The Cellular Secretome and Organ Crosstalk

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  • Publisher : Academic Press
  • Release : 12 June 2018
  • ISBN : 9780128097199
  • Page : 240 pages
  • Rating : 4.5/5 from 103 voters

The Cellular Secretome and Organ Crosstalk Book PDF summary

The Cellular Secretome and Organ Crosstalk focuses on the release of peptides and proteins from different organs and their specific functions in metabolic regulation and cell- and organ crosstalk. The book is written for experts in the field, however, for each topic, helpful references are included. The book also includes technical sections that summarize the state-of-the-art of secretome and crosstalk analysis. This book fulfills the need for a resource that comprehensively describes the current knowledge of secretome biology in health and disease. Communication between different organs involves lipids and other small molecules and a host of proteins and peptides comprising the secretome of different organs (organokinome). More than 600 adipokines have been identified, and an increasing number of hepatokines and myokines have recently been discovered with mostly unknown physiological impact. Importantly, an aberrant signature of the organokinome may be critically underlying a variety of metabolic diseases and may determine the individual susceptibility to disease development. Summarizes our current knowledge on the secretome of different cells and tissues Dissects auto-, para- and endocrine functions of major secreted peptides and proteins Analyzes the secretory malfunction of different cells and its impact for disease development Authored by a leader in the field, presenting a coherent view on this very complex topic

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The Cellular Secretome and Organ Crosstalk

The Cellular Secretome and Organ Crosstalk
  • Author : Juergen Eckel
  • Publisher : Academic Press
  • Release Date : 2018-06-12
  • ISBN : 9780128097199
DOWNLOAD BOOKThe Cellular Secretome and Organ Crosstalk

The Cellular Secretome and Organ Crosstalk focuses on the release of peptides and proteins from different organs and their specific functions in metabolic regulation and cell- and organ crosstalk. The book is written for experts in the field, however, for each topic, helpful references are included. The book also includes technical sections that summarize the state-of-the-art of secretome and crosstalk analysis. This book fulfills the need for a resource that comprehensively describes the current knowledge of secretome biology in health

Scientific Principles of Adipose Stem Cells

Scientific Principles of Adipose Stem Cells
  • Author : Lauren Kokai,Kacey Marra,J. Peter Rubin
  • Publisher : Academic Press
  • Release Date : 2021-09-01
  • ISBN : 9780128193778
DOWNLOAD BOOKScientific Principles of Adipose Stem Cells

Scientific Principles of Adipose Stem Cells provides readers with in-depth and expert knowledge on adipose stem cells, their developmental biologic origins, foundational research on ASC signaling mechanisms and immunomodulatory properties, and clinical insights into applications in regenerative medicine. Topics covered include basic adipose stem cell developmental biology and mechanisms of regulating self-renewal and activation in the stem cell niche, important methods for isolation and characterizing ASCs, and data on the impact on human demographics (age, sex, BMI) on ASC phenotype.

Current Challenges for Targeting Brown Fat Thermogenesis to Combat Obesity

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  • Publisher : Frontiers Media SA
  • Release Date : 2020-12-28
  • ISBN : 9782889662821
DOWNLOAD BOOKCurrent Challenges for Targeting Brown Fat Thermogenesis to Combat Obesity

The Biology and Therapeutic Application of Mesenchymal Cells - Set

The Biology and Therapeutic Application of Mesenchymal Cells - Set
  • Author : Kerry Atkinson
  • Publisher : John Wiley & Sons
  • Release Date : 2017-01-17
  • ISBN : 9781118907511
DOWNLOAD BOOKThe Biology and Therapeutic Application of Mesenchymal Cells - Set

The Biology and Therapeutic Application of Mesenchymal Cells comprehensively describes the cellular and molecular biology of mesenchymal stem cells and mesenchymal stromal cells, describing their therapeutic potential in a wide variety of preclinical models of human diseases and their mechanism of action in these preclinical models. Chapters also discuss the current status of the use of mesenchymal stem and stromal cells in clinical trials in a wide range of human diseases and disorders, for many of which there are limited,

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The Plasticity of Skeletal Muscle
  • Author : Kunihiro Sakuma
  • Publisher : Springer
  • Release Date : 2017-03-01
  • ISBN : 9789811032929
DOWNLOAD BOOKThe Plasticity of Skeletal Muscle

This book discusses recent advances and various topics in plasticity of skeletal muscle from the perspectives of morphology, biological function, and clinical applications. Skeletal muscle is a highly plastic organ to adapt to environmental various demands, appears to endocrine various myokines, which flow into blood to protect the recognizing function of brain and inhibit the appearance of several cancer tumorigenesis. The book deals with current stem-cell based, pharmacological, and nutritional therapies for muscle wasting (sarcopenia, cachexia, and muscular dystrophy). It

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  • Publisher : Springer Science & Business Media
  • Release Date : 2011-04-07
  • ISBN : 9783642168611
DOWNLOAD BOOKExtracellular Matrix Degradation

Regulated turnover of extracellular matrix (ECM) is an important component of tissue homeostasis. In recent years, the enzymes that participate in, and control ECM turnover have been the focus of research that touches on development, tissue remodeling, inflammation and disease. This volume in the Biology of Extracellular Matrix series provides a review of the known classes of proteases that degrade ECM both outside and inside the cell. The specific EMC proteases that are discussed include cathepsins, bacterial collagenases, matrix metalloproteinases,

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  • Publisher : Unknown
  • Release Date : 1997-01-01
  • ISBN : 1570594201
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Pericyte Biology in Different Organs

Pericyte Biology in Different Organs
  • Author : Alexander Birbrair
  • Publisher : Springer
  • Release Date : 2019-04-01
  • ISBN : 9783030110932
DOWNLOAD BOOKPericyte Biology in Different Organs

The present book is an attempt to describe the most recent developments in the area of pericyte biology which is one of the emergent hot topics in the field of molecular and cellular biology today. Here, we present a selected collection of thirteen detailed chapters on what we know so far about pericytes in distinct organs in physiological and pathological conditions. Further, it provides an update on the most novel functions attributed to these cells and will introduce a newer

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  • Publisher : Frontiers Media SA
  • Release Date : 2022-01-05
  • ISBN : 9782889719495
DOWNLOAD BOOKOrgan Fibrosis: Pathogenesis, Biomarkers and Therapeutic Targets

Lung Stem Cells in Development, Health and Disease

Lung Stem Cells in Development, Health and Disease
  • Author : Nikolic, Marko Z.,Hogan, Brigid L.M.
  • Publisher : European Respiratory Society
  • Release Date : 2021-04-01
  • ISBN : 9781849841344
DOWNLOAD BOOKLung Stem Cells in Development, Health and Disease

Most organs in the adult human body are able to maintain themselves and undergo repair after injury; these processes are largely dependent on stem cells. In this Monograph, the Guest Editors bring together leading authors in the field to provide information about the different classes of stem cells present both in the developing and adult lung: where they are found, how they function in homeostasis and pathologic conditions, the mechanisms that regulate their behaviour, and how they may be harnessed

Nutrition in the Prevention and Treatment of Abdominal Obesity

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  • Author : Ronald Ross Watson
  • Publisher : Elsevier
  • Release Date : 2014-02-26
  • ISBN : 9780124079342
DOWNLOAD BOOKNutrition in the Prevention and Treatment of Abdominal Obesity

Nutrition in the Prevention and Treatment of Abdominal Obesity focuses on the important roles that exercise, dietary changes, and foods play in promoting as well as reducing visceral fat. Nutritionists, dieticians, and healthcare providers seeking to address the abdominal obesity epidemic will use this comprehensive resource as a tool in their long-term goal of preventing chronic diseases, especially heart, vascular, and diabetic diseases. Experts from a broad range of disciplines are involved in dealing with the consequences of excessive abdominal

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  • Publisher : Springer Nature
  • Release Date : 2022-01-01
  • ISBN : 9783030770525
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In this volume, the contributing authors from top labs involved in stem cell theranostics share the latest advances in the field of stem cell research. The book covers many aspects of stem cell-based therapy and the progress made toward stem cell therapy for liver, ocular, and cardiovascular diseases as well as cancer. This volume serves as a continuation of Prof. Khawaja Husnain Haider’s previously edited books pertaining to stem cells-based therapnostics. This is an ideal book for researchers involved

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  • Author : Wanda Lattanzi,Maria Concetta Geloso
  • Publisher : Frontiers Media SA
  • Release Date : 2016-03-14
  • ISBN : 9782889197774
DOWNLOAD BOOKCrosstalk between the osteogenic and neurogenic stem cell niches: how far are they from each other?

Somatic stem cells reside in definite compartments, known as "niches", within developed organs and tissues, being able to renew themselves, differentiate and ensure tissue maintenance and repair. In contrast with the original dogmatic distinction between renewing and non-renewing tissues, somatic stem cells have been found in almost every human organism, including brain and heart. (HSCs) and mesenchymal stem cells (MSCs), that intensely interacts. HSCs represent the common precursors of all mature blood cells. (Bone, cartilage, blood vessels, adipose tissue, and.),

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  • Release Date : 2022-08-22
  • ISBN : 9783030999957
DOWNLOAD BOOKFrom Obesity to Diabetes

Obesity is a major risk factor for the development of type 2 diabetes and its associated complications, a major socio-economic burden for health care systems. The worldwide prevalence of obesity doubled since 1980 and as a consequence the number of patients with diabetes has been continuously rising with more than 450 Mio. people suffering from this disease at the present time. Substantial progress has been made in understanding the molecular pathways leading from excessive fat accumulation to metabolic perturbation and finally diabetes manifestation.

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  • Publisher : Academic Press
  • Release Date : 2013-07-26
  • ISBN : 9780123964779
DOWNLOAD BOOKNutrition and Enhanced Sports Performance

Nutrition and Enhanced Sports Performance: Muscle Building, Endurance, and Strength provides a comprehensive overview to understanding the integrated impact of nutrition on performance. The book is divided into five main themes: An introductory overview of the role of nutrition in human health Various types of physical exercises, including cardiovascular training, resistance training, aerobic and anaerobic exercise, bioenergetics, and energy balance. This section also covers the nutritional requirements associated with various fitness programs, as well as exercise and nutritional requirements in