Molecular and Genetic Basis of Renal Disease

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  • Publisher : Elsevier Health Sciences
  • Release : 11 August 2022
  • ISBN : 9781416002529
  • Page : 582 pages
  • Rating : 4.5/5 from 103 voters

Molecular and Genetic Basis of Renal Disease Book PDF summary

This companion to Brenner and Rector's The Kidney offers a state-of-the-art summary of the most recent advances in renal genetics. Molecular and Genetic Basis for Renal Disease provides the nephrologist with a comprehensive look at modern investigative tools in nephrology research today, and reviews the molecular pathophysiology of the nephron as well as the most common genetic and acquired renal diseases. A comprehensive clinical review of Medelian renal disease is also be included. Detailed review of the molecular anatomy and pathophysiology of the nephron that provides relevant basic science to consider when diagnosing and managing patients with these disorders.

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Molecular and Genetic Basis of Renal Disease

Molecular and Genetic Basis of Renal Disease
  • Author : David B. Mount,Martin R. Pollak
  • Publisher : Elsevier Health Sciences
  • Release Date : 2008
  • ISBN : 9781416002529
DOWNLOAD BOOKMolecular and Genetic Basis of Renal Disease

This companion to Brenner and Rector's The Kidney offers a state-of-the-art summary of the most recent advances in renal genetics. Molecular and Genetic Basis for Renal Disease provides the nephrologist with a comprehensive look at modern investigative tools in nephrology research today, and reviews the molecular pathophysiology of the nephron as well as the most common genetic and acquired renal diseases. A comprehensive clinical review of Medelian renal disease is also be included. Detailed review of the molecular anatomy and

The Kidney

The Kidney
  • Author : Peter D. Vize,Adrian S. Woolf,Jonathan B.L. Bard
  • Publisher : Elsevier
  • Release Date : 2003-03-14
  • ISBN : 0080521541
DOWNLOAD BOOKThe Kidney

Organogenesis of the kidney has been intensely studied for over a century. In recent years advances in molecular techniques have not only made great inroads into exploring the genetic regulation of this complex process but also began to unravel the molecular basis of many forms of congenital kidney disease. This book is a comprehensive study on these findings and the only book available with such in depth coverage of the kidney. Hundreds of color figures depicting key events in all

Genetics of Kidney Diseases

Genetics of Kidney Diseases
  • Author : Harvest F. Gu,Martin H. De Borst
  • Publisher : Frontiers Media SA
  • Release Date : 2020-05-22
  • ISBN : 9782889637379
DOWNLOAD BOOKGenetics of Kidney Diseases

Cystogenesis

Cystogenesis
  • Author : Jong Hoon Park,Curie Ahn
  • Publisher : Springer
  • Release Date : 2016-10-12
  • ISBN : 9789811020414
DOWNLOAD BOOKCystogenesis

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating mechanistic stimuli into calcium signaling. With mutations either of PKD1 or PKD2, hyper-activated renal tubular epithelial cell proliferation is observed, followed by disrupted

Genetic Diseases of the Kidney

Genetic Diseases of the Kidney
  • Author : Richard P. Lifton,Stefan Somlo,Gerhard H. Giebisch,Donald W. Seldin
  • Publisher : Academic Press
  • Release Date : 2009-02-25
  • ISBN : 0080924271
DOWNLOAD BOOKGenetic Diseases of the Kidney

Genetic approaches have revolutionized our understanding of the fundamental causes of human disease by permitting the identification of specific genes in which variation causes or contributes to susceptibility to, or protection from, disease. More than 2,000 disease genes have been identified in the last 20 years, providing important new insight into the pathophysiology of diseases in every field of medicine. Genetic Diseases of the Kidney offers expert insight into the role of genetic abnormalities in the pathogenesis of abnormal kidney function and

Genetics for Rheumatologists

Genetics for Rheumatologists
  • Author : Matthew A. Brown,Matthew Brown,Julia L. Newton,B. Paul Wordsworth
  • Publisher : Remedica
  • Release Date : 2002
  • ISBN : 9781901346312
DOWNLOAD BOOKGenetics for Rheumatologists

Annotation Trainee and practicing rheumatologists The study of disease genetics arguably began in rheumatology, with the description of the hereditary basis of alkaptonuria by Garrod in 1902, and the introduction of the concept of in-born errors of metabolism. A large proportion of the diseases seen by rheumatologists have genetic influences. The dissection of the genetic basis of rheumatic diseases has moved rapidly over the past 15 years. Increasingly, rheumatologists are being asked the question "How likely is it that my children will

Molecular Pathology

Molecular Pathology
  • Author : William B. Coleman,Gregory J. Tsongalis
  • Publisher : Academic Press
  • Release Date : 2017-11-09
  • ISBN : 9780128027875
DOWNLOAD BOOKMolecular Pathology

As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been

Kidney Development, Disease, Repair and Regeneration

Kidney Development, Disease, Repair and Regeneration
  • Author : Melissa Helen Little
  • Publisher : Academic Press
  • Release Date : 2015-08-06
  • ISBN : 9780128004388
DOWNLOAD BOOKKidney Development, Disease, Repair and Regeneration

Kidney Development, Disease, Repair and Regeneration focuses on the molecular and cellular basis of kidney development, exploring the origins of kidney lineages, the development of kidney tissue subcompartments, as well as the genetic and environmental regulation of kidney development. Special coverage is given to kidney stem cells and possible steps towards kidney repair and regeneration. Emphasis is placed on the fetal origins of postnatal renal disease and our current understanding of the molecular basis of damage and repair. Biomedical researchers

Small Molecule Therapy for Genetic Disease

Small Molecule Therapy for Genetic Disease
  • Author : Jess G. Thoene
  • Publisher : Cambridge University Press
  • Release Date : 2010-08-23
  • ISBN : 9780521517812
DOWNLOAD BOOKSmall Molecule Therapy for Genetic Disease

Thoene summarises the substantial work that has been accomplished in the treatment of inborn errors of metabolism with simple molecules. This handbook will enable interested clinician scientists to rapidly survey the field, thus ascertaining what has been done as well as future directions for therapeutic research. Its important introductory chapters discuss the infrastructure of the field. The book closely analyses the cofactors used to augment the function of defective enzymes and the compounds that are able to utilise an alternative

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 1994

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 1994
  • Author : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
  • Publisher : Unknown
  • Release Date : 1993
  • ISBN : STANFORD:36105119594690
DOWNLOAD BOOKDepartments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 1994

Departments of Labor, Health and Human Services, and Education, and Related Agencies Appropriations for Fiscal Year 1994

Departments of Labor, Health and Human Services, and Education, and Related Agencies Appropriations for Fiscal Year 1994
  • Author : United States. Congress. Senate. Committee on Appropriations. Subcommittee on Departments of Labor, Health and Human Services, Education, and Related Agencies
  • Publisher : Unknown
  • Release Date : 1993
  • ISBN : UCR:31210009487883
DOWNLOAD BOOKDepartments of Labor, Health and Human Services, and Education, and Related Agencies Appropriations for Fiscal Year 1994

Polycystic Kidney Disease

Polycystic Kidney Disease
  • Author : Jinghua Hu,Yong Yu
  • Publisher : CRC Press
  • Release Date : 2019-11-13
  • ISBN : 9780429888946
DOWNLOAD BOOKPolycystic Kidney Disease

This volume focuses on the investigatory methods applied to autosomal dominant polycystic kidney disease (ADPKD), one of the most common human genetic diseases. ADPKD is caused by mutations in PKD1 and TRPP2, two integral membrane proteins that function as receptor/ion channels in primary cilia of tubular epithelial cells. Thus, ADPKD belongs to ciliopathies, a group of disorders caused by abnormal cilia formation or function. This proposed book will cover the state-of-the-art methods ranging from molecular biology, biochemistry, electrophysiology, to

Chronic Kidney Disease

Chronic Kidney Disease
  • Author : Thomas Rath
  • Publisher : BoD – Books on Demand
  • Release Date : 2018-02-21
  • ISBN : 9789535138433
DOWNLOAD BOOKChronic Kidney Disease

Known worldwide, chronic kidney disease (CKD) is a disease that affects up to 4% of the population with increasing figures also in the developing countries. Life expectancy of patients affected by CKD is shortened compared to the overall population, and only a minority of patients reach end-stage renal disease (ESRD) with the need for dialysis or renal transplantation; death overtakes dialysis. In the 13 chapters, this book sheds light on the different aspects related to pathophysiology and clinical aspects of CKD, providing

Practical Renal Pathology, A Diagnostic Approach E-Book

Practical Renal Pathology, A Diagnostic Approach E-Book
  • Author : Donna J. Lager,Neil Abrahams
  • Publisher : Elsevier Health Sciences
  • Release Date : 2012-11-07
  • ISBN : 9781455737864
DOWNLOAD BOOKPractical Renal Pathology, A Diagnostic Approach E-Book

Practical Renal Pathology helps you apply a systematic pattern recognition approach to achieve more accurate diagnoses of both neoplastic and non-neoplastic diseases of the kidneys. This volume in the Pattern Recognition Series helps you to efficiently and confidently evaluate even the most challenging histologic specimens. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located.

Genetics for Pulmonologists

Genetics for Pulmonologists
  • Author : Jordan Prutkin,Joel Moss
  • Publisher : Remedica
  • Release Date : 2002-01-01
  • ISBN : 9781901346459
DOWNLOAD BOOKGenetics for Pulmonologists

Our understanding of the relationship between genetics and pulmonary disorders is still developing. In 1989 cloning of the gene that, when mutated, causes Cystic Fibrosis marked a great advance in the study of genetic diseases. Yet, over a decade later, understanding of how this genetic defect leads to colonization by bacteria and inflammation in the lung remains elusive. This is proving to be an engaging area of investigation for many medical professionals, with research into the effects of these genetic variations