Developmental and Fetal Origins of Differences in Monozygotic Twins

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  • Publisher : Academic Press
  • Release : 15 May 2020
  • ISBN : 9780128203071
  • Page : 386 pages
  • Rating : 4.5/5 from 103 voters

Developmental and Fetal Origins of Differences in Monozygotic Twins Book PDF summary

Developmental and Fetal Origins of Differences in Monozygotic Twins: From Genetics to Environmental Factors examines the major causes of discordance in monozygotic twins, from genetic, to environmental influences, including discussions on the genetic, epigenetic, fetal and environmental factors. Twin differences discussed include malformations, deformations and disruptions secondary to inequitable division of the early embryo, chromosome and single gene mosaicism, Nonrandom X chromosome inactivation, mitochondrial heteroplasmy, epigenetic variation, and variable and inequitable blood supply, among other influences. Differences in hemoglobin levels, placentation and amniotic fluid are also examined, while full color images illustrate discordant anomalies and twin differences throughout. Examines the major causes of discordance in monozygotic twins and their relevance for future studies and clinical management Discusses NIPT in MZ twins, twin imaging during fetal development, blood tests and forensic analysis Features contributions from international experts in twin genetics and developmental biology

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Developmental and Fetal Origins of Differences in Monozygotic Twins

Developmental and Fetal Origins of Differences in Monozygotic Twins
  • Author : Alexandra Matias,Isaac Blickstein
  • Publisher : Academic Press
  • Release Date : 2020-05-15
  • ISBN : 9780128203071
DOWNLOAD BOOKDevelopmental and Fetal Origins of Differences in Monozygotic Twins

Developmental and Fetal Origins of Differences in Monozygotic Twins: From Genetics to Environmental Factors examines the major causes of discordance in monozygotic twins, from genetic, to environmental influences, including discussions on the genetic, epigenetic, fetal and environmental factors. Twin differences discussed include malformations, deformations and disruptions secondary to inequitable division of the early embryo, chromosome and single gene mosaicism, Nonrandom X chromosome inactivation, mitochondrial heteroplasmy, epigenetic variation, and variable and inequitable blood supply, among other influences. Differences in hemoglobin levels,

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  • Publisher : Academic Press
  • Release Date : 2021-08-27
  • ISBN : 9780128243268
DOWNLOAD BOOKMedical Epigenetics

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  • ISBN : 9783030050757
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  • Publisher : National Academies Press
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It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be

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In Deliberately Divided, Nancy Segal revisits a controversial study that tracked the development of separated twins and triplets. None of the adoptive parents were told that they were raising a multiple birth baby. The truth was shocking for these parents and twins, many of whom have shared their unimaginable stories for the first time.

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The book Gamete and Embryo-fetal Origins of Adult Diseases introduces various diseases resulting from the abnormal gametogenesis and embryo development, which manifests as growth retardation, birth defects, or increased susceptibility to chronic metabolic diseases such as diabetes, cardiovascular disease and cancer in childhood and adult life, even fertility disorders and the risk of transgenerational transmission. Six common kinds of these diseases are discussed in separate chapters. The authors explore the connections between these diseases and epigenetic reprogramming, rapid cell differentiation

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  • Publisher : National Academies Press
  • Release Date : 2015-07-23
  • ISBN : 9780309324885
DOWNLOAD BOOKTransforming the Workforce for Children Birth Through Age 8

Children are already learning at birth, and they develop and learn at a rapid pace in their early years. This provides a critical foundation for lifelong progress, and the adults who provide for the care and the education of young children bear a great responsibility for their health, development, and learning. Despite the fact that they share the same objective - to nurture young children and secure their future success - the various practitioners who contribute to the care and

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  • Publisher : National Academies Press
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  • Publisher : Springer
  • Release Date : 2017-03-15
  • ISBN : 9789811032332
DOWNLOAD BOOKRUNX Proteins in Development and Cancer

This volume provides the reader with an overview of the diverse functions of the RUNX family of genes. As highlighted in the introduction and several of the 29 chapters, humans and other mammals have three RUNX genes that are known to play specific roles in blood, bone and neuronal development. However, their evolutionary history has recently been traced back to unicellular organisms and their involvement in many well-known signaling pathways (Wnt, TGFb, Notch, Hippo) is indicative of a more general function

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  • Release Date : 2009-04-02
  • ISBN : 9780191575228
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Family-based studies, including intergenerational, sibling, and twin studies, are increasingly being used to explore life course epidemiology. However, there are issues relating to study design and the statistical analysis of family-based studies that are still not well understood, and comprehending the underlying assumptions of these studies and drawing the inferences from them can be complex. This book provides the knowledge and skills required to design, analyse, and correctly interpret family-based studies. It explains what these studies can tell us about

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  • Release Date : 2015-05-18
  • ISBN : 9781447166788
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Finch and Kirkwood are two of the leaders of biological gerontology. This book establishes the role of chance variations in affecting the process of ageing in individuals. All the relevant animal and human data are collected and analysed, to establish the relative roles of genes and chance in the ageing process. This is a new theoretical approach to understanding ageing, which will be of widespread interest to gerontologists and developmental and cellular biologists. There are obvious applications of this perspective