Clinical and Translational Science

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  • Publisher : Academic Press
  • Release : 25 November 2016
  • ISBN : 9780128021118
  • Page : 808 pages
  • Rating : 4.5/5 from 103 voters

Clinical and Translational Science Book PDF summary

Clinical and Translational Science: Principles of Human Research, Second Edition, is the most authoritative and timely resource for the broad range of investigators taking on the challenge of clinical and translational science, a field that is devoted to investigating human health and disease, interventions, and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. This updated second edition has been prepared with an international perspective, beginning with fundamental principles, experimental design, epidemiology, traditional and new biostatistical approaches, and investigative tools. It presents complete instruction and guidance from fundamental principles, approaches, and infrastructure, especially for human genetics and genomics, human pharmacology, research in special populations, the societal context of human research, and the future of human research. The book moves on to discuss legal, social, and ethical issues, and concludes with a discussion of future prospects, providing readers with a comprehensive view of this rapidly developing area of science. Introduces novel physiological and therapeutic strategies for engaging the fastest growing scientific field in both the private sector and academic medicine Brings insights from international leaders into the discipline of clinical and translational science Addresses drug discovery, drug repurposing and development, innovative and improved approaches to go/no-go decisions in drug development, and traditional and innovative clinical trial designs

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Clinical and Translational Science

Clinical and Translational Science
  • Author : David Robertson,Gordon H. Williams
  • Publisher : Academic Press
  • Release Date : 2016-11-25
  • ISBN : 9780128021118
DOWNLOAD BOOKClinical and Translational Science

Clinical and Translational Science: Principles of Human Research, Second Edition, is the most authoritative and timely resource for the broad range of investigators taking on the challenge of clinical and translational science, a field that is devoted to investigating human health and disease, interventions, and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. This updated second edition has been prepared with an international perspective, beginning with fundamental principles, experimental design, epidemiology, traditional and

Clinical and Translational Science

Clinical and Translational Science
  • Author : David Robertson
  • Publisher : Academic Press
  • Release Date : 2016-10-17
  • ISBN : 0128021012
DOWNLOAD BOOKClinical and Translational Science

"Clinical and Translational Science: Principles of Human Research, Second Edition, " is the most authoritative and timely resource for the broad range of investigators taking on the challenge of clinical and translational science, a field that is devoted to investigating human health and disease, interventions, and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. This updated second edition has been prepared with an international perspective, beginning with fundamental principles, experimental design, epidemiology, traditional and

The CTSA Program at NIH

The CTSA Program at NIH
  • Author : Institute of Medicine,Board on Health Sciences Policy,Committee to Review the Clinical and Translational Science Awards Program at the National Center for Advancing Translational Sciences
  • Publisher : National Academies Press
  • Release Date : 2013-10-09
  • ISBN : 9780309284745
DOWNLOAD BOOKThe CTSA Program at NIH

In 2006 the National Institutes of Health (NIH) established the Clinical and Translational Science Awards (CTSA) Program, recognizing the need for a new impetus to encourage clinical and translational research. At the time it was very difficult to translate basic and clinical research into clinical and community practice; making it difficult for individual patients and communities to receive its benefits. Since its creation the CTSA Program has expanded, with 61 sites spread across the nation's academic health centers and other institutions, hoping

Principles of Translational Science in Medicine

Principles of Translational Science in Medicine
  • Author : Martin Wehling
  • Publisher : Academic Press
  • Release Date : 2021-08-01
  • ISBN : 9780128204962
DOWNLOAD BOOKPrinciples of Translational Science in Medicine

Principles of Translational Science in Medicine: From Bench to Bedside, Third Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing number of new chemical/biological entities (NCEs or NBEs) as

Pharmaceutical Medicine and Translational Clinical Research

Pharmaceutical Medicine and Translational Clinical Research
  • Author : Divya Vohora,Gursharan Singh
  • Publisher : Academic Press
  • Release Date : 2017-11-14
  • ISBN : 9780128020982
DOWNLOAD BOOKPharmaceutical Medicine and Translational Clinical Research

Pharmaceutical Medicine and Translational Clinical Research covers clinical testing of medicines and the translation of pharmaceutical drug research into new medicines, also focusing on the need to understand the safety profile of medicine and the benefit-risk balance. Pharmacoeconomics and the social impact of healthcare on patients and public health are also featured. It is written in a clear and straightforward manner to enable rapid review and assimilation of complex information and contains reader-friendly features. As a greater understanding of these

Clinical and Translational Perspectives on WILSON DISEASE

Clinical and Translational Perspectives on WILSON DISEASE
  • Author : Nanda Kerkar,Eve A Roberts
  • Publisher : Academic Press
  • Release Date : 2018-09-18
  • ISBN : 9780128105337
DOWNLOAD BOOKClinical and Translational Perspectives on WILSON DISEASE

Clinical and Translational Perspectives on Wilson Disease brings together the genetics, cell and structural biology of Wilson Disease into one contemporary, easy to navigate handbook. Created to meet the diverse needs of the clinical and research communities surrounding Wilson Disease, this reference provides a worldwide approach that is concise and translational. Specifically, it provides a basis for clinicians to appreciate ‘basic science’ aspects of Wilson disease, presenting a guide for researchers to understand the clinical disorder on which their research

Clinical and Translational Science

Clinical and Translational Science
  • Author : David Robertson,Gordon H. Williams
  • Publisher : Academic Press
  • Release Date : 2009-03-02
  • ISBN : 0080920195
DOWNLOAD BOOKClinical and Translational Science

Clinical or translational science is the field of study devoted to investigating human health and disease, interventions and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. New molecular tools and diagnostic technologies based on clinical and translational research have lead to a better understanding of human disease and the application of new therapeutics for enhanced health. Clinical and Translational Science is designed as the most authoritative and modern resource for the broad range

Progress in Molecular Biology and Translational Science

Progress in Molecular Biology and Translational Science
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2019-03-22
  • ISBN : 9780128177396
DOWNLOAD BOOKProgress in Molecular Biology and Translational Science

Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part A, Volume 162 in the Progress in Molecular Biology and Translational Science series provides informative monographs on a variety of research topics related to Glycans and glycosaminoglycans as clinical biomarkers and therapeutics. Topics in this update include Glycan-based Biomarkers for Diagnosis of Cancers and Other Diseases: Past, Present and Future, Desialylation in Diseases and its Application in Diagnostic and Therapeutic Development, Proteoglycans as Miscommunication Biomarkers for Cancer Diagnosis, Fucosylation in Cancer

Progress in Molecular Biology and Translational Science

Progress in Molecular Biology and Translational Science
  • Author : David B. Teplow
  • Publisher : Academic Press
  • Release Date : 2018-10-16
  • ISBN : 9780128162361
DOWNLOAD BOOKProgress in Molecular Biology and Translational Science

Progress in Molecular Biology and Translational Science, Volume 159, provides the most topical, informative and exciting monographs available on a wide variety of research topics related to prions, viruses, bacteria and eukaryotes. The series includes in-depth knowledge on molecular biological aspects of organismal physiology, along with insights on how this knowledge may be applied to understand and ameliorate human disease. New chapters in this release discuss timely topics, such as Targeting recently deorphanized GPR83 for the treatment of infection, stress, and

Translational Regenerative Medicine

Translational Regenerative Medicine
  • Author : Anthony Atala,Julie Allickson
  • Publisher : Academic Press
  • Release Date : 2014-12-01
  • ISBN : 9780124104570
DOWNLOAD BOOKTranslational Regenerative Medicine

Translational Regenerative Medicine is a reference book that outlines the life cycle for effective implementation of discoveries in the dynamic field of regenerative medicine. By addressing science, technology, development, regulatory, manufacturing, intellectual property, investment, financial, and clinical aspects of the field, this work takes a holistic look at the translation of science and disseminates knowledge for practical use of regenerative medicine tools, therapeutics, and diagnostics. Incorporating contributions from leaders in the fields of translational science across academia, industry, and government,

Translational Stroke Research

Translational Stroke Research
  • Author : Paul A. Lapchak,John H. Zhang
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-03-22
  • ISBN : 9781441995308
DOWNLOAD BOOKTranslational Stroke Research

This volume sets a basis for effective translational research. Authored by experts in the field of translational stroke research, each chapter specifically addresses one or more components of preclinical stroke research. The emphasis is placed on target identification and drug development using state-of-the-art in vitro and in vivo assays, in combination with in vitro toxicology assays, AMDE and clinical design.

Translational Bioinformatics and Systems Biology Methods for Personalized Medicine

Translational Bioinformatics and Systems Biology Methods for Personalized Medicine
  • Author : Qing Yan
  • Publisher : Academic Press
  • Release Date : 2017-04-18
  • ISBN : 9780128043882
DOWNLOAD BOOKTranslational Bioinformatics and Systems Biology Methods for Personalized Medicine

Translational Bioinformatics and Systems Biology Methods for Personalized Medicine introduces integrative approaches in translational bioinformatics and systems biology to support the practice of personalized, precision, predictive, preventive, and participatory medicine. Through the description of important cutting-edge technologies in bioinformatics and systems biology, readers may gain an essential understanding of state-of-the-art methodologies. The book discusses topics such as the challenges and tasks in translational bioinformatics; pharmacogenomics, systems biology, and personalized medicine; and the applicability of translational bioinformatics for biomarker discovery, epigenomics,

Translating Expertise

Translating Expertise
  • Author : Marisa L. Conte
  • Publisher : Rowman & Littlefield
  • Release Date : 2016-08-29
  • ISBN : 9781442262683
DOWNLOAD BOOKTranslating Expertise

Translating Expertise: The Librarian’s Role in Translational Research provides background and context on the CTSA program. Case studies detail routes to librarian involvement in translational research, including collection development, relationships with researchers and administrators, instruction and training, data management, and team science.

Broadly Engaged Team Science in Clinical and Translational Research

Broadly Engaged Team Science in Clinical and Translational Research
  • Author : Debra J. Lerner,Marisha E. Palm,Thomas W. Concannon
  • Publisher : Springer Nature
  • Release Date : 2022
  • ISBN : 9783030830281
DOWNLOAD BOOKBroadly Engaged Team Science in Clinical and Translational Research

Despite the large U.S. investment in health science, and the vast and growing body of peer-reviewed research findings it has produced, a compelling body of evidence suggests that research too often has been slow, inefficient, and fallen short of desired impacts on health. A key question is how research might be changed to be more innovative, less wasteful, and more responsive to unmet health needs. One emerging response within clinical and translational science is to advance an approach that

Translational Medicine: Tools And Techniques

Translational Medicine: Tools And Techniques
  • Author : Aamir Shahzad
  • Publisher : Academic Press
  • Release Date : 2015-11-24
  • ISBN : 9780128034941
DOWNLOAD BOOKTranslational Medicine: Tools And Techniques

Translational Medicine: Tools and Techniques provides a standardized path from basic research to the clinic and brings together various policy and practice issues to simplify the broad interdisciplinary field. With discussions from academic and industry leaders at international institutions who have successfully implemented translational medicine techniques and tools in various settings, readers will be guided through implementation strategies relevant to their own needs and institutions. The book also addresses regulatory processes in USA, EU, Japan and China. By providing details