Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability

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  • Publisher : Academic Press
  • Release : 30 April 2016
  • ISBN : 9780128005330
  • Page : 394 pages
  • Rating : 4.5/5 from 103 voters

Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability Book PDF summary

Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability provides the latest information on Autism spectrum disorders (ASDs), the lifelong neurodevelopmental disorders that present in early childhood and affect how individuals communicate and relate to others and their surroundings. In addition, three quarters of ASD patients also manifest severe intellectual disability. Though certain genes have been implicated, ASDs remain largely a mystery, and research looking into causes and cellular deficits are crucial for better understanding of neurodevelopmental disorders. Despite the prevalence and insidious nature of this disorder, this book remains to be an extensive resource of information and background on the state of current research in the field. The book serves as a reference for this purpose, and discusses the crucial role synaptic activity plays in proper brain function. In addition, the volume discusses the neurodevelopmental synaptopathies and serves as a resource for scientists and clinicians in all biomedical science specialties. This research has been crucial for recent studies that have provided a rationale for the development of pharmacological agents able to counteract functional synaptic anomalies and potentially ameliorate some ASD symptoms. Introduces the genetic and non-genetic causes of autism and associated intellectual disabilities Describes the genes implicated in autistic spectrum disorders and their function Considers major individual genetic causes of autism, Rett syndrome, Fragile X syndrome, and other autism spectrum disorders, as well as their classification as synaptopathies Presents a thorough discussion of the clinical aspects of multiple neurodevelopmental disorders and the experimental models that exist to study their pathophysiology in vitro and in vivo, including animal models and patient-derived stem cell culture

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Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability

Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability
  • Author : Carlo Sala,Chiara Verpelli
  • Publisher : Academic Press
  • Release Date : 2016-04-30
  • ISBN : 9780128005330
DOWNLOAD BOOKNeuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability

Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability provides the latest information on Autism spectrum disorders (ASDs), the lifelong neurodevelopmental disorders that present in early childhood and affect how individuals communicate and relate to others and their surroundings. In addition, three quarters of ASD patients also manifest severe intellectual disability. Though certain genes have been implicated, ASDs remain largely a mystery, and research looking into causes and cellular deficits are crucial for better understanding of neurodevelopmental disorders.

A Time for Metabolism and Hormones

A Time for Metabolism and Hormones
  • Author : Paolo Sassone-Corsi,Yves Christen
  • Publisher : Springer
  • Release Date : 2016-04-04
  • ISBN : 9783319270692
DOWNLOAD BOOKA Time for Metabolism and Hormones

Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the

Shankopathies: Shank Protein Deficiency-Induced Synaptic Diseases

Shankopathies: Shank Protein Deficiency-Induced Synaptic Diseases
  • Author : Elodie Ey,Thomas Bourgeron,Tobias Maria Boeckers,Eunjoon Kim,Kihoon Han
  • Publisher : Frontiers Media SA
  • Release Date : 2020-03-10
  • ISBN : 9782889635672
DOWNLOAD BOOKShankopathies: Shank Protein Deficiency-Induced Synaptic Diseases

Autism Signaling Pathways

Autism Signaling Pathways
  • Author : Yu-Chih Lin,Yi-Ping Hsueh
  • Publisher : Frontiers Media SA
  • Release Date : 2021-11-23
  • ISBN : 9782889716579
DOWNLOAD BOOKAutism Signaling Pathways

Neural and Synaptic Defects in Autism Spectrum Disorders

Neural and Synaptic Defects in Autism Spectrum Disorders
  • Author : Hansen Wang,Laurie C. Doering
  • Publisher : Frontiers Media SA
  • Release Date : 2015-07-07
  • ISBN : 9782889196289
DOWNLOAD BOOKNeural and Synaptic Defects in Autism Spectrum Disorders

Autism spectrum disorders (ASDs) are a group of genetically and clinically heterogeneous neurodevelopmental disorders characterized by impaired reciprocal social interactions and communication, and restricted and repetitive patterns of behaviors and interests. Studies in genetics, neurobiology and systems biology are providing insights into the pathogenesis of ASDs. Investigation of neural and synaptic defects in ASDs not only sheds light on the molecular and cellular mechanisms that govern the function of the central nervous system, but may lead to the discovery of

Autism

Autism
  • Author : Michael Fitzgerald,Jane Yip
  • Publisher : BoD – Books on Demand
  • Release Date : 2017-04-12
  • ISBN : 9789535130796
DOWNLOAD BOOKAutism

This book opens with a discussion of neurodiversity and an elaboration of the diagnosis of autism. It then examines factors correlating with autism, including sex bias, month of birth, migration and impact of infant feeding. The next section is on the impact of autism. The neurobiology and genetic section deals with epigenetics and intracellular pathways associated with etiology. The development and behaviour section deals with proprioceptive profiles and joint attention in autism. The final section focuses on interventions including mindfulness,

Developmental-Behavioral Pediatrics E-Book

Developmental-Behavioral Pediatrics E-Book
  • Author : Heidi M Feldman, MD PhD,Nathan J Blum, MD,Ellen Roy Elias, MD,Manuel Jimenez, MD MS Faap,Terry Stancin, PhD
  • Publisher : Elsevier Health Sciences
  • Release Date : 2022-10-27
  • ISBN : 9780323809733
DOWNLOAD BOOKDevelopmental-Behavioral Pediatrics E-Book

Addressing the major advances in biomedical, psychological, social, and environmental sciences over the past decade, Developmental-Behavioral Pediatrics, 5th Edition, remains the reference of choice for professionals in a wide range of fields, including medicine and health care, education, social service, advocacy, and public policy. This foundational, pioneering resource emphasizes children's assets and liabilities, not just categorical labels. Comprehensive in scope, it offers information and guidance on normal development and behavior, psychosocial, and biologic influences on development, developmental disorders, neurodevelopmental disabilities,

Autism: Innovations and Future Directions in Psychological Research

Autism: Innovations and Future Directions in Psychological Research
  • Author : Emma Gowen,Christine M. Falter-Wagner,Laura Crane
  • Publisher : Frontiers Media SA
  • Release Date : 2022-02-14
  • ISBN : 9782889741588
DOWNLOAD BOOKAutism: Innovations and Future Directions in Psychological Research