Biofabrication

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  • Publisher : MIT Press
  • Release : 14 September 2021
  • ISBN : 9780262542968
  • Page : 216 pages
  • Rating : 4.5/5 from 103 voters

Biofabrication Book PDF summary

How engineered materials and machines powered by living biological cells can tackle technological challenges in medicine, agriculture, and global security. You are a biological machine whose movement is powered by skeletal muscle, just as a car is a machine whose movement is powered by an engine. If you can be built from the bottom up with biological materials, other machines can be as well. This is the conceptual starting point for biofabrication, the act of building with living cells--building with biology in the same way we build with synthetic materials. In this volume in the MIT Press Essential Knowledge series, Ritu Raman offers an accessible introduction to biofabrication, arguing that it can address some of our greatest technological challenges. After presenting the background information needed to understand the emergence and evolution of biofabrication and describing the fundamental technology that enables building with biology, Raman takes deep dives into four biofabrication applications that have the potential to affect our daily lives: tissue engineering, organs-on-a-chip, lab-grown meat and leather, and biohybrid machines. Organs-on-a-chip (devices composed of miniature model tissues), for example, could be used to test new medicine and therapies, and lab-grown meat could alleviate environmental damage done by animal farming. She shows that biological materials have abilities synthetic materials do not, including the ability to adapt dynamically to their environments. Exploring the principles of biofabrication, Raman tells us, should help us appreciate the beauty, adaptiveness, and persistence of the biological machinery that drives our bodies and our world.

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Biofabrication

Biofabrication
  • Author : Ritu Raman
  • Publisher : MIT Press
  • Release Date : 2021-09-14
  • ISBN : 9780262542968
DOWNLOAD BOOKBiofabrication

How engineered materials and machines powered by living biological cells can tackle technological challenges in medicine, agriculture, and global security. You are a biological machine whose movement is powered by skeletal muscle, just as a car is a machine whose movement is powered by an engine. If you can be built from the bottom up with biological materials, other machines can be as well. This is the conceptual starting point for biofabrication, the act of building with living cells--building with

Biofabrication

Biofabrication
  • Author : Gabor Forgacs,Wei Sun
  • Publisher : William Andrew
  • Release Date : 2013-03-18
  • ISBN : 9781455730049
DOWNLOAD BOOKBiofabrication

Biofabrication is a practical guide to the novel, inherently cross-disciplinary scientific field that focuses on biomanufacturing processes and a related range of emerging technologies. These processes and technologies ultimately further the development of products that may involve living (cells and/or tissues) and nonliving (bio-supportive proteins, scaffolds) components. The book introduces readers to cell printing, patterning, assembling, 3D scaffold fabrication, cell/tissue-on-chips as a coherent micro-/nano-fabrication toolkit. Real-world examples illustrate how to apply biofabrication techniques in areas such as

Biofabrication

Biofabrication
  • Author : Andrew M. Blakely,Jacquelyn Y. Schell,Adam P. Rago,Peter R. Chai,Anthony P. Napolitano,Jeffrey R. Morgan
  • Publisher : Elsevier Inc. Chapters
  • Release Date : 2013-03-18
  • ISBN : 9780128090558
DOWNLOAD BOOKBiofabrication

Scaffold-free tissue engineering approaches take advantage of cell–cell interactions, specifically the phenomena of self-assembly and self-sorting. By using micro-molded nonadhesive hydrogels, mono-dispersed cells can be seeded and directed to form spheroids as well as more complex shapes. These complex structures, including toroids, honeycombs, and loop-ended dogbones, bypass the critical diffusion distance required to maintain cell viability in culture over time. In addition, the formed microtissues are amenable to assays that analyze the self-assembly dynamics, the sorting of two different

Biofabrication

Biofabrication
  • Author : Yi Cheng,Yi Liu,Benjamin D. Liba,Reza Ghodssi,Gary W. Rubloff,William E. Bentley,Gregory F. Payne
  • Publisher : Elsevier Inc. Chapters
  • Release Date : 2013-03-18
  • ISBN : 9780128090596
DOWNLOAD BOOKBiofabrication

Integrated circuits transformed our lives, and the potential for integrating biology with devices promises even greater transformations. A key question is how to effectively interface biological and microfabricated systems. Our approach is to “biofabricate” the biology-device interface using biological materials and mechanisms. Here, we review recent progress on three biofabrication approaches: the use of stimuli-responsive materials to recognize device-imposed electrical inputs to direct the assembly (i.e., to electrodeposit) of hydrogels; the use of enzymes to build structure by conjugating

Biofabrication and 3D Tissue Modeling

Biofabrication and 3D Tissue Modeling
  • Author : Dong-Woo Cho
  • Publisher : Royal Society of Chemistry
  • Release Date : 2019-01-02
  • ISBN : 9781788016643
DOWNLOAD BOOKBiofabrication and 3D Tissue Modeling

3D tissue modelling is an emerging field used for the investigation of disease mechanisms and drug development. The two key drivers of this upsurge in research lie in its potential to offer a way to reduce animal testing with respect to biotoxicity analysis, preferably on physiology recapitulated human tissues and, additionally, provides an alternative approach to regenerative medicine. Integrating physics, chemistry, materials science, and stem cell and biomedical engineering, this book provides a complete foundation to this exciting, and interdisciplinary

Essentials of 3D Biofabrication and Translation

Essentials of 3D Biofabrication and Translation
  • Author : Anthony Atala,James J Yoo
  • Publisher : Academic Press
  • Release Date : 2015-07-17
  • ISBN : 9780128010150
DOWNLOAD BOOKEssentials of 3D Biofabrication and Translation

Essentials of 3D Biofabrication and Translation discusses the techniques that are making bioprinting a viable alternative in regenerative medicine. The book runs the gamut of topics related to the subject, including hydrogels and polymers, nanotechnology, toxicity testing, and drug screening platforms, also introducing current applications in the cardiac, skeletal, and nervous systems, and organ construction. Leaders in clinical medicine and translational science provide a global perspective of the transformative nature of this field, including the use of cells, biomaterials, and

Biofabrication and Biopolymeric Materials Innovation for Musculoskeletal Tissue Regeneration

Biofabrication and Biopolymeric Materials Innovation for Musculoskeletal Tissue Regeneration
  • Author : Farnaz Ghorbani,Chaozong Liu,Derek H. Rosenzweig,Megan Elin Cooke
  • Publisher : Frontiers Media SA
  • Release Date : 2022-04-25
  • ISBN : 9782889749898
DOWNLOAD BOOKBiofabrication and Biopolymeric Materials Innovation for Musculoskeletal Tissue Regeneration

Kenzan Method for Scaffold-Free Biofabrication

Kenzan Method for Scaffold-Free Biofabrication
  • Author : Koichi Nakayama
  • Publisher : Springer Nature
  • Release Date : 2021-01-22
  • ISBN : 9783030586881
DOWNLOAD BOOKKenzan Method for Scaffold-Free Biofabrication

This is the first book about the “Kenzan” method for scaffold-free biofabrication, which does not rely on biomaterials as scaffolds to ensure correct multicellular spheroid positioning for building three dimensional construct only made from cells. The book explains the basic principles and concepts of the microneedle-based (“Kenzan”) method of building surgically-implantable tissue constructs using robotic cell spheroid-based three-dimensional bioprinting, a novel technology that opens up unique opportunities for the bioengineering of tissues and organs. First book on the novel Kenzan