Overcoming Ovarian Cancer Chemoresistance

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  • Publisher : Academic Press
  • Release : 06 November 2020
  • ISBN : 9780128198414
  • Page : 188 pages
  • Rating : 4.5/5 from 103 voters

Overcoming Ovarian Cancer Chemoresistance Book PDF summary

Overcoming Ovarian Cancer Chemoresistance presents non-overlapping review chapters that discuss the state of the field in overcoming chemoresistance of ovarian cancer and treatment options before and following recurrence, considering the genetic makeup of the ovarian cancer patient and her tumor. With the uptake of both germline and somatic gene testing, clinicians can obtain a more comprehensive understanding of ovarian tumors and this book provides information to link the genetic makeup of a tumor (or patient) with the best available treatment. The book discusses topics such as strategies to fight chemo-resistance in ovarian cancer, circulating DNA as a monitor of response, BRCA mutations, ovarian cancer stem cells, immunotherapy and vaccines. Additionally, it brings a list of promising agents at clinical and pre-clinical stage that will impact the treatment in the near future. This book is a valuable source for cancer researchers, oncologists and several members of biomedical field who need to understand how to battle chemoresistance in ovarian cancer. Provides a comprehensive view of both biological and genetic determinants of resistance, as well as technical approaches to monitor response Discusses genetic reversions as a unique alteration and a new field of study Includes a chapter on upcoming and promising agents that are in the pre-clinical and early clinical space, to set the stage for future directions in the field

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Overcoming Ovarian Cancer Chemoresistance

Overcoming Ovarian Cancer Chemoresistance
  • Author : Goli Samimi,Christina Annunziata
  • Publisher : Academic Press
  • Release Date : 2020-11-06
  • ISBN : 9780128198414
DOWNLOAD BOOKOvercoming Ovarian Cancer Chemoresistance

Overcoming Ovarian Cancer Chemoresistance presents non-overlapping review chapters that discuss the state of the field in overcoming chemoresistance of ovarian cancer and treatment options before and following recurrence, considering the genetic makeup of the ovarian cancer patient and her tumor. With the uptake of both germline and somatic gene testing, clinicians can obtain a more comprehensive understanding of ovarian tumors and this book provides information to link the genetic makeup of a tumor (or patient) with the best available treatment.

Overcoming Drug Resistance in Gynecologic Cancers

Overcoming Drug Resistance in Gynecologic Cancers
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2021-08-11
  • ISBN : 9780128243008
DOWNLOAD BOOKOvercoming Drug Resistance in Gynecologic Cancers

Overcoming Drug Resistance in Gynecologic Cancers provides up-to-date information related to important gynecologic cancers and focuses on mechanisms of drug resistance, genetics, signaling, immunology, health disparities, nanotechnology, economic considerations and financial impacts. The book covers not only drug resistance but also important means to reverse resistance both in the laboratory and clinic. The book discusses topics such as lifestyle, nutrition and risk of gynecologic cancers, the financial impact of drug resistance, chemosensitizing agents and targeted therapies in cervical, endometrial and

Cancer Cell Chemoresistance And Chemosensitization

Cancer Cell Chemoresistance And Chemosensitization
  • Author : Kunnumakkara Ajaikumar B,Bordoloi Devivasha,Monisha Javadi
  • Publisher : World Scientific
  • Release Date : 2018-02-13
  • ISBN : 9789813208582
DOWNLOAD BOOKCancer Cell Chemoresistance And Chemosensitization

Despite the significant advances in cancer therapy made through constant evaluation and analysis of treatment aftereffects, the disease still remains one of the foremost causes of mortality worldwide killing more than 12 million people annually. The prime reason behind the failure of conventional chemotherapeutics which are used as the chief regimen in the comprehensive treatment of cancers is the development of chemoresistance. It can be either intrinsic or acquired and is primarily mediated via different key regulators like MDR, MAPK, NF-κ

Cancer Cell Chemoresistance and Chemosensitization

Cancer Cell Chemoresistance and Chemosensitization
  • Author : Ajaikumar B. Kunnumakkara,Devivasha Bordoloi,Javadi Monisha
  • Publisher : World Scientific
  • Release Date : 2018
  • ISBN : 9789813208575
DOWNLOAD BOOKCancer Cell Chemoresistance and Chemosensitization

Overcoming Drug Resistance in Gynecologic Cancers

Overcoming Drug Resistance in Gynecologic Cancers
  • Author : Anonim
  • Publisher : Elsevier
  • Release Date : 2021-09-03
  • ISBN : 9780128242995
DOWNLOAD BOOKOvercoming Drug Resistance in Gynecologic Cancers

Overcoming Drug Resistance in Gynecologic Cancers provides up-to-date information related to important gynecologic cancers and focuses on mechanisms of drug resistance, genetics, signaling, immunology, health disparities, nanotechnology, economic considerations and financial impacts. The book covers not only drug resistance but also important means to reverse resistance both in the laboratory and clinic. The book discusses topics such as lifestyle, nutrition and risk of gynecologic cancers, the financial impact of drug resistance, chemosensitizing agents and targeted therapies in cervical, endometrial and

Ovarian Cancers

Ovarian Cancers
  • Author : National Academies of Sciences, Engineering, and Medicine,Institute of Medicine,Board on Health Care Services,Committee on the State of the Science in Ovarian Cancer Research
  • Publisher : National Academies Press
  • Release Date : 2016-05-25
  • ISBN : 9780309380461
DOWNLOAD BOOKOvarian Cancers

In an era of promising advances in cancer research, there are considerable and even alarming gaps in the fundamental knowledge and understanding of ovarian cancer. Researchers now know that ovarian cancer is not a single disease-several distinct subtypes exist with different origins, risk factors, genetic mutations, biological behaviors, and prognoses. However, persistent questions have impeded progress toward improving the prevention, early detection, treatment, and management of ovarian cancers. Failure to significantly improve morbidity and mortality during the past several decades

Epigenetic Regulation in Overcoming Chemoresistance

Epigenetic Regulation in Overcoming Chemoresistance
  • Author : Chunfu Wu,Lihui Wang
  • Publisher : Academic Press
  • Release Date : 2021-06-26
  • ISBN : 9780128236857
DOWNLOAD BOOKEpigenetic Regulation in Overcoming Chemoresistance

Epigenetic Regulation in Overcoming Chemoresistance, Volume 19, explains how epigenetic agents can enhance the chemotherapy sensitivity of diverse types of cancers. The book provides a comprehensive delineation and the recent development of the scientific studies on the epigenetic regulation in enhancing chemo-sensitivity. In addition, it discusses several topics such as DNA methyltransferase inhibitors (DNMTi), Histone deacetylases inhibitors (HDACi), Histone lysine demethylases inhibitors (HDMi), Histone lysine methyltransferases inhibitors (HMTi) and drugs regulating the microRNA, long non-coding RNA (lncRNA) or RNA methylation. Finally,

Surgery for Ovarian Cancer

Surgery for Ovarian Cancer
  • Author : Robert E. Bristow,Beth Y. Karlan,Dennis S. Chi
  • Publisher : CRC Press
  • Release Date : 2019-02-21
  • ISBN : 9780429578854
DOWNLOAD BOOKSurgery for Ovarian Cancer

Updated and expanded, the third edition of Surgery for Ovarian Cancer focuses on essential techniques for the effective management of ovarian cancer. It reflects the most contemporary science and surgical applications for the management of patients with ovarian cancer and related peritoneal surface malignancies. This new edition takes a step-by-step approach and includes new intraoperative photographs and videos illustrating surgical procedures. It is principally devoted to the technical aspects of cytoreductive surgery, with chapters divided according to anatomic region. The

Stem Cells

Stem Cells
  • Author : Suchandra Chowdhury,Shyamasree Ghosh
  • Publisher : Springer Nature
  • Release Date : 2021-07-24
  • ISBN : 9789811616389
DOWNLOAD BOOKStem Cells

Stem cells hold great promise for cell therapy, tissue engineering, regenerative medicine and pharmaceutical and biotechnological applications. This book highlights the potency of stem cells, their property of self-renewal and their ability to differentiate into different cell lineages. It further describes the different markers to identify stem cells, sources, methods of isolation, culture including 2D, 3D and beyond and their cryopreservation. This is among the first books to discuss glycosylation and sialylation in stem cells. Chapters describe application of stem

The Cancer Stem Cell Niche

The Cancer Stem Cell Niche
  • Author : Susie Prof. Nilsson
  • Publisher : Academic Press
  • Release Date : 2021-01-23
  • ISBN : 9780323853262
DOWNLOAD BOOKThe Cancer Stem Cell Niche

The Cancer Stem Cell Niche, Volume Five in the Advances in Stem Cells and their Niches series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Acute lymphoblastic leukemia and the bone marrow microenvironment, Stem cell niches in bone and their roles in cancer metastasis, The role of vasculature in cancer stem cell niches, The lung cancer stem cell niche, The prostate cancer stem cell niche: Genetic drivers and

Advances in Epithelial Ovarian Cancer: Model Systems, Microenvironmental Influences, Therapy, and Origins

Advances in Epithelial Ovarian Cancer: Model Systems, Microenvironmental Influences, Therapy, and Origins
  • Author : Viive Maarika Howell,Ben Davidson,TIAN-Li WANG,Christina Annunziata
  • Publisher : Frontiers Media SA
  • Release Date : 2016-02-03
  • ISBN : 9782889197699
DOWNLOAD BOOKAdvances in Epithelial Ovarian Cancer: Model Systems, Microenvironmental Influences, Therapy, and Origins

This eBook provides a compendium of the current state-of-the-art in research tools for, and understanding of, the critical research areas in epithelial ovarian cancer (EOC) with a strong emphasis on (HG-SOC). Research areas covered include therapy response and development, microenvironmental influences and the etiology and progression of EOC. Ten articles detail established and novel in vivo and in vitro model systems. These include primary and immortalized cell culture in 2D and 3D as well as genetically engineered, transgenic, spontaneous, syngeneic,

Development of a Patient-derived Xenograft Model of Ovarian Cancer to Characterize the Chemotherapy Resistant Population

Development of a Patient-derived Xenograft Model of Ovarian Cancer to Characterize the Chemotherapy Resistant Population
  • Author : Zachary Christopher Dobbin
  • Publisher : Unknown
  • Release Date : 2014
  • ISBN : OCLC:976010431
DOWNLOAD BOOKDevelopment of a Patient-derived Xenograft Model of Ovarian Cancer to Characterize the Chemotherapy Resistant Population

Ovarian cancer while the second most common gynecologic malignancy is the most commons cause of death due to a gynecologic malignancy and the fifth most common cause of death to cancer in women. In 2014, there will be an expected 21,980 cases and 14,270 deaths. Unfortunately, the five-year survival for ovarian cancer is only 40% and this has barely increased over the past 30 years. New approaches need to be developed in order to study ovarian cancer and identify methods of overcoming chemotherapy resistance. This

Ovarian Cancer

Ovarian Cancer
  • Author : Omer Devaja,Andreas Papadopoulos
  • Publisher : BoD – Books on Demand
  • Release Date : 2018-10-24
  • ISBN : 9781789843330
DOWNLOAD BOOKOvarian Cancer

Ovarian cancer management is a rapidly changing field with new treatment agents available as a result of a greater understanding of the pathogenesis of this disease. In addition, both surgical and chemotherapeutic treatment strategies are evolving to maximise response in this disease. This book brings together leading specialists from around the world to discuss and outline a variety of new concepts in ovarian cancer, ranging from molecular biology and genetics through screening to both surgical and chemotherapeutic management.

Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance

Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance
  • Author : Andrew Freywald,Franco Vizeacoumar
  • Publisher : Academic Press
  • Release Date : 2020-12-04
  • ISBN : 9780128213117
DOWNLOAD BOOKBiological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance

Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance, Volume 12, discusses new approaches that are being undertaken to counteract tumor plasticity, understand and tackle the interactions with the microenvironment, and disrupt the rewiring of malignant cells or bypass biological mechanism of resistance by using targeted radionuclide therapies. This book provides a unique opportunity to the reader to understand the fundamental causes of drug resistance and how different approaches are applied. It is a one-stop-shop to understand why it

Fast Facts: Ovarialkarzinom

Fast Facts: Ovarialkarzinom
  • Author : C. Fotopoulou,T.J. Herzog
  • Publisher : Karger Medical and Scientific Publishers
  • Release Date : 2018-10-18
  • ISBN : 9781912776160
DOWNLOAD BOOKFast Facts: Ovarialkarzinom

In den letzten Jahren kam es zu einem noch nie dagewesenen Anstieg unseres Wissens über das Management des Ovarialkarzinoms; von Diagnose und Genetik bis hin zur Operation und neuen zielgerichteten Behandlungsmethoden. Das bedeutet, dass sich für den gut informierten Mediziner in Bezug auf die Diagnose und Behandlung von Frauen mit Ovarialkarzinom oder dem Verdacht auf Ovarialkarzinom mehrere Möglichkeiten zur sinnvollen Intervention bieten. Dieses Buch bietet eine umfassende Übersicht über alle Versorgungsebenen, fasst die aktuellen Fortschritte zusammen und stellt