cover the different parts of the drug discovery process, starting with new developments in the target identification and validation area. The lead generation part as a next step focuses on the requirements and technologies to identify new

Innovative Methods for Rare Disease Drug Development

Innovative Methods for Rare Disease Drug Development
  • Author : Shein-Chung Chow
  • Publisher : CRC Press
  • Release Date : 2020-11-11
  • ISBN : 9781000208337
DOWNLOAD BOOKInnovative Methods for Rare Disease Drug Development

In the United States, a rare disease is defined by the Orphan Drug Act as a disorder or condition that affects fewer than 200,000 persons. For the approval of "orphan" drug products for rare diseases, the traditional approach of power analysis for sample size calculation is not feasible because there are only limited number of subjects available for clinical trials. In this case, innovative approaches are needed for providing substantial evidence meeting the same standards for statistical assurance as drugs used

Drug Discovery and Development, Volume 1

Drug Discovery and Development, Volume 1
  • Author : Mukund S. Chorghade
  • Publisher : Wiley-Interscience
  • Release Date : 2006-06-16
  • ISBN : 0471398489
DOWNLOAD BOOKDrug Discovery and Development, Volume 1

From first principles to real-world applications -- here is the first comprehensive guide to drug discovery and development Modern drug discovery and development require the collaborative efforts of specialists in a broadarray of scientific, technical, and business disciplines--from biochemistry to molecular biology, organic chemistry to medicinal chemistry, pharmacology to marketing. Yet surprisingly, until now, there were no authoritative references offering a complete, fully integrated picture of the process. The only comprehensive guide of its kind, this groundbreaking two-volume resource provides

Innovative Approaches in Drug Research

Innovative Approaches in Drug Research
  • Author : A. F. Harms
  • Publisher : Elsevier Publishing Company
  • Release Date : 1986
  • ISBN : UOM:39015011452201
DOWNLOAD BOOKInnovative Approaches in Drug Research

New Approaches to Drug Discovery

New Approaches to Drug Discovery
  • Author : Ulrich Nielsch,Ulrike Fuhrmann,Stefan Jaroch
  • Publisher : Springer
  • Release Date : 2016-03-30
  • ISBN : 9783319289144
DOWNLOAD BOOKNew Approaches to Drug Discovery

This volume gives an overview of state of the art technologies and future developments in the field of preclinical pharmaceutical research. A balanced mix of experts from academia and industry give insight in selected new developments in the drug discovery pathway. The topics cover the different parts of the drug discovery process, starting with new developments in the target identification and validation area. The lead generation part as a next step focuses on the requirements and technologies to identify new

Drug Repurposing

Drug Repurposing
  • Author : Farid A. Badria
  • Publisher : BoD – Books on Demand
  • Release Date : 2020-12-02
  • ISBN : 9781839685200
DOWNLOAD BOOKDrug Repurposing

Drug repurposing or drug repositioning is a new approach to presenting new indications for common commercial and clinically approved existing drugs. For example, chloroquine, an old antimalarial drug, showed promising results for treating COVID-19, interfering with MDR in several types of cancer, and chemosensitizing human leukemic cells.This book focuses on the hypothesis, risk/benefits, and economic impacts of drug repurposing on drug discovery in dermatology, infectious diseases, neurological disorders, cancer, and orphan diseases. It brings together up-to-date research to

Modern CNS Drug Discovery

Modern CNS Drug Discovery
  • Author : Rudy Schreiber
  • Publisher : Springer Nature
  • Release Date : 2021-06-17
  • ISBN : 9783030623517
DOWNLOAD BOOKModern CNS Drug Discovery

This textbook provides a comprehensive overview of the currently used concepts, approaches and technologies in the discovery and development of new treatments for the full spectrum of disorders of the central nervous system. It guides the reader through all essential steps, from finding an innovative idea, to the registration of a new drug. Divided into four sections, the book starts by presenting a broad perspective on current approaches in central nervous system (CNS) drug discovery. The second section addresses the