Overflow Metabolism

Book Overflow Metabolism Cover

Download book entitled Overflow Metabolism by Alexei Vazquez and published by Academic Press in PDF, EPUB and Kindle. Read Overflow Metabolism book directly from your devices anywhere anytime. Click Download Book button to get book file. Read some info about this book below.

  • Publisher : Academic Press
  • Release : 27 October 2017
  • ISBN : 9780128123355
  • Page : 84 pages
  • Rating : 4.5/5 from 103 voters

Overflow Metabolism Book PDF summary

Overflow Metabolism: From Yeast to Marathon Runners provides an overview of overflow metabolism, reviewing the major phenomenological aspects as observed in different organisms, followed by a critical analysis of proposed theories to explain overflow metabolism. In our ideal view of metabolism, we think of catabolism and anabolism. In catabolism nutrients break down to carbon dioxide and water to generate biochemical energy. In anabolism nutrients break down to generate building blocks for cell biosynthesis. Yet, when cells are pushed to high metabolic rates they exhibit incomplete catabolism of nutrients, with a lower energy yield and excretion of metabolic byproducts. This phenomenon, characterized by the excretion of metabolic byproducts that could otherwise be used for catabolism or anabolism, is generally known as overflow metabolism. Overflow metabolism is a ubiquitous phenotype that has been conserved during evolution. Examples are the acetate switch in the bacterium E. coli, Crabtree effect in unicellular eukaryote yeasts, the lactate switch in sports medicine, and the Warburg effect in cancer. Several theories have been proposed to explain this seemingly wasteful phenotype. Yet, there is no consensus about what determines overflow metabolism and whether it offers any selective advantage. Includes examples of overflow metabolism and major phenomenological features Features a critical view of proposed theories to explain overflow metabolism Provides a summary of our preview work, proposing molecular crowding as the cause of overflow metabolism, together with new unpublished results

DOWNLOAD BOOK

Overflow Metabolism

Overflow Metabolism
  • Author : Alexei Vazquez
  • Publisher : Academic Press
  • Release Date : 2017-10-27
  • ISBN : 9780128123355
DOWNLOAD BOOKOverflow Metabolism

Overflow Metabolism: From Yeast to Marathon Runners provides an overview of overflow metabolism, reviewing the major phenomenological aspects as observed in different organisms, followed by a critical analysis of proposed theories to explain overflow metabolism. In our ideal view of metabolism, we think of catabolism and anabolism. In catabolism nutrients break down to carbon dioxide and water to generate biochemical energy. In anabolism nutrients break down to generate building blocks for cell biosynthesis. Yet, when cells are pushed to high

The significance of overflow metabolism in the physiology and g...

The significance of overflow metabolism in the physiology and g...
  • Author : Oense Martinus Neijssel
  • Publisher : Unknown
  • Release Date : 1976
  • ISBN : UCAL:B2705177
DOWNLOAD BOOKThe significance of overflow metabolism in the physiology and g...

Insect-Plant Interactions

Insect-Plant Interactions
  • Author : Elizabeth A. Bernays
  • Publisher : CRC Press
  • Release Date : 2019-10-01
  • ISBN : 9781000697551
DOWNLOAD BOOKInsect-Plant Interactions

First Published in 1989, this book explores the relationship between plants and insects and the ways in which they interact with each other. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for students of oncology, and other practitioners in their respective fields.

The Effect of Cations on Microbial Metabolism and Growth Energetics

The Effect of Cations on Microbial Metabolism and Growth Energetics
  • Author : Ed T. Buurman
  • Publisher : Unknown
  • Release Date : 1991
  • ISBN : UCAL:B3827444
DOWNLOAD BOOKThe Effect of Cations on Microbial Metabolism and Growth Energetics

Physiological Stress Responses in Bioprocesses

Physiological Stress Responses in Bioprocesses
  • Author : Sven-Olof Enfors,Thomas Egli
  • Publisher : Springer Science & Business Media
  • Release Date : 2004-05-06
  • ISBN : 3540203117
DOWNLOAD BOOKPhysiological Stress Responses in Bioprocesses

This review series covers trends in modern biotechnology. All aspects of this interdisciplinary technology, where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science, are treated. Electronic version available at http://link.springer.de/series/abe/

Metabolic Regulation and Metabolic Engineering for Biofuel and Biochemical Production

Metabolic Regulation and Metabolic Engineering for Biofuel and Biochemical Production
  • Author : Kazuyuki Shimizu
  • Publisher : CRC Press
  • Release Date : 2017-07-12
  • ISBN : 9781351650106
DOWNLOAD BOOKMetabolic Regulation and Metabolic Engineering for Biofuel and Biochemical Production

The global warming problem is becoming critical year by year, causing climate disaster all over the world, where it has been believed that the CO2 gas emitted from the factories and the burning of fossil fuels may be one of the reasons of global warming. Moreover, the global stock of fossil fuels is limited, and may run out soon within several tens of years. Although wind, geo-thermal, and tide energies have been considered as clean energy sources, those depend on

Amino Acid Biosynthesis – Pathways, Regulation and Metabolic Engineering

Amino Acid Biosynthesis – Pathways, Regulation and Metabolic Engineering
  • Author : Volker F. Wendisch
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-03-24
  • ISBN : 9783540485964
DOWNLOAD BOOKAmino Acid Biosynthesis – Pathways, Regulation and Metabolic Engineering

This book presents the current knowledge of fundamental as well as applied microbiology of amino acids. Coverage details the amino acid biosynthetic pathways, their genetic and biochemical regulation, transport of amino acids and genomics of producing microorganisms. The book also examines the metabolic engineering of microorganisms for the biotechnological production of amino acids for use as pharmaceuticals and as food and feed additives.

Microbial Life History

Microbial Life History
  • Author : Steven A. Frank
  • Publisher : Princeton University Press
  • Release Date : 2022-08-16
  • ISBN : 9780691231198
DOWNLOAD BOOKMicrobial Life History

A powerful framework for understanding how natural selection shapes adaptation and biological design Design and diversity are the two great challenges in the study of life. Microbial Life History draws on the latest advances in microbiology to describe the fundamental forces of biological design and apply these evolutionary processes to a broad diversity of traits in microbial metabolism and biochemistry. Emphasizing how to formulate and test hypotheses of adaptation, Steven Frank provides a new foundation for exploring the evolutionary forces

Metabolism and Bacterial Pathogenesis

Metabolism and Bacterial Pathogenesis
  • Author : Tyrrell Conway,Paul S. Cohen
  • Publisher : John Wiley & Sons
  • Release Date : 2020-07-24
  • ISBN : 9781555818883
DOWNLOAD BOOKMetabolism and Bacterial Pathogenesis

Groundbreaking thinking on how bacterial metabolism is foundational to pathogenesis For too long, bacterial metabolism and bacterial pathogenesis have been studied as separate entities. However, the scientific community is beginning to realize that not only are bacterial nutrient acquisition and utilization essential for pathogenesis, but that interfering with the pathogen-specific metabolic pathways used during infection can regulate virulence factor expression and might lead to effective breakthroughs in a variety of treatments. Editors Paul Cohen and Tyrrell Conway, who pioneered the

Basic Biotechnology

Basic Biotechnology
  • Author : Colin Ratledge,Bjorn Kristiansen
  • Publisher : Cambridge University Press
  • Release Date : 2006-05-25
  • ISBN : 9780521840316
DOWNLOAD BOOKBasic Biotechnology

Biotechnology is one of the major technologies of the twenty-first century. Its wide-ranging, multi-disciplinary activities include recombinant DNA techniques, cloning and the application of microbiology to the production of goods from bread to antibiotics. In this new edition of the textbook Basic Biotechnology, biology and bioprocessing topics are uniquely combined to provide a complete overview of biotechnology. The fundamental principles that underpin all biotechnology are explained and a full range of examples are discussed to show how these principles are

A Metabolic Engineering Approach to Study Overflow Metabolism in Escherichia Coli

A Metabolic Engineering Approach to Study Overflow Metabolism in Escherichia Coli
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2005
  • ISBN : OCLC:926125463
DOWNLOAD BOOKA Metabolic Engineering Approach to Study Overflow Metabolism in Escherichia Coli

Secondary Metabolism in Plant Cell Cultures

Secondary Metabolism in Plant Cell Cultures
  • Author : International Association of Plant Cell and Tissue Culture
  • Publisher : CUP Archive
  • Release Date : 1986-09-25
  • ISBN : 0521328896
DOWNLOAD BOOKSecondary Metabolism in Plant Cell Cultures

This 1986 book, derived from the meeting held by the International Association of Plant Cell and Tissue Culture in Sheffield in July 1985, describes the state of research in the area of secondary metabolism in plant cell and tissue culture. Such cultures are a major tool in horticulture and agriculture, and in the chemical industry.

Fluxomics and Metabolic Analysis in Systems Microbiology

Fluxomics and Metabolic Analysis in Systems Microbiology
  • Author : Wei Xiong,Yinjie Tang,Lars Keld Nielsen
  • Publisher : Frontiers Media SA
  • Release Date : 2019-10-21
  • ISBN : 9782889630691
DOWNLOAD BOOKFluxomics and Metabolic Analysis in Systems Microbiology

The Metabolic Pathway Engineering Handbook

The Metabolic Pathway Engineering Handbook
  • Author : Christina Smolke
  • Publisher : CRC Press
  • Release Date : 2009-07-28
  • ISBN : 1439802971
DOWNLOAD BOOKThe Metabolic Pathway Engineering Handbook

This first volume of the Metabolic Pathway Engineering Handbook provides an overview of metabolic pathway engineering with a look towards the future. It discusses cellular metabolism, including transport processes inside the cell and energy generating reactions, as well as rare metabolic conversions. This volume also explores balances and reaction

The Metabolic Pathway Engineering Handbook, Two Volume Set

The Metabolic Pathway Engineering Handbook, Two Volume Set
  • Author : Christina Smolke
  • Publisher : CRC Press
  • Release Date : 2009-08-18
  • ISBN : 9781420005622
DOWNLOAD BOOKThe Metabolic Pathway Engineering Handbook, Two Volume Set

Christina Smolke, who recently developed a novel way to churn out large quantities of drugs from genetically modified brewer's yeast, is regarded as one of the most brilliant minds in biomedical engineering. In this handbook, she brings together pioneering scientists from dozens of disciplines to provide a complete record of accomplishment in metab