Gene Therapy for Viral Infections

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  • Publisher : Academic Press
  • Release : 01 June 2015
  • ISBN : 9780124114524
  • Page : 392 pages
  • Rating : 4.5/5 from 103 voters

Gene Therapy for Viral Infections Book PDF summary

Gene Therapy for Viral Infections provides a comprehensive review of the broader field of nucleic acid and its use in treating viral infections. The text bridges the gap between basic science and important clinical applications of the technology, providing a systematic, integrated review of the advances in nucleic acid-based antiviral drugs and the potential advantages of new technologies over current treatment options. Coverage begins with the fundamentals, exploring varying topics, including harnessing RNAi to silence viral gene expression, antiviral gene editing, viral gene therapy vectors, and non-viral vectors. Subsequent sections include detailed coverage of the developing use of gene therapy for the treatment of specific infections, the principles of rational design of antivirals, and the hurdles that currently face the further advancement of gene therapy technology. Provides coverage of gene therapy for a variety of infections, including HBV, HCV, HIV, hemorrhagic fever viruses, and respiratory and other viral infections Bridges the gap between the basic science and the important medical applications of this technology Features a broad approach to the topic, including an essential overview and the applications of gene therapy, synthetic RNA, and other antiviral strategies that involve nucleic acid engineering Presents perspectives on the future use of nucleic acids as a novel class of antiviral drugs Arms the reader with the cutting-edge information needed to stay abreast of this developing field

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Gene Therapy for Viral Infections

Gene Therapy for Viral Infections
  • Author : Patrick Arbuthnot
  • Publisher : Academic Press
  • Release Date : 2015-06-01
  • ISBN : 9780124114524
DOWNLOAD BOOKGene Therapy for Viral Infections

Gene Therapy for Viral Infections provides a comprehensive review of the broader field of nucleic acid and its use in treating viral infections. The text bridges the gap between basic science and important clinical applications of the technology, providing a systematic, integrated review of the advances in nucleic acid-based antiviral drugs and the potential advantages of new technologies over current treatment options. Coverage begins with the fundamentals, exploring varying topics, including harnessing RNAi to silence viral gene expression, antiviral gene

Adenoviral Vectors for Gene Therapy

Adenoviral Vectors for Gene Therapy
  • Author : David T. Curiel
  • Publisher : Academic Press
  • Release Date : 2016-03-10
  • ISBN : 9780128005101
DOWNLOAD BOOKAdenoviral Vectors for Gene Therapy

Adenoviral Vectors for Gene Therapy, Second Edition provides detailed, comprehensive coverage of the gene delivery vehicles that are based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, making gene therapy a fast-growing field for research. This book presents topics ranging from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology, and the use of adenoviral vectors

Gene Therapy for HIV and Chronic Infections

Gene Therapy for HIV and Chronic Infections
  • Author : Ben Berkhout,Hildegund C.J. Ertl,Marc S. Weinberg
  • Publisher : Springer
  • Release Date : 2015-03-10
  • ISBN : 9781493924325
DOWNLOAD BOOKGene Therapy for HIV and Chronic Infections

This book centers on gene therapy and gene transfer approaches to prevent or treat chronic virus infections. The main focus is on the Big Three: human immunodeficiency virus (HIV-1), hepatitis B virus (HBV) and hepatitis C virus (HCV). Ample anti-HIV drugs are currently available in the clinic and the development of an effective combination therapy has dramatically improved the lifespan and quality of life of infected individuals. A similar trend can already be recognized for HBV and HCV: the development

Viruses in Human Gene Therapy

Viruses in Human Gene Therapy
  • Author : J. Vos
  • Publisher : Springer Science & Business Media
  • Release Date : 1995-05-31
  • ISBN : 0412631601
DOWNLOAD BOOKViruses in Human Gene Therapy

Viruses in Human Gene Therapy is a comprehensive and up to date review describing the basic biology and potential application of viruses as gene transfer reagents. It will be a useful resource for laboratories involved in any aspect of gene transfer research and will also provide an excellent introduction for those who wish to become acquainted with the field of gene therapy.

Persistent Viral Infections

Persistent Viral Infections
  • Author : R. Ahmed,Irvin Chen
  • Publisher : Wiley-Blackwell
  • Release Date : 1999
  • ISBN : UOM:39015041993448
DOWNLOAD BOOKPersistent Viral Infections

Persistent Viral Infections Edited by Rafi Ahmed Emory Vaccine Center, Atlanta, USA and Irvin S. Y. Chen UCLA School of Medicine, Los Angeles, USA During the past decade much of our attention has focused on diseases associated with viral persistence. Major breakthroughs in immunology, and the advent of molecular approaches to study pathogenesis have increased our understanding of the complex virus-host interactions that occur during viral persistence. Persistent Viral Infections focuses on: * The pathogenesis and immunology of chronic infections * Animal

Immunopharmacology

Immunopharmacology
  • Author : Manzoor M. Khan
  • Publisher : Springer Science & Business Media
  • Release Date : 2008-12-19
  • ISBN : 0387779760
DOWNLOAD BOOKImmunopharmacology

During the past decades, with the introduction of the recombinant DNA, hybridoma and transgenic technologies there has been an exponential evolution in understanding the pathogenesis, diagnosis and treatment of a large number of human diseases. The technologies are evident with the development of cytokines and monoclonal antibodies as therapeutic agents and the techniques used in gene therapy. Immunopharmacology is that area of biomedical sciences where immunology, pharmacology and pathology overlap. It concerns the pharmacological approach to the immune response in

Essential Human Virology

Essential Human Virology
  • Author : Jennifer Louten
  • Publisher : Academic Press
  • Release Date : 2016-03-29
  • ISBN : 9780128011713
DOWNLOAD BOOKEssential Human Virology

Essential Human Virology is written for the undergraduate level with case studies integrated into each chapter. The structure and classification of viruses will be covered, as well as virus transmission and virus replication strategies based upon type of viral nucleic acid. Several chapters will focus on notable and recognizable viruses and the diseases caused by them, including influenza, HIV, hepatitis viruses, poliovirus, herpesviruses, and emerging and dangerous viruses. Additionally, how viruses cause disease, or pathogenesis, will be highlighted during the

Human Herpesviruses

Human Herpesviruses
  • Author : Ann Arvin,Gabriella Campadelli-Fiume,Edward Mocarski,Patrick S. Moore,Bernard Roizman,Richard Whitley,Koichi Yamanishi
  • Publisher : Cambridge University Press
  • Release Date : 2007-08-16
  • ISBN : 9781139461641
DOWNLOAD BOOKHuman Herpesviruses

This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology