Chromatin Regulation and Dynamics

• Author : Anita Göndör
• Publisher : Academic Press
• Release Date : 2016-10-25
• ISBN : 9780128034026

Chromatin Regulation and Dynamics integrates knowledge on the dynamic regulation of primary chromatin fiber with the 3D nuclear architecture, then connects related processes to circadian regulation of cellular metabolic states, representing a paradigm of adaptation to environmental changes. The final chapters discuss the many ways chromatin dynamics can synergize to fundamentally contribute to the development of complex diseases. Chromatin dynamics, which is strategically positioned at the gene-environment interface, is at the core of disease development. As such, Chromatin Regulation and

• Author : Ralf Blossey
• Publisher : CRC Press
• Release Date : 2017-08-04
• ISBN : 9781351646819

An invaluable resource for computational biologists and researchers from other fields seeking an introduction to the topic, Chromatin: Structure, Dynamics, Regulation offers comprehensive coverage of this dynamic interdisciplinary field, from the basics to the latest research. Computational methods from statistical physics and bioinformatics are detailed whenever possible without lengthy recourse to specialized techniques.

• Author : Amelia J. Hodges
• Publisher : Unknown
• Release Date : 2017
• ISBN : OCLC:1057284841

In a eukaryotic cell, DNA is packaged into chromatin, a highly dynamic and highly regulated structure. Chromatin is composed of nucleosome subunits, comprised of an octamer of histone proteins wrapped by DNA. Histone proteins are highly conserved among species, and also show a high degree of post-translational modification. In this work, we sought to better understand the roles of histone residues, histone domains, and histone modification in chromatin regulation and dynamics using Saccharomyces cerevisiae as a model eukaryote. In part

• Author : Ralf Blossey
• Publisher : CRC Press
• Release Date : 2017-08-04
• ISBN : 9781498729383

An invaluable resource for computational biologists and researchers from other fields seeking an introduction to the topic, Chromatin: Structure, Dynamics, Regulation offers comprehensive coverage of this dynamic interdisciplinary field, from the basics to the latest research. Computational methods from statistical physics and bioinformatics are detailed whenever possible without lengthy recourse to specialized techniques.

• Author : Renato Paro,Ueli Grossniklaus,Raffaella Santoro,Anton Wutz
• Publisher : Springer Nature
• Release Date : 2021-03-23
• ISBN : 9783030686703

This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading

• Author : Suming Huang,Michael D Litt,C. Ann Blakey
• Publisher : Academic Press
• Release Date : 2015-10-19
• ISBN : 9780128004715

Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a

• Author : Célia Baroux,Marian Bemer
• Publisher : Unknown
• Release Date : 2018
• ISBN : 1493973185

• Author : Colin Logie,Tobias Aurelius Knoch
• Publisher : BoD – Books on Demand
• Release Date : 2020-01-29
• ISBN : 9781789844924

Genomics has gathered broad public attention since Lamarck put forward his top-down hypothesis of 'motivated change' in 1809 in his famous book "Philosophie Zoologique" and even more so since Darwin published his famous bottom-up theory of natural selection in "The Origin of Species" in 1859. The public awareness culminated in the much anticipated race to decipher the sequence of the human genome in 2002. Over all those years, it has become apparent that genomic DNA is compacted into chromatin with a dedicated 3D

• Author : Beth Ann Tamburini,University of Colorado at Denver and Health Sciences Center
• Publisher : Unknown
• Release Date : 2006
• ISBN : OCLC:226524175

• Author : Rachel Miriam Zunder
• Publisher : Unknown
• Release Date : 2011
• ISBN : OCLC:858268734

In all eukaryotic organisms, DNA is packaged into chromatin, which controls gene expression and genomic stability. The chromatin landscape is dynamic and responds to environmental signals to direct different cellular programs. Chromatin architecture is regulated by a network of structural and enzymatic proteins that interact with histones to alter nucleosome composition. In my dissertation, I examined 1) the interaction between histone chaperones and newly synthesized histones during nucleosome assembly and 2) the interplay between canonical histone isotypes, histone variants, and histone modifications.

• Author : Sara Farrona,Rafal Archacki,Juan Armando Casas-Mollano,Iva Mozgová
• Publisher : Frontiers Media SA
• Release Date : 2021-07-27
• ISBN : 9782889710911

• Author : Tapas K. Kundu,Dipak Dasgupta
• Publisher : Springer
• Release Date : 2007-03-05
• ISBN : 1402054653

This book includes a collection of articles with the broad theme of disease connection to chromatin structure and function. It elaborates on the molecular pharmacology of the drugs targeting chromatin structure and its components. The book contains up-to-date information about the chromatin structure and chromatin related diseases and drug functions. This work is the first endeavor to present different aspects encompassing the above theme.

• Author : José Luis Sardina,Justin Brumbaugh,Bruno Di Stefano
• Publisher : Frontiers Media SA
• Release Date : 2021-10-20
• ISBN : 9782889715107

• Author : J. Zlatanova,S. H. Leuba
• Publisher : Gulf Professional Publishing
• Release Date : 2004
• ISBN : 0444515941

Biological processes that replicate, preserve and use the genetic information encoded in DNA must operate in the context of chromatin, a highly organized complex of DNA and proteins. These proteins do not merely package the DNA in the tiny volume of the nucleus, but impart the structure the ability to change according to the requirements of the specific process the DNA is involved in. Moreover, chromatin structure is used by the cell to control the activity of DNA. In this

• Author : Marcus Govert Johannes Maria Wijgerde
• Publisher : Unknown
• Release Date : 1998
• ISBN : OCLC:496240164