Neurotherapeutics in the Era of Translational Medicine

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  • Publisher : Academic Press
  • Release : 28 November 2020
  • ISBN : 9780128172742
  • Page : 518 pages
  • Rating : 4.5/5 from 103 voters

Neurotherapeutics in the Era of Translational Medicine Book PDF summary

For the first time in history, there is now hope for treating neurological disorders that had previously been considered untreatable. The remarkable confluence of events that has heralded this is the focus of Neurotherapeutics in the Era of Translational Medicine. This anthology, written by many of the prominent scientists and researchers in the field of biotechnology, recounts the breathtaking advances that are revolutionizing treatment for disorders such as amyotrophic lateral sclerosis‎, spinal muscular atrophy, multiple sclerosis, Parkinson’s disease, myasthenia gravis, migraine, and glioblastoma. The "story behind the story" of these translational efforts is told, with authors depicting the ups and downs encountered on the path of their drug discovery and development effort. In parallel with this path, advances in identifying novel biomarkers and disease models are summarized, as are contemporary issues focusing on clinical trial design, bioethics, innovative funding strategies, and collaborations between government and academia in an effort to facilitate breakthrough treatments. The book is written by members of the biotech and pharmaceutical ecosystem for those who belong to it and aspire to become part of it. Comprehensive review on the progress of translational research in neurotherapeutics for neurologic disorders Discusses important issues in clinical trials such as design and ethical issues Written for neuroscientists, neurologists and pharmacologists

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Neurotherapeutics in the Era of Translational Medicine

Neurotherapeutics in the Era of Translational Medicine
  • Author : Richard A. Smith,Brian K. Kaspar,Clive N. Svendsen
  • Publisher : Academic Press
  • Release Date : 2020-11-28
  • ISBN : 9780128172742
DOWNLOAD BOOKNeurotherapeutics in the Era of Translational Medicine

For the first time in history, there is now hope for treating neurological disorders that had previously been considered untreatable. The remarkable confluence of events that has heralded this is the focus of Neurotherapeutics in the Era of Translational Medicine. This anthology, written by many of the prominent scientists and researchers in the field of biotechnology, recounts the breathtaking advances that are revolutionizing treatment for disorders such as amyotrophic lateral sclerosis‎, spinal muscular atrophy, multiple sclerosis, Parkinson’s disease, myasthenia

NEUROTHERAPEUTICS IN THE ERA OF TRANSLATIONAL MEDICINE.

NEUROTHERAPEUTICS IN THE ERA OF TRANSLATIONAL MEDICINE.
  • Author : RICHARD A. SMITH
  • Publisher : Elsevier
  • Release Date : 2021
  • ISBN : 9780323907262
DOWNLOAD BOOKNEUROTHERAPEUTICS IN THE ERA OF TRANSLATIONAL MEDICINE.

Drug Discovery and Development, Third Edition

Drug Discovery and Development, Third Edition
  • Author : James J. O'Donnell,John Somberg,Vincent Idemyor,James T. O'Donnell
  • Publisher : CRC Press
  • Release Date : 2019-12-13
  • ISBN : 9781351625135
DOWNLOAD BOOKDrug Discovery and Development, Third Edition

Drug Discovery and Development, Third Edition presents up-to-date scientific information for maximizing the ability of a multidisciplinary research team to discover and bring new drugs to the marketplace. It explores many scientific advances in new drug discovery and development for areas such as screening technologies, biotechnology approaches, and evaluation of efficacy and safety of drug candidates through preclinical testing. This book also greatly expands the focus on the clinical pharmacology, regulatory, and business aspects of bringing new drugs to the

Drug Discovery and Development

Drug Discovery and Development
  • Author : Vishwanath Gaitonde,Partha Karmakar,Ashit Trivedi
  • Publisher : BoD – Books on Demand
  • Release Date : 2020-03-11
  • ISBN : 9781789239751
DOWNLOAD BOOKDrug Discovery and Development

The process of drug discovery and development is a complex multistage logistics project spanned over 10-15 years with an average budget exceeding 1 billion USD. Starting with target identification and synthesizing anywhere between 10k to 15k synthetic compounds to potentially obtain the final drug that reaches the market involves a complicated maze with multiple inter- and intra-operative fields. Topics described in this book emphasize the progresses in computational applications, pharmacokinetics advances, and molecular modeling developments. In addition the book also contains

Glutathione In The Nervous System

Glutathione In The Nervous System
  • Author : Christopher Ari Shaw
  • Publisher : CRC Press
  • Release Date : 1998-02-27
  • ISBN : 1560326433
DOWNLOAD BOOKGlutathione In The Nervous System

The goal of this text is to focus readers attention on three major areas; the origin and localization of GSH in the nervous system; the multiple effects of GSH on neural health activity; and the potential for alterations on GSH status to lead to neurological damage of the type observed in amyotrophic lateral sclerosis, Parkinson's disease and other neurological disorders. The text also touches upon the additional roles of the antoxidant GSH, including possible neurotransmitter action, redox modulation of ionotropic

Neuroprotective Therapy for Stroke and Ischemic Disease

Neuroprotective Therapy for Stroke and Ischemic Disease
  • Author : Paul A. Lapchak,John H. Zhang
  • Publisher : Springer
  • Release Date : 2017-01-12
  • ISBN : 9783319453453
DOWNLOAD BOOKNeuroprotective Therapy for Stroke and Ischemic Disease

A critical and comprehensive look at current state-of-the-art scientific and translational research being conducted internationally, in academia and industry, to address new ways to provide effective treatment to victims of ischemic and hemorrhagic stroke and other ischemic diseases. Currently stroke can be successfully treated through the administration of a thrombolytic, but the therapeutic window is short and many patients are not able to receive treatment. Only about 30% of patients are "cured" by available treatments. In 5 sections, the proposed volume will

Regenerative Pharmacology

Regenerative Pharmacology
  • Author : George J. Christ,Karl-Erik Andersson
  • Publisher : Cambridge University Press
  • Release Date : 2013-04-15
  • ISBN : 9781107354739
DOWNLOAD BOOKRegenerative Pharmacology

Regenerative medicine is broadly defined as the repair or replacement of damaged cells, tissues and organs. It is a multidisciplinary effort in which technologies derive from the fields of cell, developmental and molecular biology; chemical and material sciences (i.e. nanotechnology); engineering; surgery; transplantation; immunology; molecular genetics; physiology; and pharmacology. As regenerative medicine technologies continue to evolve and expand across the boundaries of numerous scientific disciplines, they remain at the forefront of the translational research frontier with the potential to

APA Handbook of Psychopharmacology

APA Handbook of Psychopharmacology
  • Author : Suzette M. Evans,Kenneth M. Carpenter
  • Publisher : APA Handbooks in Psychology(r)
  • Release Date : 2019
  • ISBN : 1433830752
DOWNLOAD BOOKAPA Handbook of Psychopharmacology

The APA Handbook of Psychopharmacology provides working knowledge of basic pharmacology and psychopharmacology, examines psychopharmacology for treatment of various emotional and behavioral conditions, and discusses related professional and social issues.