Antifungal Compounds Discovery

• Author : Marina Sokovic,Konstantinos Liaras
• Publisher : Elsevier
• Release Date : 2020-09-18
• ISBN : 9780128158258

Fungi are both the cause of many major health problems and an incredible source of compounds for developing new medicinal treatments, and with the increasing emergence of multidrug resistance, the need for new antimicrobial agents is greater than ever. Antifungal Compounds Discovery provides researchers with a detailed study of both natural and synthetic compounds that can be effective against a variety of fungal species, supporting and encouraging the design of innovative, potent new drug candidates for the treatment of fungal

• Author : Malcolm R. Siegel,Hugh Delane Sisler
• Publisher : Unknown
• Release Date : 1977-01-01
• ISBN : 0824765575

V. 1- Discovery, developments, and uses; v. 2 - Interactions in biological and ecological systems.

• Author : Awanish Kumar
• Publisher : Academic Press
• Release Date : 2016-09-12
• ISBN : 9780128113127

Anticandidal Agents provides the latest information on candida drug resistance and its remedial implications. In this compilation, users will find a comprehensive view on overcoming resistance in anticandidal drugs, along with information on novel molecules. Candida albicans is an opportunistic pathogenic fungus responsible for life threating invasive and nosocomial infections across the globe. Candidiasis is a major cause of morbidity among immunocompromised patients. Infections caused by non-albicans candida like C. glabrata, C. parapsilosis, and C. tropicalis have also imposed a

• Author : Sunil K. Deshmukh,J. K. Misra,Jalpa P. Tewari,Tamas Papp
• Publisher : CRC Press
• Release Date : 2018-12-20
• ISBN : 9781315360003

The book deals with the application of fungi and the strategic management of some plant pathogens. It covers fungal bioactive metabolites, with emphasis on those secondary metabolites that are produced by various endophytes, their pharmaceutical and agricultural uses, regulation of the metabolites, mycotoxins, nutritional value of mushrooms, prospecting of thermophilic and wood-rotting fungi, and fungi as myconano factories. Strategies for the management of some plant pathogenic fungi of rice and soybean have also been dealt with. Updated information for all

• Author : Chaminda Jayampath Seneviratne,Edvaldo Antonio Ribeiro Rosa
• Publisher : Frontiers Media SA
• Release Date : 2016-09-13
• ISBN : 9782889199501

Fungal infections such as candidoses can range from superficial mucous membrane infection to life-threatening systemic mycoses. Candida infections are a significant clinical problem globally due to rapid rise in compromised host populations including HIV/AIDS, organ transplant recipients and patients on chemotherapy. In addition, sharp increase in aging populations which are susceptible to fungal infections is expected in next few decades. Antifungal drugs are relatively difficult to develop compared to the antibacterial drugs owing to the eukaryotic nature of the

• Author : Iqbal Ahmad,Mohammad Owais,Mohammed Shahid,Farrukh Aqil
• Publisher : Springer Science & Business Media
• Release Date : 2010-08-03
• ISBN : 9783642121739

Fungi are eukaryotic microorganisms that are closely related to humans at cellular level. Human fungal pathogens belong to various classes of fungi, mainly zygo- cetes, ascomycetes, basidiomycetes, and deuteromycetes. In recent years, fungal infections have dramatically increased as a result of improved diagnosis, high frequency of catheterization, instrumentation, etc. However, the main cause remains the increasing number of immunosuppressed patients, mostly because of HIV infection and indiscriminate usage of antineoplastic and immunosuppressive agents, broad-spectrum antibiotics and prosthetic devices, and grafts

• Author : Mahmoud A. Ghannoum, PhD, EMBA,Mahmoud A. Ghannoum,John R. Perfect,John R. Perfect, MD
• Publisher : CRC Press
• Release Date : 2016-04-19
• ISBN : 9780849387869

A concise one-stop-practical reference for the various physicians dealing with fungal infections, Antifungal Therapy appeals to infectious disease physicians, transplant surgeons, dermatologists, and intensivists, as well as basic scientists and pharmaceutical company researchers interested in the state of antifungal therapy. This book provides a comprehensive, up-to-date overview of the pertinent issues pertaining to antifungal treatment. Divided into four interrelated sections for a cohesive discussion covers: history of antifungals from the discovery of the polyenes to the echinocandins antifungal susceptibility methods

• Author : G. K. Dixon,Leonard G. Copping,Derek W. Hollomon
• Publisher : Bios Scientific Pub Limited
• Release Date : 1995
• ISBN : UCSC:32106012733215

Explores how new molecular technologies are interfacing with chemistry and biology in the search for new fungicide targets.

• Author : Ruth Ashbee,Elaine M. Bignell
• Publisher : Springer Science & Business Media
• Release Date : 2009-10-27
• ISBN : 3642031501

Mycological studies of yeasts are entering a new phase, with the sequencing of multiple fungal genomes informing our understanding of their ability to cause disease and interact with the host. At the same time, the ongoing use of traditional methods in many clinical mycology laboratories continues to provide information for the diagnosis and treatment of patients. This volume reviews various aspects of pathogenic yeasts and what is known about their molecular and cellular biology and virulence, in addition to looking

• Author : Bradley Mark Tebbets
• Publisher : Unknown
• Release Date : 2012
• ISBN : OCLC:822841247

• Author : George Tegos,Eleftherios Mylonakis
• Publisher : CABI
• Release Date : 2012
• ISBN : 9781845939434

Resistance is on the rise among a variety of human pathogenic microorganisms associated with common and potentially life-threatening infections, including penicillin-resistant Streptococcus pneumonia and Methicillin-resistant Staphylococcus aureus (MRSA). There is increasing demand to approach the threat of multidrug resistance incorporating novel multidisciplinary methodologies and technological platforms. This book documents the latest research, covering current and promising activities in four key areas: computational chemistry and chemoinformatics, High Throughput Screening (HTS), non-vertebrate model hosts and light and nano-based technologies. It is essential

• Author : Kevin N. Sorensen
• Publisher : Unknown
• Release Date : 1997
• ISBN : OCLC:43961652

• Author : Jean-Paul Latgé
• Publisher : Springer Nature
• Release Date : 2020-08-12
• ISBN : 9783030499280

This book illustrates, that the fungal cell wall is critical for the biology and ecology of all fungi and especially for human fungal pathogens. Readers will learn, that the composition of the fungal cell wall is a unique structure, which cannot be found in the human host. Consequently, the chapters outline, how the immune systems of both animals and humans have evolved to recognize conserved and unique elements of the fungal cell wall. As an application example, the authors also

• Author : Kalyani Dhusia,Kalpana Raja,Pramod Ramteke
• Publisher : Springer Nature
• Release Date : 2021-02-08
• ISBN : 9783030530778

In the past few decades, it has been realized through research that fungal siderophores epitomize the uptake of iron as well as other essential elements like zinc, magnesium, copper, nickel and arsenic. Understanding the chemical structures of different fungal siderophores and the membrane receptors involved in uptake of mineral ions has opened new areas for research. In this edited volume, recent research is presented on fungal siderophores in one comprehensive volume to provide researchers a strong base for future research.

• Author : Muhammad Imran,Muhammad Asim Farid,Muhammad Adnan Asghar
• Publisher : LAP Lambert Academic Publishing
• Release Date : 2015-06-29
• ISBN : 3659750581

Drug discovery is a vast area of research due to increase in bacterial and fungal resistance against available drugs. This book will give the basic concepts of Schiff-Mannich Base derivatives of Benzimidazole, Metal complexes and their application in the field of drug discovery. It will also provide the basic mechanistic study as well as the knowledge about characterization techniques which will be helpful for young students and researchers to have a deep insight about Antibacterial and Antifungal agents.