Polymers and Nanomaterials for Gene Therapy

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  • Publisher : Woodhead Publishing
  • Release : 09 January 2016
  • ISBN : 9780081005217
  • Page : 302 pages
  • Rating : 4.5/5 from 103 voters

Polymers and Nanomaterials for Gene Therapy Book PDF summary

Polymers and Nanomaterials for Gene Therapy provides the latest information on gene therapy, a topic that has attracted significant attention over the past two decades for the treatment of inherited and acquired genetic diseases. Major research efforts are currently focused on designing suitable carrier vectors that compact and protect oligonucleotides for gene therapy. The book explores the most recent developments in the field of polymer science and nanotechnology, and how these advancements have helped in the design of advanced materials. Non-viral vector systems, including cationic lipids, polymers, dendrimers, peptides and nanoparticles, are potential routes for compacting DNA for systemic delivery. However, unlike viral analogues that have no difficulty in overcoming cellular barriers and immune defense mechanisms, non-viral gene carriers consistently exhibit significant reduced transfection efficiency due to numerous extra- and intracellular obstacles. Therefore, biocompatibility and potential for large-scale production make these compounds increasingly attractive for gene therapy. This book contains chapters on the engineering of polymers and nanomaterials for gene therapy, and how they can form complexes with DNA and avoid both in vitro and in vivo barriers. Other chapters describe in vitro, ex vivo, in vivo gene therapy studies, and the current issues affecting non-viral gene therapy. Explores current challenges in the research of genetic diseases Discusses polymers for gene therapy and their function in designing advanced materials Provides examples of organic and inorganic nanomaterials for gene therapy Includes labeling, targeting, and assays Looks at characterization, physico-(bio)chemical properties, and applications

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Polymers and Nanomaterials for Gene Therapy

Polymers and Nanomaterials for Gene Therapy
  • Author : Ravin Narain
  • Publisher : Woodhead Publishing
  • Release Date : 2016-01-09
  • ISBN : 9780081005217
DOWNLOAD BOOKPolymers and Nanomaterials for Gene Therapy

Polymers and Nanomaterials for Gene Therapy provides the latest information on gene therapy, a topic that has attracted significant attention over the past two decades for the treatment of inherited and acquired genetic diseases. Major research efforts are currently focused on designing suitable carrier vectors that compact and protect oligonucleotides for gene therapy. The book explores the most recent developments in the field of polymer science and nanotechnology, and how these advancements have helped in the design of advanced materials.

Polymer Science and Nanotechnology

Polymer Science and Nanotechnology
  • Author : Ravin Narain
  • Publisher : Elsevier
  • Release Date : 2020-06-16
  • ISBN : 9780128168073
DOWNLOAD BOOKPolymer Science and Nanotechnology

Polymer Science and Nanotechnology: Fundamentals and Applications brings together the latest advances in polymer science and nanoscience. Sections explain the fundamentals of polymer science, including key aspects and methods in terms of molecular structure, synthesis, characterization, microstructure, phase structure and processing and properties before discussing the materials of particular interest and utility for novel applications, such as hydrogels, natural polymers, smart polymers and polymeric biomaterials. The second part of the book examines essential techniques in nanotechnology, with an emphasis on

Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics

Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics
  • Author : Prashant Kesharwani,Kishore M. Paknikar,Virendra Gajbhiye
  • Publisher : Academic Press
  • Release Date : 2019-07-08
  • ISBN : 9780128173312
DOWNLOAD BOOKPolymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics

Polymeric Nanoparticles as Promising Tool for Anti-cancer Therapeutics provides an understanding of polymeric compounds and their use in cancer therapies. The book begins by giving an overview of the current status, future challenges and potential utilization of polymeric nanoparticles. It then covers specific polymeric nanoparticles through contributions from world-renowned experts and researchers. Chapters examine specific polymeric nanoparticles, their development as potential targeted delivery systems, and cancer characteristics that can be targeted for therapy development. The book synthesizes current research trends

Drug Targeting and Stimuli Sensitive Drug Delivery Systems

Drug Targeting and Stimuli Sensitive Drug Delivery Systems
  • Author : Alexandru Mihai Grumezescu
  • Publisher : William Andrew
  • Release Date : 2018-05-21
  • ISBN : 9780128136904
DOWNLOAD BOOKDrug Targeting and Stimuli Sensitive Drug Delivery Systems

Drug Targeting and Stimuli Sensitive Drug Delivery Systems covers recent advances in the area of stimuli sensitive drug delivery systems, providing an up-to-date overview of the physical, chemical, biological and multistimuli-responsive nanosystems. In addition, the book presents an analysis of clinical status for different types of nanoplatforms. Written by an internationally diverse group of researchers, it is an important reference resource for both biomaterials scientists and those working in the pharmaceutical industry who are looking to help create more effective

Polymeric Nanomaterials in Nanotherapeutics

Polymeric Nanomaterials in Nanotherapeutics
  • Author : Anonim
  • Publisher : Elsevier
  • Release Date : 2018-10-26
  • ISBN : 9780128139332
DOWNLOAD BOOKPolymeric Nanomaterials in Nanotherapeutics

Polymeric Nanomaterials in Nanotherapeutics describes how polymeric nanosensors and nanorobotics are used for biomedical instrumentation, surgery, diagnosis and targeted drug delivery for cancer, pharmacokinetics, monitoring of diabetes and healthcare. Key areas of coverage include drug administration and formulations for targeted delivery and release of active agents (drug molecules) to non-healthy tissues and cells. The book demonstrates how these are applied to dental work, wound healing, cancer, cardiovascular diseases, neurodegenerative disorders, infectious diseases, chronic inflammatory diseases, metabolic diseases, and more. Methods

Multifunctional Polymeric Materials for Drug and Gene Delivery

Multifunctional Polymeric Materials for Drug and Gene Delivery
  • Author : Yakai Feng,Abraham Jacob Domb,Bin He,Wenzhong Li
  • Publisher : Frontiers Media SA
  • Release Date : 2022-05-30
  • ISBN : 9782889762743
DOWNLOAD BOOKMultifunctional Polymeric Materials for Drug and Gene Delivery

Advanced Technology for Delivering Therapeutics

Advanced Technology for Delivering Therapeutics
  • Author : Sabyasachi Maiti,Kalyan Kumar Sen
  • Publisher : BoD – Books on Demand
  • Release Date : 2017-05-11
  • ISBN : 9789535131212
DOWNLOAD BOOKAdvanced Technology for Delivering Therapeutics

The goal of any novel drug delivery system is to provide therapeutic benefits to the patients by increasing duration of drug action, reducing dosing frequency, and controlling drug release rate at the target site, thereby reducing unwanted side effects. Advanced Technology for Delivering Therapeutics is a reference book that covers recent developments in the field of drug delivery science and technology. The purpose of this book is to bring together descriptions of some selective technologies including new and promising nanotechnology

Advances in Polymeric Nanomaterials for Biomedical Applications

Advances in Polymeric Nanomaterials for Biomedical Applications
  • Author : Anil Kumar Bajpai,Rajesh Kumar Saini
  • Publisher : Elsevier
  • Release Date : 2021-04-02
  • ISBN : 9780128146576
DOWNLOAD BOOKAdvances in Polymeric Nanomaterials for Biomedical Applications

Advances in Polymeric Nanomaterials for Biomedical Applications examines advanced polymer synthetic strategies for developing novel biomaterials for use in medicine. With a strong focus on fundamentals and structure, the authors also explore their fabrication, along with their current and potential biomedical applications. The book begins with a look at the fundamentals of polymeric nanomaterials and their properties and then discusses the design of biomaterials and their applications in drug delivery. Further chapters explore important applications, such as imaging and regenerative

Biopolymeric Nanomaterials

Biopolymeric Nanomaterials
  • Author : Shamsher S. Kanwar,Ashok Kumar,Tuan Anh Nguyen,Swati Sharma,Yassine Slimani
  • Publisher : Elsevier
  • Release Date : 2021-09-24
  • ISBN : 9780323853286
DOWNLOAD BOOKBiopolymeric Nanomaterials

Biopolymeric Nanomaterials: Fundamentals and Applications outlines the fundamental design concepts and emerging applications of biopolymeric nanomaterials. The book also provides information on emerging applications of biopolymeric nanomaterials, including in biomedicine, manufacturing and water purification, as well as assessing their physical, chemical and biological properties. This is an important reference source for materials scientists, engineers and biomedical scientists who are seeking to increase their understanding of how polymeric nanomaterials are being used for a range of biomedical and industrial applications. Biopolymeric

Synthetic DNA Delivery Systems

Synthetic DNA Delivery Systems
  • Author : Dan Luo,W. Mark Saltzman
  • Publisher : Springer Science & Business Media
  • Release Date : 2003-09-30
  • ISBN : 0306477017
DOWNLOAD BOOKSynthetic DNA Delivery Systems

DNA delivery into cells is a rapidly developing area in gene therapy and biotechnology. Moreover, it is a powerful research tool to determine gene structure, regulation, and function. Viral methods of DNA delivery are well-characterized and efficient, but little is known about the toxicity and immunogenecity of viral vectors. As a result, non-viral, transfection methods of DNA delivery are of increasing interest. Synthetic DNA Delivery Systems is a comprehensive and current resource on DNA transfection. The use of histidine-rich peptides

Nonviral Vectors for Gene Therapy

Nonviral Vectors for Gene Therapy
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2014-11-18
  • ISBN : 9780128003671
DOWNLOAD BOOKNonviral Vectors for Gene Therapy

The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in our knowledge of genetics. Advances in Genetics continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. Includes methods for testing with ethical, legal, and social implications Critically analyzes future directions Written and edited by recognized leaders in the field

Carbon Nanomaterials for Bioimaging, Bioanalysis, and Therapy

Carbon Nanomaterials for Bioimaging, Bioanalysis, and Therapy
  • Author : Yuen Y. Hui,Huang-Cheng Chang,Haifeng Dong,Xueji Zhang
  • Publisher : John Wiley & Sons
  • Release Date : 2019-01-29
  • ISBN : 9781119373452
DOWNLOAD BOOKCarbon Nanomaterials for Bioimaging, Bioanalysis, and Therapy

A comprehensive reference on biochemistry, bioimaging, bioanalysis, and therapeutic applications of carbon nanomaterials Carbon nanomaterials have been widely applied for biomedical applications in the past few decades, because of their unique physical properties, versatile functionalization chemistry, and biological compatibility. This book provides background knowledge at the entry level into the biomedical applications of carbon nanomaterials, focusing on three applications: bioimaging, bioanalysis, and therapy. Carbon Nanomaterials for Bioimaging, Bioanalysis and Therapy begins with a general introduction to carbon nanomaterials for biomedical

Gene Therapy

Gene Therapy
  • Author : Surendra Nimesh
  • Publisher : Woodhead Pub Limited
  • Release Date : 2013
  • ISBN : 1907568409
DOWNLOAD BOOKGene Therapy

Gene therapy is emerging as a new class of therapeutics for the treatment of inherited and acquired diseases. However, poor cellular uptake and instability of DNA in the physiological milieu limits its therapeutic potential, hence a vector which can protect and efficiently transport DNA to the target cells must be developed. Nanotechnology-based non-viral vectors have been proposed as potential candidates. Various polymeric nanoparticles have been shown to be suitable, with high cellular uptake efficiencies and reduced cytotoxicity. These delivery vectors

NanoBioMedicine

NanoBioMedicine
  • Author : Shailendra K. Saxena,S. M. Paul Khurana
  • Publisher : Springer Nature
  • Release Date : 2020-02-03
  • ISBN : 9789813298989
DOWNLOAD BOOKNanoBioMedicine

This book provides a comprehensive overview of the recent trends in various Nanotechnology-based therapeutics and challenges associated with its development. Nanobiotechnology is an interdisciplinary research that has wide applications in the various fields of biomedical research. The book discusses the various facets of the application of Nanotechnology in drug delivery, clinical diagnostics, Nanomedicine and treatment of infectious and chronic diseases. The book also highlights the recent advancements on important devices and applications that are based on Nanotechnology in medicine and

Advances in Nanomaterials for Drug Delivery

Advances in Nanomaterials for Drug Delivery
  • Author : Mahdi Karimi,Maryam Rad Mansouri,Navid Rabiee,Michael R Hamblin
  • Publisher : Morgan & Claypool Publishers
  • Release Date : 2018-12-05
  • ISBN : 9781681742892
DOWNLOAD BOOKAdvances in Nanomaterials for Drug Delivery

Nanomedicine is a developing field, which includes different disciplines such as material science, chemistry, engineering and medicine devoted to the design, synthesis and construction of high-tech nanostructures. The ability of these structures to have their chemical and physical properties tuned by structural modification, has allowed their use in drug delivery systems, gene therapy delivery, and various types of theranostic approaches. Colloidal noble metal nanoparticles and other nanostructures have many therapeutic and diagnostic applications. The concept of drug targeting as a