Neuropsychiatric Disorders and Epigenetics

• Author : Dag Yasui,Jacob Peedicayil,Dennis R. Grayson
• Publisher : Academic Press
• Release Date : 2016-11-15
• ISBN : 9780128005279

Neuropsychiatric Disorders and Epigenetics is a comprehensive reference for the epigenetic basis of most common neuropsychiatric disorders. The volume is organized into chapters representing individual neuropsychiatric disorders, from addition to obesity contributed by leading experts in their respective fields. The epigenetic aspects of each disorder are discussed, in the context of the full range of epigenetic mechanisms including DNA modification, histone post-translational modification, chromatin organization and non-coding RNA. A particular emphasis is placed on potential epigenetic interventions, when the effects

• Author : Anonim
• Publisher : Academic Press
• Release Date : 2019-06-04
• ISBN : 9780128139400

Pharmacoepigenetics, Volume Eleven provides a comprehensive volume on the role of epigenetics and epigenomics in drug discovery and development, providing a detailed, but accessible, view of the field, from basic principles, to applications in disease therapeutics. Leading international researchers from across academia, clinical settings and the pharmaceutical industry discuss the influence of epigenetics and epigenomics in human pathology, epigenetic biomarkers for disease prediction, diagnosis, and treatment, current epigenetic drugs, and the application of epigenetic procedures in drug development. Throughout the

• Author : Jacob Peedicayil,Dennis R. Grayson,Dimitri Avramopoulos
• Publisher : Academic Press
• Release Date : 2021-08-16
• ISBN : 9780128235782

Epigenetics in Psychiatry, Second Edition covers all major areas of psychiatry in which extensive epigenetic research has been performed, fully encompassing a diverse and maturing field, including drug addiction, bipolar disorder, epidemiology, cognitive disorders, and the uses of putative epigenetic-based psychotropic drugs. Uniquely, each chapter correlates epigenetics with relevant advances across genomics, transcriptomics, and proteomics. The book acts as a catalyst for further research in this growing area of psychiatry. This new edition has been fully revised to address recent

• Author : Anonim
• Publisher : Academic Press
• Release Date : 2019-05-24
• ISBN : 9780128137970

Chromatin Signaling and Neurological Disorders, Volume Seven, explores our current understanding of how chromatin signaling regulates access to genetic information, and how their aberrant regulation can contribute to neurological disorders. Researchers, students and clinicians will not only gain a strong grounding on the relationship between chromatin signaling and neurological disorders, but they'll also discover approaches to better interpret and employ new diagnostic studies and epigenetic-based therapies. A diverse range of chapters from international experts speaks to the basis of chromatin

• Author : Nagy Youssef
• Publisher : Academic Press
• Release Date : 2022-02-25
• ISBN : 9780128230626

Epigenetics of Stress and Stress Disorders, Volume 31 in the Translational Epigenetics series, examines the epigenetic mechanisms involved in modifying DNA or gene expression following prolonged stress and/or trauma. Sections introduce both genetic and psychiatric foundations, including modes of epigenetic modification and gene expression that result from stress, as well as the medical knowledge required to understand stress related disorders and resilience. From here, chapters discuss epigenetic research techniques applied in recent studies, including epigenome-wide association studies (EWAS) of PTSD

• Author : Yu-Chih Shen
• Publisher : BoD – Books on Demand
• Release Date : 2016-12-14
• ISBN : 9789535128250

Schizophrenia treatment has many facets. This book begins with the glutamatergic and GABAergic hypofunctioning contribute to the schizophrenic symptoms and their current targeted therapeutics. The genetic, epigenetic, and immune etiologies of schizophrenia and their potential targeted therapeutics as approached in this book are interesting. Understanding cognitive biases and delusional circuits in schizophrenia is important; several behavioral cognitive therapies working on the reduction and avoidance of these cognitive biases are demonstrating their effectiveness. Advances in schizophrenia treatment followed, including transcranial magnetic

• Author : Uday Kishore
• Publisher : BoD – Books on Demand
• Release Date : 2013-05-15
• ISBN : 9789535110880

This book highlights the pathophysiological complexities of the mechanisms and factors that are likely to be involved in a range of neuroinflammatory and neurodegenerative diseases including Alzheimer's disease, other Dementia, Parkinson Diseases and Multiple Sclerosis. The spectrum of diverse factors involved in neurodegeneration, such as protein aggregation, oxidative stress, caspases and secretase, regulators, cholesterol, zinc, microglia, astrocytes, oligodendrocytes, etc, have been discussed in the context of disease progression. In addition, novel approaches to therapeutic interventions have also been presented. It

• Author : Koho Miyoshi,Yasushi Morimura,Kiyoshi Maeda
• Publisher : Springer Science & Business Media
• Release Date : 2010-08-09
• ISBN : 9784431538714

Around the world societies are facing growing aging populations with the concomitant increase in neuropsychiatric disorders. Neuropsychiatric disorders are organic brain diseases with psychiatric symptoms, as in Alzheimer’s and Parkinson’s diseases, that cause cognitive impairment, including dementia, amnesic syndrome, and personality–behavioral changes. As a clinical science, neuropsychiatry aims to explore the complex interrelationship between behavior and brain function from a variety of perspectives, including those of psychology, neurology, and psychiatry. This concise and updated monograph comprises the

• Author : Pedro Castelo-Branco,Carmen Jeronimo
• Publisher : Academic Press
• Release Date : 2020-08-21
• ISBN : 9780128167403

Histone Modifications in Therapy provides an in-depth analysis of the role of histone mechanisms in major diseases and the promise of targeting histone modifications for disease prevention and treatment. Here, researchers, clinicians and students will discover a thorough, evidence-based discussion of the biology of histones, the diseases engaged by aberrant histone modifications, and pathways with therapeutic potential. Expert chapter addresses the role of histone modifications across a variety of disorders, including cancer, neuropsychiatric, neurodegenerative, cardiac, metabolic, infectious, bacterial, autoimmune and

• Author : Raul Delgado-Morales
• Publisher : Springer
• Release Date : 2017-05-18
• ISBN : 9783319538891

Epigenetic mechanisms (DNA modifications, histone alterations and non-coding RNAs) are crucial for transcriptional regulation and alterations of the “physiological epigenome” are increasingly associated with human diseases. During the last decade the emerging field of neuroepigenomics have started to impact tremendously in areas such learning and memory, addiction or neurodegeneration. This expert volume covers the role of epigenetic molecular mechanism in regulation of central nervous system’s function, one of the most exciting areas of contemporary molecular neuroscience. The book describes

• Author : J. David Sweatt,Michael J. Meaney,Eric J. Nestler,Schahram Akbarian
• Publisher : Unknown
• Release Date : 2013
• ISBN : 0123914949

"Elsevier science & technology books"--P. facing t.p.

• Author : Nese Kocabasoglu,Hulya Bingol Caglayan
• Publisher : BoD – Books on Demand
• Release Date : 2019-02-27
• ISBN : 9781789854817

In this book, we focus on children with anxiety disorders and the children whose parents were diagnosed with anxiety disorders in their lifetime. The aim is to investigate the different types of anxiety disorders with different underlying mechanisms. The developmental perspective will support a better understanding of the development of anxiety disorders and transition from childhood to adulthood. We believe this book will appeal to a wide audience of practicing psychiatrists, psychologists, psychiatric nurses, social workers and mental health professionals.

• Author : Federico Durbano
• Publisher : BoD – Books on Demand
• Release Date : 2018-06-27
• ISBN : 9781789233247

In this book, with the involvement not only of clinical psychiatrists but also of neurobiologists, specific issues of psychotic disorders (mainly schizophrenia and mood disorders) are reviewed. The focus of attention ranges from therapeutics to the new frontiers of epigenetics. A special focus is on the individual reactions to psychosis (ranging from psychological ones to treatments and neurobiological basis). Because of the rapid development of neurosciences, which are showing common underling factors to different phenotypical expressions of mental illness, we

• Author : Thomas Lehner,Bruce L. Miller,Matthew W. State
• Publisher : Academic Press
• Release Date : 2016-06-07
• ISBN : 9780128005309

This foundational work comprehensively examines the current state of the genetics, genomics and brain circuitry of psychiatric and neurological disorders. It consolidates discoveries of specific genes and genomic regions associated with these conditions, the genetic and anatomic architecture of these syndromes, and addresses how recent advances in genomics are leading to a reappraisal of the biology underlying clinical neuroscience. In doing so, it critically examines the promise and limitations of these discoveries toward treatment, and to the interdisciplinary nature of

• Author : John I. Nurnberger, Jr,Wade Berrettini
• Publisher : Cambridge University Press
• Release Date : 2012-09-13
• ISBN : 9780521896498

A comprehensive, up-to-date resource providing information about genetic influences on disorders of behavior.