Mesenchymal Stromal Cells

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  • Publisher : Springer Science & Business Media
  • Release : 16 January 2013
  • ISBN : 9781461457114
  • Page : 695 pages
  • Rating : 4.5/5 from 103 voters

Mesenchymal Stromal Cells Book PDF summary

Mesenchymal Stromal Cell (MSC) biology has been studied for more than 4 decades and the cells have been investigated for potential clinical applications for more than 15 years. Progress has become exponential over the past decade due mainly to the broad therapeutic potential of these cells. However, MSC studies have also been subject to controversy and increasing scrutiny as new mechanisms of action are reported and ever-expanding therapeutic applications pursued. In this book, leading authorities from all over the world, who are actively involved in this field, provide state-of-the-art knowledge of the basic biology, translational requirements and latest clinical experience with MSCs. This cutting edge book is the ideal resource for scientists and clinicians interested in pursuing an important and rapidly developing field of research that will eventually help patients and address urgent unmet medical needs. Features include: Coverage of the biology of MSCs, latest understanding of mechanisms of action, and role in tissue homeostasis and regeneration Identifying the potential of MSCs in proceeding from bench to bedside from regulatory , GMP production, ethical and safety aspects Critical analysis of clinical studies and the potential of MSCs to treat a wide variety of human diseases and tissues.

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Mesenchymal Stromal Cells

Mesenchymal Stromal Cells
  • Author : Peiman Hematti,Armand Keating
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-01-16
  • ISBN : 9781461457114
DOWNLOAD BOOKMesenchymal Stromal Cells

Mesenchymal Stromal Cell (MSC) biology has been studied for more than 4 decades and the cells have been investigated for potential clinical applications for more than 15 years. Progress has become exponential over the past decade due mainly to the broad therapeutic potential of these cells. However, MSC studies have also been subject to controversy and increasing scrutiny as new mechanisms of action are reported and ever-expanding therapeutic applications pursued. In this book, leading authorities from all over the world, who are

Mesenchymal Stromal Cells as Tumor Stromal Modulators

Mesenchymal Stromal Cells as Tumor Stromal Modulators
  • Author : Marcela Bolontrade,Mariana García
  • Publisher : Academic Press
  • Release Date : 2016-10-24
  • ISBN : 9780128031032
DOWNLOAD BOOKMesenchymal Stromal Cells as Tumor Stromal Modulators

Mesenchymal stromal/ stem cells (MSCs) represent a heterogeneous cell population with immunomodulating, tissue repairing, differentiating, migratory and angiogenic abilities, making them important tools for clinical and translational research. An understanding of the role of MSCs in modulating tumor growth provides a glimpse into their role in non-pathological tissue remodeling and potential regenerative tissue therapies. Mesenchymal Stromal Cells as Tumor Stromal Modulators is a comprehensive source for the understanding of the role of MSCs as ubiquitous connective tissue cell components, which

Mesenchymal Stem Cells

Mesenchymal Stem Cells
  • Author : Darwin J. Prockop,Donald G. Phinney,Bruce A. Bunnell
  • Publisher : Humana Press
  • Release Date : 2008-03-07
  • ISBN : 1588297713
DOWNLOAD BOOKMesenchymal Stem Cells

For over forty years, mesenchymal stem cells (MSCs) have been scrutinized and studied, garnering much attention due to their broad therapeutic efficacy. In this essential book, leaders in the field were assembled to contribute detailed methodologies for the isolation and characterization of human and rodent MSCs. Cutting edge and easy to use, this book is the perfect resource for scientists attempting to pursue this important and ever-developing field of research.

Update on Mesenchymal and Induced Pluripotent Stem Cells

Update on Mesenchymal and Induced Pluripotent Stem Cells
  • Author : Khalid Ahmed Al-Anazi
  • Publisher : BoD – Books on Demand
  • Release Date : 2020-04-22
  • ISBN : 9781789238075
DOWNLOAD BOOKUpdate on Mesenchymal and Induced Pluripotent Stem Cells

This book represents an updated overview on selected topics related to mesenchymal stem cells as well as induced pluripotent stem cells. The book is divided into three main sections that cover several topics including: sources of both stem cell types, their preparation and general properties, as well as their therapeutic indications and clinical utilization with particular attention given to their use in infectious diseases, osteoarthritis, as well as immunological disorders.

Stromal Cells

Stromal Cells
  • Author : Mani T. Valarmathi
  • Publisher : BoD – Books on Demand
  • Release Date : 2019-01-23
  • ISBN : 9781789849844
DOWNLOAD BOOKStromal Cells

Stromal cells are connective tissue cells of any organ, and they support the function of the parenchymal cells of that particular organ. Stromal/stromal stem cells are fundamentally a heterogeneous population of cells with contradictory differentiation potential depending upon their environmental niche. Stromal cell biology is not only intriguing, but equally stromal cell ontogeny in vivo remains challenging. In recent years there has been substantial advances in our understanding of stromal cell biology, especially stromal cell isolation, characterization, differentiation, and

Mesenchymal Stem Cell Assays and Applications

Mesenchymal Stem Cell Assays and Applications
  • Author : Mohan C Vemuri,Lucas G. Chase,Mahendra S. Rao
  • Publisher : Humana Press
  • Release Date : 2017-05-04
  • ISBN : 1493957791
DOWNLOAD BOOKMesenchymal Stem Cell Assays and Applications

Mesenchymal Stem Cells have seen an unprecedented level of interest in the last decade, primarily due to their relative ease of isolation, the large numbers of cells present in the adult, and the ability to propagate these cells in culture. In Mesenchymal Stem Cell Assays and Applications, expert researchers from across the globe explore the latest techniques to propagate, characterize, and engineer this special cell type. Chapters outline a set of protocols and assays used by leading investigators in the

Mesenchymal Stem Cells in Human Health and Diseases

Mesenchymal Stem Cells in Human Health and Diseases
  • Author : Ahmed El-Hashash
  • Publisher : Academic Press
  • Release Date : 2020-01-06
  • ISBN : 9780128197134
DOWNLOAD BOOKMesenchymal Stem Cells in Human Health and Diseases

Mesenchymal Stem Cells in Human Health and Diseases provides a contemporary overview of the fast-moving field of MSC biology, regenerative medicine and therapeutics. MSCs offer the potential to dramatically reduce human suffering from disease. Numerous MSC-based studies are ongoing each year, each offering hope for novel treatments in human disease. This book provides information on MSC application in well-studied human diseases and tissue repair/regeneration and recent advances in their research and treatment. These discoveries are placed within the structural

Mesenchymal Stromal Cells

Mesenchymal Stromal Cells
  • Author : Randy Morrison
  • Publisher : Unknown
  • Release Date : 2016-11-12
  • ISBN : 1634856996
DOWNLOAD BOOKMesenchymal Stromal Cells

Mesenchymal stromal cells (MSCs) are considered an important tool in tissue engineering due to their multilineage potential in vitro as in vivo beyond their capacity to produce bioactive molecules involved in tissue regeneration. MSCs are essential elements of the microenvironment because they are the precursors of all stromal cells. MSCs influence HPC functions, such as proliferation, apoptosis, and clonogenic growth, directly via cell-cell contacts or indirectly via the secretion of soluble factors. This book reviews the biology, mechanisms of action

Mesenchymal Stromal Cells

Mesenchymal Stromal Cells
  • Author : Hematti Peiman,Sowmya Viswanathan
  • Publisher : Academic Press
  • Release Date : 2016-08-11
  • ISBN : 9780128028407
DOWNLOAD BOOKMesenchymal Stromal Cells

Mesenchymal Stromal Cells: Translational Pathways to Clinical Adoption provides the latest information on the necessary steps for successful production of stem cells for a clinical trial. Written by professionals with hands-on experience in bringing MSC therapies to the clinic, and building on the biology and mechanisms of action, this unique book covers the development and production of clinical-grade products that are suitable for use in humans. From design of a cell production facility, to obtaining regulatory approval and reimbursement issues,

The Biology and Therapeutic Application of Mesenchymal Cells - Set

The Biology and Therapeutic Application of Mesenchymal Cells - Set
  • Author : Kerry Atkinson
  • Publisher : John Wiley & Sons
  • Release Date : 2017-01-17
  • ISBN : 9781118907511
DOWNLOAD BOOKThe Biology and Therapeutic Application of Mesenchymal Cells - Set

The Biology and Therapeutic Application of Mesenchymal Cells comprehensively describes the cellular and molecular biology of mesenchymal stem cells and mesenchymal stromal cells, describing their therapeutic potential in a wide variety of preclinical models of human diseases and their mechanism of action in these preclinical models. Chapters also discuss the current status of the use of mesenchymal stem and stromal cells in clinical trials in a wide range of human diseases and disorders, for many of which there are limited,

Mesenchymal Stem Cells - Basics and Clinical Application II

Mesenchymal Stem Cells - Basics and Clinical Application II
  • Author : Birgit Weyand,Massimo Dominici,Ralf Hass,Roland Jacobs,Cornelia Kasper
  • Publisher : Springer
  • Release Date : 2014-07-08
  • ISBN : 9783642379444
DOWNLOAD BOOKMesenchymal Stem Cells - Basics and Clinical Application II

Engineered MSCs from Patient-Specific iPS Cells, by Irina Eberle, Mohsen Moslem, Reinhard Henschler, Tobias Cantz Fate of Intravenously Injected Mesenchymal Stem Cells and Significance for Clinical Application, by Beate Wagner, Reinhard Henschler The Implications of Stem Cell Applications for Diseases of the Respiratory System, by Mei Ling Lim, Philipp Jungebluth, Paolo Macchiarini Potential of Mesenchymal Stem Cell Applications in Plastic and Reconstructive Surgery, by Birgit Weyand, Peter M. Vogt General Principles for the Regeneration of Bone and Cartilage, by Michael

Mesenchymal Stem Cell Therapy

Mesenchymal Stem Cell Therapy
  • Author : Lucas G. Chase,Mohan C Vemuri
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-12
  • ISBN : 9781627032001
DOWNLOAD BOOKMesenchymal Stem Cell Therapy

Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host

Hematopoietic Stem Cell Transplantation and Cellular Therapies for Autoimmune Diseases

Hematopoietic Stem Cell Transplantation and Cellular Therapies for Autoimmune Diseases
  • Author : Richard K. Burt,Dominique Farge,Milton A. Ruiz,Riccardo Saccardi,John A. Snowden
  • Publisher : CRC Press
  • Release Date : 2021-11-15
  • ISBN : 9781351364751
DOWNLOAD BOOKHematopoietic Stem Cell Transplantation and Cellular Therapies for Autoimmune Diseases

This book summarizes the global progress in medical and scientific research toward converting traditionally chronic autoimmune diseases into a drug-free reversible illness using hematopoietic stem cell transplantation (HSCT) and other cellular therapies such as T regulatory cells (Treg), mesenchymal stromal/stem cells, and chimeric antigen receptor T (CAR T) cells in order to reintroduce sustained immune tolerance. This title provides information on different types of stem cells and immune cells; post-transplant immune regeneration; cellular regulatory requirements; ethical and economic considerations;

Cells and Biomaterials in Regenerative Medicine

Cells and Biomaterials in Regenerative Medicine
  • Author : Daniel Eberli
  • Publisher : BoD – Books on Demand
  • Release Date : 2014-11-26
  • ISBN : 9789535117315
DOWNLOAD BOOKCells and Biomaterials in Regenerative Medicine

This book serves as a good starting point for anyone interested in the application of tissue engineering. It offers a colorful mix of topics, which explain the obstacles and possible solutions for TE applications. The first part covers the use of adult stem cells and their applications. The following chapters offer an insight into the development of a tailored biomaterial for organ replacement and highlight the importance of cell-biomaterial interaction. In summary, this book offers insights into a wide variety

Perinatal Stem Cells

Perinatal Stem Cells
  • Author : Anthony Atala,Kyle J. Cetrulo,Rouzbeh R. Taghizadeh,Curtis L Cetrulo,Sean Murphy
  • Publisher : Academic Press
  • Release Date : 2018-06-14
  • ISBN : 9780128120637
DOWNLOAD BOOKPerinatal Stem Cells

Perinatal Stem Cells provides researchers and clinicians with a comprehensive description of the current clinical and pre-clinical applications of stem cells derived from perinatal sources, such as amniotic fluid, placenta and placental membranes, the umbilical cord and Wharton’s jelly. It's compiled by leading experts in the field, offering readers detailed insights into sources of perinatal stem cells and their potential for disease treatment. Therapeutic applications of perinatal stem cells include the treatment of in utero and pregnancy related diseases,