Disease Modifying Targets in Neurodegenerative Disorders

Book Disease Modifying Targets in Neurodegenerative Disorders Cover

Download book entitled Disease Modifying Targets in Neurodegenerative Disorders by Veerle Baekelandt and published by Academic Press in PDF, EPUB and Kindle. Read Disease Modifying Targets in Neurodegenerative Disorders book directly from your devices anywhere anytime. Click Download Book button to get book file. Read some info about this book below.

  • Publisher : Academic Press
  • Release : 31 March 2017
  • ISBN : 9780128052662
  • Page : 320 pages
  • Rating : 4.5/5 from 103 voters

Disease Modifying Targets in Neurodegenerative Disorders Book PDF summary

Disease-Modifying Targets in Neurodegenerative Disorders: Paving the Way for Disease-Modifying Therapies examines specific neurodegenerative disorders in comprehensive chapters written by experts in the respective fields. Each chapter contains a summary of the disease management field, subsequently elaborating on the molecular mechanisms and promising new targets for disease-modifying therapies. This overview is ideal for neuroscientists, biomedical researchers, medical doctors, and caregivers, not only providing readers with a summary of the way patients are treated today, but also offering a glance at the future of neurodegenerative disorder treatment. Provides a comprehensive overview of how key proteins in neurodegenerative disorders can be used as targets to modify disease progress Summarizes how patients are treated today, providing a glance at future disease management Includes intelligible and informative information that is perfect for non-specialists, medical practitioners, and scientists Written and peer reviewed by outstanding scientists in their respective fields

DOWNLOAD BOOK

Disease-Modifying Targets in Neurodegenerative Disorders

Disease-Modifying Targets in Neurodegenerative Disorders
  • Author : Veerle Baekelandt,Evy Lobbestael
  • Publisher : Academic Press
  • Release Date : 2017-03-31
  • ISBN : 9780128052662
DOWNLOAD BOOKDisease-Modifying Targets in Neurodegenerative Disorders

Disease-Modifying Targets in Neurodegenerative Disorders: Paving the Way for Disease-Modifying Therapies examines specific neurodegenerative disorders in comprehensive chapters written by experts in the respective fields. Each chapter contains a summary of the disease management field, subsequently elaborating on the molecular mechanisms and promising new targets for disease-modifying therapies. This overview is ideal for neuroscientists, biomedical researchers, medical doctors, and caregivers, not only providing readers with a summary of the way patients are treated today, but also offering a glance at

Molecular Targets in Protein Misfolding and Neurodegenerative Disease

Molecular Targets in Protein Misfolding and Neurodegenerative Disease
  • Author : Pierfausto Seneci
  • Publisher : Academic Press
  • Release Date : 2014-10-07
  • ISBN : 9780128004999
DOWNLOAD BOOKMolecular Targets in Protein Misfolding and Neurodegenerative Disease

Aimed at "drug discoverers" – i.e. any scientist who is interested in neurodegenerative diseases in general, and in finding disease-modifying treatments in particular – the first edition of Molecular Targets in Protein Misfolding and Neurodegenerative Disease will contain both a detailed, discipline-specific coverage (paragraphs on medicinal chemistry, on clinical and preclinical characterization of compounds in development, on target identification and validation, on genetic factors influencing a pathology, etc.) and a drug discovery-oriented, overall evaluation of each target (validation, druggability, existing leads,

Drug Design and Discovery in Alzheimer’s Disease

Drug Design and Discovery in Alzheimer’s Disease
  • Author : Atta-ur-Rahman,Muhammad Iqbal Choudhary
  • Publisher : Elsevier
  • Release Date : 2015-06-27
  • ISBN : 9780128039601
DOWNLOAD BOOKDrug Design and Discovery in Alzheimer’s Disease

Drug Design and Discovery in Alzheimer’s Disease includes expert reviews of recent developments in Alzheimer's disease (AD) and neurodegenerative disease research. Originally published by Bentham as Frontiers in Drug Design and Discovery, Volume 6and now distributed by Elsevier, this compilation of the sixteen articles, written by leading global researchers, focuses on key developments in the understanding of the disease at molecular levels, identification and validation of molecular targets, as well as innovative approaches towards drug discovery, development, and delivery.

Neuroprotection in Alzheimer's Disease

Neuroprotection in Alzheimer's Disease
  • Author : Illana Gozes
  • Publisher : Academic Press
  • Release Date : 2016-12-30
  • ISBN : 9780128037126
DOWNLOAD BOOKNeuroprotection in Alzheimer's Disease

Neuroprotection in Alzheimer’s Disease offers a translational point-of-view from both basic and clinical standpoints, putting it on the cusp for further clinical development with its emphasis on nerve cell protection, including the accumulation of knowledge from failed clinical trials and new advances in disease management. This book brings together the latest findings, both basic, and clinical, under the same cover, making it easy for the reader to obtain a complete overview of the state-of-the-field and beyond. Alzheimer's disease is

TDP-43 and Neurodegeneration

TDP-43 and Neurodegeneration
  • Author : Vijay Kumar,Manoj Kumar Jaiswal
  • Publisher : Academic Press
  • Release Date : 2021-10-23
  • ISBN : 9780128204405
DOWNLOAD BOOKTDP-43 and Neurodegeneration

Aggregates of the TAR DNA binding protein 43 (TDP-43), are hallmark features of the neurodegenerative diseases Amyotrophic Lateral Sclerosis (ALS) and frontotemporal dementia (FTD), with overlapping clinical, genetic and pathological features. TDP-43 and Neurodegeneration: From Bench to Bedside summarizes new findings in TDP-43 pathobiology and proteinopathies. The book summarizes TDP-43’s structure, function, biology, misfolding, aggregation, pathogenesis and therapeutics. It includes autophagy-mediated therapy, role of stress granule, novel genetic, cell culture-based models, systems biology for precision medicine, development of stem cells

Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders

Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders
  • Author : Adeboye Adejare
  • Publisher : Academic Press
  • Release Date : 2016-09-20
  • ISBN : 9780128028117
DOWNLOAD BOOKDrug Discovery Approaches for the Treatment of Neurodegenerative Disorders

Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders: Alzheimer’s Disease examines the drug discovery process for neurodegenerative diseases by focusing specifically on Alzheimer’s Disease and illustrating the paradigm necessary to ensure future research and treatment success. The book explores diagnosis, epidemiology, drug discovery strategies, current therapeutics, and much more to provide a holistic approach to the discovery, development, and treatment of Alzheimer’s Disease. Through its coverage of the latest research in targeted drug design, preclinical studies,

Biometals in Neurodegenerative Diseases

Biometals in Neurodegenerative Diseases
  • Author : Anthony R. White,Michael Aschner,Lucio G. Costa,Ashley I. Bush
  • Publisher : Academic Press
  • Release Date : 2017-04-28
  • ISBN : 9780128045633
DOWNLOAD BOOKBiometals in Neurodegenerative Diseases

Biometals in Neurodegenerative Diseases: Mechanisms and Therapeutics is an authoritative and timely resource bringing together the major findings in the field for ease of access to those working in the field or with an interest in metals and their role in brain function, disease, and as therapeutic targets. Chapters cover metals in Alzheimer’s Disease, Parkinson’s Disease, Motor Neuron Disease, Autism and lysosomal storage disorders. This book is written for academic researchers, clinicians and advanced graduate students studying or

Emerging Drugs and Targets for Alzheimer's Disease

Emerging Drugs and Targets for Alzheimer's Disease
  • Author : Ana Martinez
  • Publisher : Unknown
  • Release Date : 2010-05-07
  • ISBN : 1849730458
DOWNLOAD BOOKEmerging Drugs and Targets for Alzheimer's Disease

A comprehensive 2-volume complete set that collects some of the most promising examples of new drugs currently under pharmaceutical development that will reach the Alzheimer's drug market over the next few years as disease-modifying therapeutics.

Neurodegenerative Diseases

Neurodegenerative Diseases
  • Author : Jagan A Pillai PhD
  • Publisher : Oxford University Press
  • Release Date : 2016-10-17
  • ISBN : 9780190233570
DOWNLOAD BOOKNeurodegenerative Diseases

As the global population ages the impact of neurodegenerative diseases like Alzheimer's disease and Parkinson's disease are significant forces in shaping human health and quality of life in the 21st century. Insights into understanding these diseases, and knowing how to treat them are major frontiers of scientific research. Neurodegenerative Diseases: Unifying Principles is the result of a conceptual revolution over the last decade in our understanding of neurodegenerative diseases as sharing unifying features. There is an increasing appreciation of the

Emerging Drugs and Targets for Multiple Sclerosis

Emerging Drugs and Targets for Multiple Sclerosis
  • Author : Ana Martinez
  • Publisher : Royal Society of Chemistry
  • Release Date : 2019-06-28
  • ISBN : 9781788014502
DOWNLOAD BOOKEmerging Drugs and Targets for Multiple Sclerosis

Multiple sclerosis (MS) is a complex disease with a presumed autoimmune aetiology and few current effective treatments. Disease modifying therapies focus on the altering the natural course of relapsing and remitting MS, targeting the inflammatory response. Other targets involve tacking the cause of the disease – demyelination of axons through remyelination therapies. Due to several recent breakthroughs in the understanding of the pathophysiology of MS new targets for remyelination and immunomodulation are rapidly emerging. This book provides a comprehensive overview of

Neurotrophins Biodelivery to CNS: Innovative Approaches for Disease-Modifying Therapy

Neurotrophins Biodelivery to CNS: Innovative Approaches for Disease-Modifying Therapy
  • Author : Viviana Triaca,Bruno Pietro Imbimbo,Robert Nistico
  • Publisher : Frontiers Media SA
  • Release Date : 2022-06-01
  • ISBN : 9782889763030
DOWNLOAD BOOKNeurotrophins Biodelivery to CNS: Innovative Approaches for Disease-Modifying Therapy

Neurodegenerative Diseases

Neurodegenerative Diseases
  • Author : Nagehan Ersoy Tunalı
  • Publisher : BoD – Books on Demand
  • Release Date : 2021-01-20
  • ISBN : 9781838801496
DOWNLOAD BOOKNeurodegenerative Diseases

Neurodegenerative diseases represent a very large group of heterogeneous disorders affecting specific subtypes of neurons in the brain. This book contributes insight both to the awareness of the brain and its neurodegenerative states. The chapters present current knowledge regarding genetics, molecular mechanisms, and new therapeutic strategies against neurodegenerative disorders. The book is intended to serve as a source to aid clinicians and researchers in the field, and also life science readers to increase their understanding and awareness of the clinical

Molecular Mechanisms of Neurodegenerative Diseases

Molecular Mechanisms of Neurodegenerative Diseases
  • Author : Marie-Francoise Chesselet
  • Publisher : Springer Science & Business Media
  • Release Date : 2000-10-19
  • ISBN : 9781592590063
DOWNLOAD BOOKMolecular Mechanisms of Neurodegenerative Diseases

With the unprecedented identification of new mutation mechanisms in neurodegenerative diseases and the emergence of common mechanisms among diseases that were once considered unrelated, neurobiologists are poised for the development of new therapies based on high throughput screenings and a better understanding of the molecular and cellular mechanisms leading to neurodegeneration. In Molecular Mechanisms of Neurodegenerative Diseases, Marie-Francoise Chesselet, MD, PhD, and a panel of leading researchers and neurologists from industry and academia critically review the most recent advances from

Sigma Receptors: Their Role in Disease and as Therapeutic Targets

Sigma Receptors: Their Role in Disease and as Therapeutic Targets
  • Author : Sylvia B. Smith,Tsung-Ping Su
  • Publisher : Springer
  • Release Date : 2017-03-16
  • ISBN : 9783319501741
DOWNLOAD BOOKSigma Receptors: Their Role in Disease and as Therapeutic Targets

Originally confused with opioid receptors and then orphan receptors with no biological function, Sigma Receptors are now recognized as relevant to many degenerative diseases with remarkable potential as therapeutic targets. In this text, new information about the structure of sigma 1 receptor, its binding sites are provided as well as its expression in many cell types. It’s putative role in degenerative neuronal diseases including amyotrophic lateral sclerosis, Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, pain, drug addiction and

Handbook of Research on Critical Examinations of Neurodegenerative Disorders

Handbook of Research on Critical Examinations of Neurodegenerative Disorders
  • Author : Uddin, Md. Sahab,Amran, Md. Shah
  • Publisher : IGI Global
  • Release Date : 2018-07-31
  • ISBN : 9781522552833
DOWNLOAD BOOKHandbook of Research on Critical Examinations of Neurodegenerative Disorders

Neurodegeneration is a key feature of several diseases that are referred to as neurodegenerative diseases. The process of neurodegeneration is not well-understood so the diseases that stem from it have, as yet, no cures. As such, studying the effects of these disorders can provide insight into the treatment, prevention, and future opportunities and challenges in this growing field. The Handbook of Research on Critical Examinations of Neurodegenerative Disorders is a critical scholarly resource that provides an extensive explanation of various