The Chemistry and Biology of Nitroxyl HNO

Book The Chemistry and Biology of Nitroxyl  HNO  Cover

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  • Publisher : Elsevier
  • Release : 01 September 2016
  • ISBN : 9780128011645
  • Page : 424 pages
  • Rating : 4.5/5 from 103 voters

The Chemistry and Biology of Nitroxyl HNO Book PDF summary

The Chemistry and Biology of Nitroxyl (HNO) provides first-of-its-kind coverage of the intriguing biologically active molecule called nitroxyl, or azanone per IUPAC nomenclature, which has been traditionally elusive due to its intrinsically high reactivity. This useful resource provides the scientific basis to understand the chemistry, biology, and technical aspects needed to deal with HNO. Building on two decades of nitric oxide and nitroxyl research, the editors and authors have created an indispensable guide for investigators across a wide variety of areas of chemistry (inorganic, organic, organometallic, biochemistry, physical, and analytical); biology (molecular, cellular, physiological, and enzymology); pharmacy; and medicine. This book begins by exploring the unique molecule’s structure and reactivity, including important reactions with small molecules, thiols, porphyrins, and key proteins, before discussing chemical and biological sources of nitroxyl. Advanced chapters discuss methods for both trapping and detecting nitroxyl by spectroscopy, electrochemistry, and fluorescent inorganic cellular probing. Expanding on the compound’s foundational chemistry, this book then explores its molecular physiology to offer insight into its biological implications, pharmacological effects, and practical issues. Presents the first book on HNO (nitroxyl or azanone), an increasingly important molecule in biochemistry and pharmaceutical research Provides a valuable coverage of HNO’s chemical structure and significant reactions, including practical guidance on working with this highly reactive molecule Contains high quality content from recognized experts in both industry and academia

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The Chemistry and Biology of Nitroxyl (HNO)

The Chemistry and Biology of Nitroxyl (HNO)
  • Author : Fabio Doctorovich,Patrick J. Farmer,Marcelo A. Marti
  • Publisher : Elsevier
  • Release Date : 2016-09-01
  • ISBN : 9780128011645
DOWNLOAD BOOKThe Chemistry and Biology of Nitroxyl (HNO)

The Chemistry and Biology of Nitroxyl (HNO) provides first-of-its-kind coverage of the intriguing biologically active molecule called nitroxyl, or azanone per IUPAC nomenclature, which has been traditionally elusive due to its intrinsically high reactivity. This useful resource provides the scientific basis to understand the chemistry, biology, and technical aspects needed to deal with HNO. Building on two decades of nitric oxide and nitroxyl research, the editors and authors have created an indispensable guide for investigators across a wide variety of

Free Nitroxyl Radicals

Free Nitroxyl Radicals
  • Author : E. Rozantsev
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-12-14
  • ISBN : 9781475707106
DOWNLOAD BOOKFree Nitroxyl Radicals

In the short time since the first nitroxyl radical was obtained in 1959, a new branch of chemical science has arisen and taken shape-the chemistry of stable nitroxyl radicals. The present book was written by E. G. Rozantsev, one of the pioneers in this field and a prominent specialist on stable radicals at the Division of Chemical and Biological Processes of the Institute of Chemical Physics, Academy of Sciences of the USSR. His numerous papers have contributed greatly to the present

Nitrosation Reactions and the Chemistry of Nitric Oxide

Nitrosation Reactions and the Chemistry of Nitric Oxide
  • Author : D.L.H. Williams
  • Publisher : Elsevier
  • Release Date : 2004-12-16
  • ISBN : 0080473601
DOWNLOAD BOOKNitrosation Reactions and the Chemistry of Nitric Oxide

Since 1988, there has been much literature published on the chemistry of nitric oxide, particularly in the field of S-nitrosation and the chemistry of S-nitroso compounds. Written by a chemist for the chemistry community, this book provides an update of the chemistry of nitrosation reactions, dealing with both the synthetic and mechanistic aspects of these reactions. It also looks at the chemistry of nitric oxide in relation to the amazing biological properties of this simple diatomic molecule, which were unknown until

Synthetic Explorations in the Pursuit of a Rapid, Photoactivatable, Nitroxyl Donor

Synthetic Explorations in the Pursuit of a Rapid, Photoactivatable, Nitroxyl Donor
  • Author : Mark Wesley Campbell
  • Publisher : Unknown
  • Release Date : 2017
  • ISBN : OCLC:1057288165
DOWNLOAD BOOKSynthetic Explorations in the Pursuit of a Rapid, Photoactivatable, Nitroxyl Donor

Nitroxyl (HNO) is a biologically relevant small molecule with considerable clinical promise for the treatment of heart failure. However, studies of the chemistry and biology of nitroxyl are hampered by its instability in aqueous solution. To aid in biological and chemical studies, nitroxyl donors (molecules that degrade to release HNO) have been synthesized which utilize a 3-hydroxy-2-naphthyl methyl (HNM) OH protecting group. Our group0́9s focus is on the synthesis of nitroxyl donors that rapidly release HNO under physiological

Reactive Species Detection in Biology

Reactive Species Detection in Biology
  • Author : Frederick A. Villamena
  • Publisher : Elsevier
  • Release Date : 2016-10-23
  • ISBN : 9780124200807
DOWNLOAD BOOKReactive Species Detection in Biology

Reactive Species Detection in Biology: From Fluorescence to Electron Paramagnetic Resonance Spectroscopy discusses the reactive oxygen species that have been implicated in the pathogenesis of various diseases, presenting theories, chemistries, methodologies, and various applications for the detection of reactive species in biological systems, both in-vitro and in-vivo. Techniques covered include fluorescence, high performance chromatography, mass spectrometry, immunochemistry, and electron paramagnetic resonance spectroscopy. Probe design and development are also reviewed in order to advance new approaches in radical detection through synthesis,

Oxidation and Antioxidants in Organic Chemistry and Biology

Oxidation and Antioxidants in Organic Chemistry and Biology
  • Author : Evgeny T. Denisov,Igor B. Afanas'ev
  • Publisher : CRC Press
  • Release Date : 2005-03-29
  • ISBN : 9781420030853
DOWNLOAD BOOKOxidation and Antioxidants in Organic Chemistry and Biology

Providing a comprehensive review of reactions of oxidation for different classes of organic compounds and polymers, and biological processes mediated by free radicals, Oxidation and Antioxidants in Organic Chemistry and Biology puts the data and bibliographical information you need into one easy-to-use resource. You will find up-to-date information about mechanisms of action of antioxidants, their reactivity, reactions of intermediates, synergism, and antioxidants with cyclic mechanism action. Supplying useful, quantitative data in tables that make the information easy to find, the

Nitrification

Nitrification
  • Author : Bess B. Ward,Daniel J. Arp,Martin G. Klotz
  • Publisher : American Society for Microbiology Press
  • Release Date : 2011-03-25
  • ISBN : 9781555814816
DOWNLOAD BOOKNitrification

A full review of the latest research findings on microbes involved in conventional aerobic nitrification, anaerobic ammonia oxidation, and related processes. • Examines the four principal groups of nitrifying microbes including conventional aerobic bacterial ammonia oxidizers, recently discovered aerobic archaeal ammonia oxidizers, anaerobic ammonia-oxidizing planctomycetes, and nitrite-oxidizing bacteria. • Provides current information on the ecology, phylogeny, biochemistry, molecular biology, and genomics of each group of microbes. • Discusses the latest industrial applications of nitrification and anammox processes, and explores the ecology of nitrification

Bioactive Spin Labels

Bioactive Spin Labels
  • Author : Renat I. Zhdanov
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-06-29
  • ISBN : 9783642487248
DOWNLOAD BOOKBioactive Spin Labels

Bioactive Spin Labels is a collection of contributions by leading experts on nitroxyl radicals and their application in biomedicine. These compounds are used as side specific contrast agents for in-vivo EPR techniques. Their potential as drugs is investigated. Bioactive Spin Labels is a must for researchers in bioorganic chemistry, pharmacology and biomedicine.

Nitric Oxide

Nitric Oxide
  • Author : Lester Packer,Enrique Cadenas
  • Publisher : Gulf Professional Publishing
  • Release Date : 2005-09
  • ISBN : 0121828018
DOWNLOAD BOOKNitric Oxide

Since the inception of the series, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all field of life sciences. This final volume in the five-part Nitric Oxide series supplements MIE volumes 268, 269, 301 and 359. Nitric Oxide impinges on a wide range of fields in biological research, particularly in the areas of biomedicine and cell and organic biology, as well

Synthetic Chemistry of Stable Nitroxides

Synthetic Chemistry of Stable Nitroxides
  • Author : L. B. Volodarsky,V.A. Reznikov,V.I. Ovcharenko
  • Publisher : CRC Press
  • Release Date : 2017-11-22
  • ISBN : 9781351357425
DOWNLOAD BOOKSynthetic Chemistry of Stable Nitroxides

This important book is devoted to covering the synthetic aspects of nitroxide chemistry. The problems of application and physicochemical properties of nitroxides are considered in the context of the choice of necessary radical structures, convenient precursors, and strategy of the synthesis. The book offers comparisons of the concrete classes of nitroxides to help reveal the structural peculiarities and synthetic abilities of compounds of different classes. It also summarizes data on the magneto-structural correlation for the metal complexes with 3-imidazoline nitroxides

Pulsed Electron–Electron Double Resonance

Pulsed Electron–Electron Double Resonance
  • Author : Yuri D. Tsvetkov,Michael K. Bowman,Yuri A. Grishin
  • Publisher : Springer
  • Release Date : 2018-12-28
  • ISBN : 9783030053727
DOWNLOAD BOOKPulsed Electron–Electron Double Resonance

This book covers the basic theory and techniques, as well as various applications of pulsed electron–electron double resonance (PELDOR or DEER). This electron paramagnetic resonance technique is able to measure the distances and the distribution of distances between electron spins in the 1.5–15 nanometer scale; to determine the geometry of spin-labeled molecules; to estimate the number of interacting spins in spin clusters; and to characterize the spatial distribution of paramagnetic centers. As a result, PELDOR is now a popular method

Progress in Inorganic Chemistry

Progress in Inorganic Chemistry
  • Author : Kenneth D. Karlin
  • Publisher : John Wiley & Sons
  • Release Date : 2005-06-14
  • ISBN : 9780471725558
DOWNLOAD BOOKProgress in Inorganic Chemistry

The cutting edge of scientific reporting . . . PROGRESS in Inorganic Chemistry Nowhere is creative scientific talent busier than in the world ofinorganic chemistry experimentation. Progress in InorganicChemistry continues in its tradition of being the most respectedavenue for exchanging innovative research. This series providesinorganic chemists and materials scientists with a forum forcritical, authoritative evaluations of advances in every area ofthe discipline. With contributions from internationally renownedchemists, this latest volume offers an in-depth, far-rangingexamination of the changing face of the field, providing atantalizing

Reactive Oxygen Species in Biological Systems: An Interdisciplinary Approach

Reactive Oxygen Species in Biological Systems: An Interdisciplinary Approach
  • Author : Carol Colton,Daniel Gilbert
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-05-08
  • ISBN : 9780306468063
DOWNLOAD BOOKReactive Oxygen Species in Biological Systems: An Interdisciplinary Approach

Reactive oxygen species (ROS) which include free radicals, peroxides, singlet oxygen, ozone, and nitrogen monoxide and dioxide free radicals, is an area of intense research. This volume covers (1) the destruction of cellular function by ROS resulting in pathological states; (2) the protection by ROS of an organism against invading organisms that cause infections; and (3) the role of ROS in normal physiological processes. Designed for beginning graduate students, this book gives a concise overview of the field.

An Examination of the Physiologically Relevant Chemistry of Nitroxyl (HNO)

An Examination of the Physiologically Relevant Chemistry of Nitroxyl (HNO)
  • Author : Natalie Mikki Cook
  • Publisher : Unknown
  • Release Date : 2003
  • ISBN : UCLA:L0087458626
DOWNLOAD BOOKAn Examination of the Physiologically Relevant Chemistry of Nitroxyl (HNO)

Porphyrins: Advances in Research and Application: 2011 Edition

Porphyrins: Advances in Research and Application: 2011 Edition
  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release Date : 2012-01-09
  • ISBN : 9781464929939
DOWNLOAD BOOKPorphyrins: Advances in Research and Application: 2011 Edition

Porphyrins: Advances in Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Porphyrins. The editors have built Porphyrins: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Porphyrins in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Porphyrins: Advances in Research and Application: 2011 Edition has been produced