Inflammation and Immunity in Depression

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  • Publisher : Academic Press
  • Release : 23 May 2018
  • ISBN : 9780128110744
  • Page : 636 pages
  • Rating : 4.5/5 from 103 voters

Inflammation and Immunity in Depression Book PDF summary

Inflammation and Immunity in Depression: Basic Science and Clinical Applications is the first book to move beyond the established theory of cytokine-induced depression and explore the broader role the immune system plays in this devastating mood disorder. The book fully explores the most recent lines of research into this rapidly advancing field, including alterations of T-cells, the neurobiological implications of neuroinflammation and immune alterations for brain development and function, and the genetic components of neuroinflammation in depression, including the relationships between stress and inflammation that are revealing gene-environment interactions in the disorder. Combining contributions from researchers worldwide, this book provides the most comprehensive discussion available today on the involvement of the innate immune and adaptive immune systems in depressive disorder. Chapters span neuroscience, psychology, clinical applications and future directions, making this book an invaluable resource for advanced students, researchers and practitioners who need to understand the complex and varied role of inflammation and immune responses in depression. Synthesizes current knowledge of inflammation and immunity in depression, ranging from basic neuroscience research, to clinical applications in psychiatry Expands on the long-established theory of cytokine-induced depression to discuss broader involvement of the immune system Explores translational potential of targeting immune dysfunction for clinical interventions

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Inflammation and Immunity in Depression

Inflammation and Immunity in Depression
  • Author : Bernhard Baune
  • Publisher : Academic Press
  • Release Date : 2018-05-23
  • ISBN : 9780128110744
DOWNLOAD BOOKInflammation and Immunity in Depression

Inflammation and Immunity in Depression: Basic Science and Clinical Applications is the first book to move beyond the established theory of cytokine-induced depression and explore the broader role the immune system plays in this devastating mood disorder. The book fully explores the most recent lines of research into this rapidly advancing field, including alterations of T-cells, the neurobiological implications of neuroinflammation and immune alterations for brain development and function, and the genetic components of neuroinflammation in depression, including the relationships

The Inflamed Mind

The Inflamed Mind
  • Author : Edward Bullmore
  • Publisher : Picador
  • Release Date : 2018-12-31
  • ISBN : 9781250318152
DOWNLOAD BOOKThe Inflamed Mind

As seen on "CBS This Morning" Worldwide, depression will be the single biggest cause of disability in the next twenty years. But treatment for it has not changed much in the last three decades. In the world of psychiatry, time has apparently stood still...until now with Edward Bullmore's The Inflamed Mind: A Radical New Approach to Depression. A Sunday Times (London) Top Ten Bestseller In this game-changing book, University of Cambridge profressor of psychiatry Edward Bullmore reveals the breakthrough

The Immune System and Mental Health

The Immune System and Mental Health
  • Author : Hymie Anisman,Shawn Hayley,Alexander Kusnecov
  • Publisher : Academic Press
  • Release Date : 2018-07-19
  • ISBN : 9780128113523
DOWNLOAD BOOKThe Immune System and Mental Health

The Immune System and Mental Health fully investigates how immune-related cellular, molecular and anatomical changes impact mental functioning. The book combines human and animal studies to reveal immunological changes related to mental-health problems. In addition, users will find comprehensive information on new research related to the microbial composition of the gut, aka, the microbiome, and how it influences brain function and mental health. Common comorbidities with mental illness and their inherent immunological or inflammatory components are also covered. Written by

Inflammation-Associated Depression: Evidence, Mechanisms and Implications

Inflammation-Associated Depression: Evidence, Mechanisms and Implications
  • Author : Robert Dantzer,Lucile Capuron
  • Publisher : Springer
  • Release Date : 2016-12-28
  • ISBN : 9783319511528
DOWNLOAD BOOKInflammation-Associated Depression: Evidence, Mechanisms and Implications

Inflammation has invaded the field of psychiatry. The finding that cytokines are elevated in various affective and psychotic disorders brings to the forefront the necessity of identifying the precise research domain criteria (RDoCs) that inflammation is responsible for. This task is certainly the most advanced in major depressive disorders. The reason is that a dearth of clinical and preclinical studies has demonstrated that inflammation can cause symptoms of depression and conversely, cytokine antagonists can attenuate symptoms of depression in medical

Stress Challenges and Immunity in Space

Stress Challenges and Immunity in Space
  • Author : Alexander Choukèr
  • Publisher : Springer Nature
  • Release Date : 2019-11-27
  • ISBN : 9783030169961
DOWNLOAD BOOKStress Challenges and Immunity in Space

This book explains how stress – either psychological or physical – can activate and/or paralyse human innate or adaptive immunity. Adequate immunity is crucial for maintaining health, both on Earth and in space. During space flight, human physiology is specifically challenged by complex environmental stressors, which are most pronounced during lunar or interplanetary missions. Adopting an interdisciplinary approach, the book identifies the impact of these stressors – the space exposome – on immunity as a result of (dys-)functions of specific cells, organs

Textbook of Immunopsychiatry

Textbook of Immunopsychiatry
  • Author : Golam Khandaker,Neil Harrison,Edward Bullmore,Robert Dantzer
  • Publisher : Cambridge University Press
  • Release Date : 2021-09-23
  • ISBN : 9781108424042
DOWNLOAD BOOKTextbook of Immunopsychiatry

An essential book summarizing cutting-edge evidence on the role of the immune system and immunotherapies in psychiatric disorders.

Immuno-Psychiatry

Immuno-Psychiatry
  • Author : Michael Berk,Marion Leboyer,Iris E. Sommer
  • Publisher : Springer Nature
  • Release Date : 2021-08-14
  • ISBN : 9783030712297
DOWNLOAD BOOKImmuno-Psychiatry

This book presents a thorough and critical review of current knowledge on the role of immunology in major psychiatric disorders and its potential applications. The opening chapters offer general information on the immune influence of the brain to provide readers with a better understanding of the end of immune privilege. The book then examines possible underlying mechanisms leading to psychiatric disorders, from early infections to pro-inflammatory markers, stress, and immune genetic background, linking etiology and psychiatry. The third section describes

Immune Function in Sport and Exercise

Immune Function in Sport and Exercise
  • Author : Michael Gleeson
  • Publisher : Elsevier Health Sciences
  • Release Date : 2006
  • ISBN : 9780443101182
DOWNLOAD BOOKImmune Function in Sport and Exercise

This title is directed primarily towards health care professionals outside of the United States. Designed to help readers understand and evaluate the relationship between exercise, immune function and infection risk, this book presents evidence for the "J-shaped" relationship between exercise load and infection risk. It also describes the components of the human immune system and key functions that protect the body from disease, the impact of acute and chronic psychological stress on immune function, and practical guidelines for minimizing the

Depression: From Psychopathology to Pharmacotherapy

Depression: From Psychopathology to Pharmacotherapy
  • Author : J.F. Cryan,B.E. Leonard
  • Publisher : Karger Medical and Scientific Publishers
  • Release Date : 2010-11-17
  • ISBN : 9783805596060
DOWNLOAD BOOKDepression: From Psychopathology to Pharmacotherapy

Despite the availability of antidepressants for over 40 years, a substantial proportion of depressed patients do not respond adequately to treatment. Failure to respond effectively to treatment contributes to physical ill-health and psychiatric morbidity, often resulting in premature death of the depressed patient. The purpose of this volume is to consider the possible reasons for the limitations of the currently available antidepressants, to examine the advances in our understanding of the psychopathology of depression and how such knowledge may assist in

Neuroinflammation and CNS Disorders

Neuroinflammation and CNS Disorders
  • Author : Nicola Woodroofe,Sandra Amor
  • Publisher : John Wiley & Sons
  • Release Date : 2014-04-15
  • ISBN : 9781118406540
DOWNLOAD BOOKNeuroinflammation and CNS Disorders

The last decade has seen an upsurge of information on the role of immune responses in neurodegenerative disorders. In many of these diseases it is still unclear whether the innate and adaptive responses are pathogenic or play a role in repair, and thus understanding their precise roles is key to controlling these diseases by designing immune-therapeutic approaches. The connection between many neurological diseases is the realisation that the immune and nervous systems are inextricable linked, and that perturbations in this

The Oxford Handbook of Social Neuroscience

The Oxford Handbook of Social Neuroscience
  • Author : Jean Decety,John T. Cacioppo
  • Publisher : Oxford University Press
  • Release Date : 2015-04-15
  • ISBN : 9780190845759
DOWNLOAD BOOKThe Oxford Handbook of Social Neuroscience

The complexities of the brain and nervous system make neuroscience an inherently interdisciplinary pursuit, one that comprises disparate basic, clinical, and applied disciplines. Behavioral neuroscientists approach the brain and nervous system as instruments of sensation and response; cognitive neuroscientists view the same systems as a solitary computer with a focus on representations and processes. The Oxford Handbook of Social Neuroscience marks the emergence of a third broad perspective in this field. Social neuroscience emphasizes the functions that emerge through the

The Autoimmune Brain

The Autoimmune Brain
  • Author : David S. Younger
  • Publisher : Rowman & Littlefield Publishers
  • Release Date : 2019-11-10
  • ISBN : 9781538117712
DOWNLOAD BOOKThe Autoimmune Brain

There are millions of people who experience issues related to brain health--depression, attention issues, anxiety, forgetfulness, fatigue, and even chronic pain--yet can’t figure out what’s causing their problems and can’t find any relief. They may have seen a myriad of doctors, many of whom do not take their complaints seriously, or worse, turn to the easy, often inappropriate fix of antidepressants or antianxiety medications. Traditional medications, supplements, or other therapies haven’t worked. No matter what their

The Loss of Sadness

The Loss of Sadness
  • Author : Allan V. Horwitz,Jerome C. Wakefield
  • Publisher : Oxford University Press
  • Release Date : 2007-06-18
  • ISBN : 9780195313048
DOWNLOAD BOOKThe Loss of Sadness

'The Loss of Sadness' argues that the increased prevalence of major depressive disorder is due not to a genuine rise in mental disease, as many claim, but to the way that normal human sadness has been 'pathologised' since 1980.

The Neurobiological Basis of Suicide

The Neurobiological Basis of Suicide
  • Author : Yogesh Dwivedi
  • Publisher : CRC Press
  • Release Date : 2012-06-25
  • ISBN : 9781439838815
DOWNLOAD BOOKThe Neurobiological Basis of Suicide

With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they

Psychoneuroimmunology

Psychoneuroimmunology
  • Author : Robert Ader
  • Publisher : Academic Press
  • Release Date : 2014-06-28
  • ISBN : 9781483258904
DOWNLOAD BOOKPsychoneuroimmunology

Psychoneuroimmunology, Second Edition presents reports on the relationship between the nervous and immune systems. The book is divided into four sections. The first section details the role of neural structures and neurotransmitter signals in communication with the immune system. It documents the extensive neural connections with organs of the immune system; the dynamics of noradrenergic sympathetic innervation of spleen and thymus; and the evidence for immune signaling of the CNS. Part II elaborates the role of hormones in the modulation