Key Heterocycle Cores for Designing Multitargeting Molecules

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  • Publisher : Elsevier
  • Release : 11 June 2018
  • ISBN : 9780081021057
  • Page : 436 pages
  • Rating : 4.5/5 from 103 voters

Key Heterocycle Cores for Designing Multitargeting Molecules Book PDF summary

Key Heterocycle Cores for Designing Multitargeting Molecules provides a helpful overview of current developments in the field. Following a detailed introduction to the manipulation of heterocycle cores for the development of dual or multitargeting molecules, the book goes on to describe specific examples of such developments, focusing on compounds such as Benzimidazole, Acridine, Flavones, Thiazolidinedione and Oxazoline. Drawing on the latest developments in the field, this volume provides a valuable guide to current approaches in the design and development of molecules capable of acting on multiple targets. Adapting the heterocyclic core of a single-target molecule can facilitate its development into an agent capable of acting on multiple targets. Such multi-targeting drugs have the potential to become essential components in the design of novel, holistic treatment plans for complex diseases, making the design of such active agents an increasingly important area of research. Emphasizes the chemical development of heterocyclic nuclei, from single to multitargeting molecules Provides chapter-by-chapter coverage of the key heterocyclic compounds used in synthesizing multitargeting agents Outlines current trends and future developments in multitarget molecule design for the treatment of various diseases

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Key Heterocycle Cores for Designing Multitargeting Molecules

Key Heterocycle Cores for Designing Multitargeting Molecules
  • Author : Om Silakari
  • Publisher : Elsevier
  • Release Date : 2018-06-11
  • ISBN : 9780081021057
DOWNLOAD BOOKKey Heterocycle Cores for Designing Multitargeting Molecules

Key Heterocycle Cores for Designing Multitargeting Molecules provides a helpful overview of current developments in the field. Following a detailed introduction to the manipulation of heterocycle cores for the development of dual or multitargeting molecules, the book goes on to describe specific examples of such developments, focusing on compounds such as Benzimidazole, Acridine, Flavones, Thiazolidinedione and Oxazoline. Drawing on the latest developments in the field, this volume provides a valuable guide to current approaches in the design and development of

Advances in Heterocyclic Chemistry

Advances in Heterocyclic Chemistry
  • Author : Eric Scriven,Christopher A. Ramsden
  • Publisher : Academic Press
  • Release Date : 2020-05
  • ISBN : 9780128211687
DOWNLOAD BOOKAdvances in Heterocyclic Chemistry

Advances in Heterocyclic Chemistry is the definitive series in the field - one of great importance to organic chemists, polymer chemists, and many biological scientists. Because biology and organic chemistry increasingly intersect, the associated nomenclature also is being used more frequently in explanations. Written by established authorities in the field from around the world, this comprehensive review combines descriptive synthetic chemistry and mechanistic insight to yield an understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds.

Surfactants from Renewable Raw Materials

Surfactants from Renewable Raw Materials
  • Author : Divya Bajpai Tripathy,Anjali Gupta,Arvind Kumar Jain,Anuradha Mishra
  • Publisher : CRC Press
  • Release Date : 2021-12-22
  • ISBN : 9781000511895
DOWNLOAD BOOKSurfactants from Renewable Raw Materials

Surfactants are often completely invisible to us and yet they are present in almost every chemical that we use in our daily life. They are found in toothpastes, cosmetics, sunscreens, mayonnaise, detergents, and an array of cleaning products. Traditional surfactants are known to have adverse environmental impacts spurring research into eco-friendly and cost-effective surfactants from renewable resources. Surfactants from Renewable Raw Materials examines the class of surfactants synthesized using plant-based raw materials detailing their properties, applications, bioavailability, and biodegradability. The

Greener Synthesis of Organic Compounds

Greener Synthesis of Organic Compounds
  • Author : Ahindra Nag
  • Publisher : CRC Press
  • Release Date : 2022-03-03
  • ISBN : 9781000545128
DOWNLOAD BOOKGreener Synthesis of Organic Compounds

This book provides an interdisciplinary, integrative overview of environmental problem-solving using mild reaction conditions, green reagents, waste free and energy efficient synthesis in both industry and academic world. Discussions include a broad, integrated perspective on sustainability, integrated risk, multi-scale changes and impacts taking place within ecosystems worldwide. Features: This book serves as a reference book for scientific investigators who need to do greener synthesis of organic compounds, drugs and natural products under mild reaction condition using green reagents, eco-friendly catalysts

Science of Synthesis: Click Chemistry

Science of Synthesis: Click Chemistry
  • Author : Floris P. J. T. Rutjes
  • Publisher : Thieme
  • Release Date : 2021-11-24
  • ISBN : 9783132442153
DOWNLOAD BOOKScience of Synthesis: Click Chemistry

This reference work presents the state-of-the-art in the field of click chemistry, collecting the most useful, practical, and reliable methods. Click chemistry is a discipline that has grown rapidly since the introduction of this term by Barry Sharpless and Huisgen approximately two decades ago. Initially, click reactions mostly involved copper-catalyzed azide-alkyne cycloadditions and their applications to connect molecules, but gradually new types of click reactions were developed which also allowed a much wider range of applications throughout the chemical, biological,

Privileged Scaffolds in Medicinal Chemistry

Privileged Scaffolds in Medicinal Chemistry
  • Author : Stefan Bräse
  • Publisher : Royal Society of Chemistry
  • Release Date : 2015-11-20
  • ISBN : 9781782620303
DOWNLOAD BOOKPrivileged Scaffolds in Medicinal Chemistry

One strategy to expedite the discovery of new drugs, a process that is somewhat slow and serendipitous, is the identification and use of privileged scaffolds. This book covers the history of the discovery and use of privileged scaffolds and addresses the various classes of these important molecular fragments. The first of the benzodiazepines, a class of drugs that is powerful for treating anxiety, may not have been discovered had it not been for a chance experiment on the contents of

Green Approaches in Medicinal Chemistry for Sustainable Drug Design

Green Approaches in Medicinal Chemistry for Sustainable Drug Design
  • Author : Bimal K. Banik
  • Publisher : Elsevier
  • Release Date : 2020-03-27
  • ISBN : 9780128175934
DOWNLOAD BOOKGreen Approaches in Medicinal Chemistry for Sustainable Drug Design

Extensive experimentation and high failure rates are a well-recognised downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry reveals how medicinal and green chemistry can work together to directly address this issue. After providing essential context to the growth of green chemistry in relation to drug discovery in Part 1, the book goes on to identify a broad range of practical methods and

Green Synthetic Approaches for Biologically Relevant Heterocycles

Green Synthetic Approaches for Biologically Relevant Heterocycles
  • Author : Goutam Brahmachari
  • Publisher : Elsevier
  • Release Date : 2021-03-20
  • ISBN : 9780323851305
DOWNLOAD BOOKGreen Synthetic Approaches for Biologically Relevant Heterocycles

Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume One: Advanced Synthetic Techniques reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume One explores advanced synthetic techniques, with each chapter presenting in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles that are classified on the basis of ring-size and/