Validamycin and Its Derivatives

Book Validamycin and Its Derivatives Cover

Download or read online Validamycin and Its Derivatives PDF book by Xiaolong Chen in ePUB, PDF or Kindle eBooks. Published by Elsevier in 31 March 2017 the book become immediate popular and critical acclaim in Science books with total hardcover page 340. Click Download Book button to get book file. Read some info about this book below.

  • Author : Xiaolong Chen
  • Publisher : Elsevier
  • Release : 31 March 2017
  • ISBN : 9780081011133
  • Page : 340 pages
  • Language : English
  • Total View : 348 Views
  • File Size : 42,5 Mb

Validamycin and Its Derivatives Book PDF summary

Validamycin and Its Derivatives: Discovery, Chemical Synthesis and Biological Activity presents, for the first time, a complete review of the underlying chemistry, synthesis, behavior and application of these compounds. Beginning with an introduction to validamycin, the book then outlines the key elements of its discovery and production, including details of its structures, isolation, analysis, and issues relating to its large scale production. Biological activities are then explored in more detail, followed by details of biosynthesis. Further to this, the chemical synthesis of validamycin and its intermediates, including valienamine, validamine, valiolamine, and validoxylamines is reviewed, before preparation of these derivatives and their biological activities are explored. Finally, the book concludes with a discussion of the economic aspects of working with validamycin and its potential in future applications and trends. With its detailed chemical coverage from a team of expert authors, this detailed guide can be applied to the large-scale industrial production of antibiotics and the adaptation of bioactive agents, from agricultural, to novel pharmaceutical applications. Offers complete coverage of validamycin chemistry from a highly experienced team of authors Encourages the discovery of further novel drugs based on validamycin derivatives Presents an interesting model for establishing new pharmaceutical leads from agricultural sources Includes coverage of the total chemical synthesis of validamycin and its intermediates, including valienamine, validamine, valiolamine and validoxylamines

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