Synthesis of Best Seller Drugs

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  • Publisher : Academic Press
  • Release : 07 January 2016
  • ISBN : 9780124115248
  • Page : 868 pages
  • Rating : 4.5/5 from 103 voters

Synthesis of Best Seller Drugs Book PDF summary

Synthesis of Best-Seller Drugs is a key reference guide for all those involved with the design, development, and use of the best-selling drugs. Designed for ease of use, this book provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field. Describes methods of synthesis, bioactivity and related drugs in key therapeutic areas Reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and more Presents a practical layout designed for use as a quick reference tool by those working in drug design, development and implementation

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Synthesis of Best-Seller Drugs

Synthesis of Best-Seller Drugs
  • Author : Ruben Vardanyan,Victor Hruby
  • Publisher : Academic Press
  • Release Date : 2016-01-07
  • ISBN : 9780124115248
DOWNLOAD BOOKSynthesis of Best-Seller Drugs

Synthesis of Best-Seller Drugs is a key reference guide for all those involved with the design, development, and use of the best-selling drugs. Designed for ease of use, this book provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work

Synthesis of Essential Drugs

Synthesis of Essential Drugs
  • Author : Ruben Vardanyan,Victor Hruby
  • Publisher : Elsevier
  • Release Date : 2006-03-10
  • ISBN : 008046212X
DOWNLOAD BOOKSynthesis of Essential Drugs

Synthesis of Essential Drugs describes methods of synthesis, activity and implementation of diversity of all drug types and classes. With over 2300 references, mainly patent, for the methods of synthesis for over 700 drugs, along with the most widespread synonyms for these drugs, this book fills the gap that exists in the literature of drug synthesis. It provides the kind of information that will be of interest to those who work, or plan to begin work, in the areas of biologically active

The Art of Drug Synthesis

The Art of Drug Synthesis
  • Author : Douglas S. Johnson,Jie Jack Li
  • Publisher : John Wiley & Sons
  • Release Date : 2013-02-26
  • ISBN : 9781118678466
DOWNLOAD BOOKThe Art of Drug Synthesis

The Art of Drug Synthesis illustrates how chemistry, biology, pharmacokinetics, and a host of other disciplines come together to produce successful medicines. The authors have compiled a collection of 21 representative categories of drugs, from which they have selected as examples many of the best-selling drugs on the market today. An introduction to each drug is provided, as well as background to the biology, pharmacology, pharmacokinetics, and drug metabolism, followed by a detailed account of the drug synthesis. Edited by prominent

The Organic Chemistry of Drug Synthesis

The Organic Chemistry of Drug Synthesis
  • Author : Daniel Lednicer
  • Publisher : John Wiley & Sons
  • Release Date : 2007-12-14
  • ISBN : 9780470180662
DOWNLOAD BOOKThe Organic Chemistry of Drug Synthesis

The classic reference on the synthesis of medicinal agents -- now completely updated The seventh volume in the definitive series that provides a quick yet thorough overview of the synthetic routes used to access specific classesof therapeutic agents, this volume covers approximately 220 new non-proprietary drug entities introduced since the publication of Volume 6. Many of these compounds represent novel structural types firstidentified by sophisticated new cell-based assays. Specifically, a significant number of new antineoplastic and antiviral agents are covered. As in

Strategies for Organic Drug Synthesis and Design

Strategies for Organic Drug Synthesis and Design
  • Author : Daniel Lednicer
  • Publisher : John Wiley & Sons
  • Release Date : 2009-03-04
  • ISBN : 0470399597
DOWNLOAD BOOKStrategies for Organic Drug Synthesis and Design

This book examines and evaluates the strategies utilized to design and synthesize pharmaceutically active agents. Significant updates over the last 10 years since the publication of the 1st edition include synthesis of enantiomerically pure isomers, novel chemical methodologies, and new pharmaceutical agents targeted at novel biological endpoints. Written by an experienced successful author, this book meets the needs of a growing community of researchers in pharmaceutical R &D, as well as medical professionals, by providing a useful guide for designing and

Contemporary Drug Synthesis

Contemporary Drug Synthesis
  • Author : Jie Jack Li,Douglas S. Johnson,Drago R. Sliskovic,Bruce D. Roth
  • Publisher : Wiley-Interscience
  • Release Date : 2004-06-25
  • ISBN : UOM:39015059188220
DOWNLOAD BOOKContemporary Drug Synthesis

An integrated and insightful look at successful drug synthesis in today's drug discovery market The pharmaceutical industry is unquestionably vibrant today, with drug synthesis making a vital contribution. Whether in the early developmental stages of identifying and optimizing a lead, or the latter stages of process development and cost-effective scale-up, the ability to design elegant and economical synthetic routes is often a major factor in the eventual viability and commercial success of a drug. Contemporary Drug Synthesis examines how leading

An Introduction to Drug Synthesis

An Introduction to Drug Synthesis
  • Author : Graham L. Patrick
  • Publisher : Unknown
  • Release Date : 2015
  • ISBN : 0191073474
DOWNLOAD BOOKAn Introduction to Drug Synthesis

An Introduction to Drug Synthesis explores the central role played by organic synthesis in the process of drug design and development - from the generation of novel drug structures to the improved efficiency of large scale synthesis.

Piperidine-Based Drug Discovery

Piperidine-Based Drug Discovery
  • Author : Ruben Vardanyan
  • Publisher : Elsevier
  • Release Date : 2017-06-12
  • ISBN : 9780128134283
DOWNLOAD BOOKPiperidine-Based Drug Discovery

Piperidine-Based Drug Discovery outlines the complexities of Piperidine scaffold use in drug discovery, including derivative chemistry, structural properties, methods of synthesis and practical implementations. Piperidine scaffolds are the cornerstones of over 70 commercialized drugs (including multiple blockbusters). Designed as a guide for both experts and students working in this and related areas, it is hoped that this volume will encourage and inspire the continued design and development of novel pharmaceuticals based on Piperidine and its derivatives. Heterocyclic compounds are of central

Advances in Heterocyclic Chemistry

Advances in Heterocyclic Chemistry
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2018-05-21
  • ISBN : 9780128155387
DOWNLOAD BOOKAdvances in Heterocyclic Chemistry

Advances in Heterocyclic Chemistry, Volume 126, is the definitive series in the field, one that is of great importance to organic chemists, polymer chemists and many biological scientists. Because biology and organic chemistry increasingly intersect, the associated nomenclature is used more frequently in explanations. Updates to this release include sections on The Literature of Heterocyclic Chemistry, Part XVI, 2016, The preparation and properties of heteroarylazulenes and hetero-fused azulenes, Recent developments in pyrazole chemistry, Yne, Ene-Yne Synthetic Approaches to Heterocycles, Appel Salt and

Modern Drug Synthesis

Modern Drug Synthesis
  • Author : Jie Jack Li,Douglas S. Johnson
  • Publisher : John Wiley & Sons
  • Release Date : 2013-03-27
  • ISBN : 9781118701249
DOWNLOAD BOOKModern Drug Synthesis

Following Contemporary Drug Synthesis and The Art of Drug Synthesis (Wiley, 2004 and 2007), two well-received works, is this new book that demystifies the process of modern drug discovery for practitioners and students. An enhanced introduction covers areas such as background, pharmacology, SAR, PK/PD, efficacy, and safety. Focusing on the advantages of process synthesis versus the discovery synthetic route, Modern Drug Synthesis features authoritative coverage by distinguished editors and authors (some chapter authors are the actual inventor of the drug) of

Top Drugs

Top Drugs
  • Author : John Saunders
  • Publisher : Unknown
  • Release Date : 2011
  • ISBN : 0191848603
DOWNLOAD BOOKTop Drugs

Many of today's best selling drugs are first made in the chemical laboratory on a very small scale many years before they enter the market place. During the intervening period, organic chemists investigate alternative methods both to improve the overall yield of the process and to ensure that it operates safely on a manufacturing scale. This book describes how each drug works and then reviews the most efficient routes to their synthesis.

Pharmaceutical Process Chemistry for Synthesis

Pharmaceutical Process Chemistry for Synthesis
  • Author : Peter J. Harrington
  • Publisher : John Wiley & Sons
  • Release Date : 2011-02-23
  • ISBN : 0470922869
DOWNLOAD BOOKPharmaceutical Process Chemistry for Synthesis

There is a need to explain that generic versions of a drug may not be manufactured by the same process as brand-name drugs and that the different processes may have dramatically different environmental impacts. Two global forces are at odds today—the push for "greener" processes and the push for lower drug prices. This book brings this conflict into sharp focus by discussing in detail the published process chemistry for top-selling small molecule drugs. Providing insights about process route selection,

An Introduction to Drug Synthesis

An Introduction to Drug Synthesis
  • Author : Graham L. Patrick
  • Publisher : Oxford University Press, USA
  • Release Date : 2015-01
  • ISBN : 9780198708438
DOWNLOAD BOOKAn Introduction to Drug Synthesis

'Introduction to Drug Synthesis' explores the central role played by organic synthesis in the process of drug design and development - from the generation of novel drug structures to the improved efficiency of large scale synthesis.

Contemporary Drug Synthesis

Contemporary Drug Synthesis
  • Author : Jie Jack Li,Douglas S. Johnson,Drago R. Sliskovic,Bruce D. Roth
  • Publisher : John Wiley & Sons
  • Release Date : 2004-12-27
  • ISBN : 9780471686736
DOWNLOAD BOOKContemporary Drug Synthesis

An integrated and insightful look at successful drug synthesis in today's drug discovery market The pharmaceutical industry is unquestionably vibrant today, with drug synthesis making a vital contribution. Whether in the early developmental stages of identifying and optimizing a lead, or the latter stages of process development and cost-effective scale-up, the ability to design elegant and economical synthetic routes is often a major factor in the eventual viability and commercial success of a drug. Contemporary Drug Synthesis examines how leading

Innovative Drug Synthesis

Innovative Drug Synthesis
  • Author : Jie Jack Li,Douglas S. Johnson
  • Publisher : John Wiley & Sons
  • Release Date : 2015-11-19
  • ISBN : 9781118820025
DOWNLOAD BOOKInnovative Drug Synthesis

This book covers all aspects of the medicinal chemistry of the latest drugs, and the cutting-edge science associated with them. Following the editors’ 3 successful drug synthesis books, this provides expert analysis of the pros and cons of different synthetic routes and demystifies the process of modern drug discovery for practitioners and researchers. Summarizes for each drug: respective disease area, important properties and SAR (structure-activity relationship), and chemical synthesis routes / options Includes case studies in each chapter Illustrates how chemistry, biology,