Cell Polarity in Development and Disease

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  • Publisher : Academic Press
  • Release : 14 November 2017
  • ISBN : 9780128125915
  • Page : 236 pages
  • Rating : 4.5/5 from 103 voters

Cell Polarity in Development and Disease Book PDF summary

Cell Polarity in Development and Disease offers insights into the basic molecular mechanisms of common diseases that arise as a result of a loss of ordered organization and intrinsic polarity. Included are diseases affecting highly polarized epithelial tissues in the lung and kidney, as well as loss and gain of cell polarity in the onset and progression of cancer. This book provides a basic resource for understanding the biology of polarity, offering a starting point for those thinking of targeting cell polarity for translational medical research. Provides basic science understanding of cell polarity disease and development Covers diseases affecting polarized epithelial tissues in the lung and kidney, also covering the progression of cancer Includes historical context of cell polarity research for potential future breakthroughs

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Cell Polarity in Development and Disease

Cell Polarity in Development and Disease
  • Author : Douglas W Houston
  • Publisher : Academic Press
  • Release Date : 2017-11-14
  • ISBN : 9780128125915
DOWNLOAD BOOKCell Polarity in Development and Disease

Cell Polarity in Development and Disease offers insights into the basic molecular mechanisms of common diseases that arise as a result of a loss of ordered organization and intrinsic polarity. Included are diseases affecting highly polarized epithelial tissues in the lung and kidney, as well as loss and gain of cell polarity in the onset and progression of cancer. This book provides a basic resource for understanding the biology of polarity, offering a starting point for those thinking of targeting

Cell Polarity 2

Cell Polarity 2
  • Author : Klaus Ebnet
  • Publisher : Springer
  • Release Date : 2015-02-24
  • ISBN : 9783319144665
DOWNLOAD BOOKCell Polarity 2

This work provides a state-of-the art overview on the most relevant aspects of cell polarity. Volume 2 discusses the physiological and pathophysiological relevance of cell polarity. It especially focuses on pathophysiological conditions in which one or several aspects of cell polarity are impaired, and in which a loss of cell polarity possibly contributes to disease (e.g. epithelial-to-mesenchymal transition in cancer, role of polarity proteins in cancer). Both volumes are intended for professors, group leaders and researchers in cell biology as

The Role of Cell-polarity in Development and Disease

The Role of Cell-polarity in Development and Disease
  • Author : Payman Samavarchi-Tehrani
  • Publisher : Unknown
  • Release Date : 2013
  • ISBN : OCLC:1032963230
DOWNLOAD BOOKThe Role of Cell-polarity in Development and Disease

Planar Cell Polarity in Kidney Development and Disease

Planar Cell Polarity in Kidney Development and Disease
  • Author : H. L. Brzoska
  • Publisher : Unknown
  • Release Date : 2017
  • ISBN : OCLC:1065374691
DOWNLOAD BOOKPlanar Cell Polarity in Kidney Development and Disease

Planar Cell Polarity in Kidney Development and Disease

Planar Cell Polarity in Kidney Development and Disease
  • Author : Hortensja Łucja Brzóska
  • Publisher : Unknown
  • Release Date : 2017
  • ISBN : OCLC:1166900086
DOWNLOAD BOOKPlanar Cell Polarity in Kidney Development and Disease

Amphibian Models of Development and Disease

Amphibian Models of Development and Disease
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2021-05-30
  • ISBN : 9780128168349
DOWNLOAD BOOKAmphibian Models of Development and Disease

Amphibian Models of Development and Disease, Volume 145 in the Current Topics in Developmental Biology series, highlights new advances in the field written by an international board of experts. New chapters in this release include Building a ciliated epithelium: Transcriptional regulation and radial intercalation of multiciliated cells, Biomechanics of Amphibian Morphogenesis, Planar cell polarity during neural tube closure, Xenopus neural crest and its relevance to human disease, Endoderm organogenesis, From egg to embryo in marsupial frogs, Evo-devo lessons from the analysis

Planar Cell Polarity

Planar Cell Polarity
  • Author : Kursad Turksen
  • Publisher : Humana Press
  • Release Date : 2017-04-30
  • ISBN : 1493959069
DOWNLOAD BOOKPlanar Cell Polarity

Planar cell polarity (PCP), or the alignment of a collection of cells within a cell sheet, has proven, over time, to be vital in not only normal development but also in disease states. In Planar Cell Polarity: Methods and Protocols, expert researchers in the field present a number of detailed and well-designed protocols used successfully in their labs around the world. As a volume in the highly successful Methods in Molecular BiologyTM series, the chapters contain introductions to their respective

Cystogenesis

Cystogenesis
  • Author : Jong Hoon Park,Curie Ahn
  • Publisher : Springer
  • Release Date : 2016-10-12
  • ISBN : 9789811020414
DOWNLOAD BOOKCystogenesis

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating mechanistic stimuli into calcium signaling. With mutations either of PKD1 or PKD2, hyper-activated renal tubular epithelial cell proliferation is observed, followed by disrupted

Cell Polarity

Cell Polarity
  • Author : Keith E. Mostov
  • Publisher : Unknown
  • Release Date : 2017-03-31
  • ISBN : 1621821455
DOWNLOAD BOOKCell Polarity

Most animal cells are polarized, with structurally and functionally distinct regions. This polarization facilitates processes such as differentiation and morphogenesis, directional cell migration, nerve impulse transmission, and transport of molecules across tissues. The dysregulation of these processes can lead to developmental disorders and is a feature of many cancers. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology reviews our understanding of the molecular mechanisms involved in establishing and maintaining cell polarity,

Cellular Adhesion in Development and Disease

Cellular Adhesion in Development and Disease
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2015-02-27
  • ISBN : 9780124078895
DOWNLOAD BOOKCellular Adhesion in Development and Disease

Cell adhesion is a fundamental determinant of embryonic development and organogenesis. Cellular Adhesion in Development and Disease, volume 112 in Current Topics in Developmental Biology, comprehensively surveys current developments in understanding how adhesion systems affect organismal development. Topics covered include nectins, nectin-like molecules, and afadin in development; cadherin adhesion, signaling, and morphogenesis; endothelial cell junctions; epidermal development and barrier formation; and more. This book surveys current understanding of how adhesion systems affect organismal development

The Cadherin Superfamily

The Cadherin Superfamily
  • Author : Shintaro T. Suzuki,Shinji Hirano
  • Publisher : Springer
  • Release Date : 2016-06-02
  • ISBN : 9784431560333
DOWNLOAD BOOKThe Cadherin Superfamily

This book presents an overview of the entire field of cadherin research and provides the current basic concept of cadherins. Cadherins have been widely accepted as key regulators of animal development and physiological functions, and it also has become clear that they play essential roles in various human diseases. With contributions by leading scientists, the book covers various aspects of the cadherin superfamily including the history of cadherin research, basic properties of classical cadherins as well as non-classical cadherins, cadherin-associated

Planar Cell Polarity During Development

Planar Cell Polarity During Development
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2012-12-31
  • ISBN : 9780123948007
DOWNLOAD BOOKPlanar Cell Polarity During Development

This new volume of Current Topics in Developmental Biology covers the area of Planar Cell Polarity with contributions from an international board of authors. The 12 chapters provide a comprehensive set of reviews covering such topics as PCP in Zebra fish, the role of Dishevelled in PCP regulation, and PCP in axon pathfinding. Covers the area of planar cell polarity International board of authors 12 chapters provide a comprehensive set of reviews covering such topics as planar cell polarity in Zebrafish, the

Molecular Biology of the Cell

Molecular Biology of the Cell
  • Author : Bruce Alberts
  • Publisher : Unknown
  • Release Date : 2004
  • ISBN : 0815332181
DOWNLOAD BOOKMolecular Biology of the Cell

Extracellular Matrix Degradation

Extracellular Matrix Degradation
  • Author : William C. Parks,Robert Mecham
  • Publisher : Springer Science & Business Media
  • Release Date : 2011-04-07
  • ISBN : 9783642168611
DOWNLOAD BOOKExtracellular Matrix Degradation

Regulated turnover of extracellular matrix (ECM) is an important component of tissue homeostasis. In recent years, the enzymes that participate in, and control ECM turnover have been the focus of research that touches on development, tissue remodeling, inflammation and disease. This volume in the Biology of Extracellular Matrix series provides a review of the known classes of proteases that degrade ECM both outside and inside the cell. The specific EMC proteases that are discussed include cathepsins, bacterial collagenases, matrix metalloproteinases,

Adherens Junctions: from Molecular Mechanisms to Tissue Development and Disease

Adherens Junctions: from Molecular Mechanisms to Tissue Development and Disease
  • Author : Tony Harris
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-06-07
  • ISBN : 9789400741867
DOWNLOAD BOOKAdherens Junctions: from Molecular Mechanisms to Tissue Development and Disease

Cell–cell adhesion is fundamental for the development and homeostasis of animal tissues and organs. Adherens junctions (AJs) are the best understood cell-cell adhesion complexes. In this volume, a group of internationally recognized experts reviews AJ biology over a wide range of organization; from atoms to molecules, to protein complexes, molecular networks, cells, tissues, and overall animal development. AJs have also been an integral part of animal evolution, and play central roles in cancer development, pathogen infection and other diseases.