Antimicrobial Peptides in Gastrointestinal Diseases

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  • Publisher : Academic Press
  • Release : 06 June 2018
  • ISBN : 9780128143209
  • Page : 186 pages
  • Rating : 4.5/5 from 103 voters

Antimicrobial Peptides in Gastrointestinal Diseases Book PDF summary

Antimicrobial peptides (AMPs), including cathelicidins and defensins are host defence peptides that carry out multiple roles in the gastrointestinal (GI) tract. Antimicrobial Peptides in Gastrointestinal Diseases presents knowledge about the physiological functions and pharmacological actions of AMPs in inflammation, cancer, and further infection of the GI tract. The book provides coverage from the basic research to clinical application for GI diseases. Current research and development of AMPs is presented, opening the way for further work on these peptides, not only in the context of GI diseases, but also for similar pathologies in other organs. AMPs are key to the regulation of human microbiome and second line defence in the GI mucosa, prevent colonization of pathogens and modulation of innate response to invading pathogens, and modify immunological reactions during inflammatory processes and oncogenic development in the GI mucosa. More importantly, AMPs possess diversified anti-microbial actions against various infectious diseases in the GI tract. With these physiological functions and pharmacological actions, AMPs have significant potential as therapeutic agents for the treatment of inflammation, cancer and further infection in the GI tract. Provides an overview of AMPs, particularly cathelicidin and defensin, in different diseases Covers inflammation and ulcer repair in the stomach and colon and carcinogenesis in the GI tract Presents AMP information and knowledge in a concise manner Gives useful information on all aspects of AMPs Promotes research on AMPs and their development as drugs, from bench, to clinical application

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Antimicrobial Peptides in Gastrointestinal Diseases

Antimicrobial Peptides in Gastrointestinal Diseases
  • Author : Chi Hin Cho
  • Publisher : Academic Press
  • Release Date : 2018-06-06
  • ISBN : 9780128143209
DOWNLOAD BOOKAntimicrobial Peptides in Gastrointestinal Diseases

Antimicrobial peptides (AMPs), including cathelicidins and defensins are host defence peptides that carry out multiple roles in the gastrointestinal (GI) tract. Antimicrobial Peptides in Gastrointestinal Diseases presents knowledge about the physiological functions and pharmacological actions of AMPs in inflammation, cancer, and further infection of the GI tract. The book provides coverage from the basic research to clinical application for GI diseases. Current research and development of AMPs is presented, opening the way for further work on these peptides, not only

Lasso Peptides

Lasso Peptides
  • Author : Yanyan Li,Séverine Zirah,Sylvie Rebuffat
  • Publisher : Springer
  • Release Date : 2014-10-21
  • ISBN : 9781493910106
DOWNLOAD BOOKLasso Peptides

Lasso peptides form a growing family of fascinating ribosomally-synthesized and post-translationally modified peptides produced by bacteria. They contain 15 to 24 residues and share a unique interlocked topology that involves an N-terminal 7 to 9-residue macrolactam ring where the C-terminal tail is threaded and irreversibly trapped. The ring results from the condensation of the N-terminal amino group with a side-chain carboxylate of a glutamate at position 8 or 9, or an aspartate at position 7, 8 or 9. The trapping of the tail involves bulky amino acids located

Crohn's Disease and Ulcerative Colitis

Crohn's Disease and Ulcerative Colitis
  • Author : Daniel C. Baumgart
  • Publisher : Springer
  • Release Date : 2017-03-01
  • ISBN : 9783319337036
DOWNLOAD BOOKCrohn's Disease and Ulcerative Colitis

This new edition is a unique combined resource for physicians and scientists addressing the needs of both groups. In addition to stimulating exchange and collaboration and shortening the path between discovery and application of new knowledge, the book helps clinicians understand new therapeutic concepts from their origins. The volume serves as a comprehensive guide to the current diagnostic modalities, including enhanced imaging techniques such as MRI and CT enterography, virtual colonoscopy, ultrasound, and endomicroscopy, as well as conventional and complex

Nanostructures for Antimicrobial Therapy

Nanostructures for Antimicrobial Therapy
  • Author : Anton Ficai,Alexandru Mihai Grumezescu
  • Publisher : Elsevier
  • Release Date : 2017-05-29
  • ISBN : 9780323461511
DOWNLOAD BOOKNanostructures for Antimicrobial Therapy

Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials,

Antimicrobial Peptides and Human Disease

Antimicrobial Peptides and Human Disease
  • Author : William Shafer
  • Publisher : Springer Science & Business Media
  • Release Date : 2006-10-05
  • ISBN : 9783540299165
DOWNLOAD BOOKAntimicrobial Peptides and Human Disease

Microbes are in our midst soon after birth. Thankfully, the number of harmless (and often beneficial) microbes far outnumber those that would do us harm. Our ability to ward-off pathogens in our environment, including those that can colonize our exterior and/or interior surfaces, depends on the integrative action of the innate and adaptive immunity systems. This volume of CTMI, entitled Antimicrobial Peptides and Human Disease, is dedicated to the role of antimicrobial peptides (AMPs) in the innate host defense

New Weapons to Control Bacterial Growth

New Weapons to Control Bacterial Growth
  • Author : Tomas G. Villa,Miguel Vinas
  • Publisher : Springer
  • Release Date : 2016-03-24
  • ISBN : 9783319283685
DOWNLOAD BOOKNew Weapons to Control Bacterial Growth

Written by specialists in the different fields, this book presents new perspectives and insights into strategies and weapons to fight microbial infections. It also reviews the “state of the art” of alternative treatment approaches and new therapeutic agents to deal with infections caused by multidrug-resistant microorganisms. In an era of accumulated resistance to current antibiotics, it is vital that this is undertaken without further delay. Aspects discussed include the control of RNA synthesis, the use of bacteriocins or enzybiotics (bacteriophages

Lessons in Immunity

Lessons in Immunity
  • Author : Loriano Ballarin,Matteo Cammarata
  • Publisher : Academic Press
  • Release Date : 2016-04-08
  • ISBN : 9780128032534
DOWNLOAD BOOKLessons in Immunity

Lessons in Immunity: From Single-cell Organisms to Mammals stems from the activity of the Italian Association of Developmental and Comparative Immunobiology (IADCI), represented by the editors. This book is presented as a series of short overviews that report on the current state of various relevant fields of immunobiology from an evolutionary perspective. The overviews are written by authors directly involved in the research, and most are members of the IADCI or have otherwise been involved in the related research for

Antimicrobial Cationic Peptides—Advances in Research and Application: 2012 Edition

Antimicrobial Cationic Peptides—Advances in Research and Application: 2012 Edition
  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release Date : 2012-12-26
  • ISBN : 9781481603072
DOWNLOAD BOOKAntimicrobial Cationic Peptides—Advances in Research and Application: 2012 Edition

Antimicrobial Cationic Peptides—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Antimicrobial Cationic Peptides. The editors have built Antimicrobial Cationic Peptides—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Antimicrobial Cationic Peptides in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Antimicrobial Cationic

Antimicrobial Peptides

Antimicrobial Peptides
  • Author : Katsumi Matsuzaki
  • Publisher : Springer
  • Release Date : 2019-04-12
  • ISBN : 9789811335884
DOWNLOAD BOOKAntimicrobial Peptides

This book presents an overview of antimicrobial peptides (AMPs), their mechanisms of antimicrobial action, other activities, and various problems that must still be overcome regarding their clinical application. Divided into four major parts, the book begins with a general overview of AMPs (Part I), and subsequently discusses the various mechanisms of antimicrobial action and methods for researching them (Part 2). It then addresses a range of activities other than antimicrobial action, such as cell penetration, antisepsis, anticancer, and immunomodulatory activities (Part 3),

Health and the Gut

Health and the Gut
  • Author : William Olds
  • Publisher : CRC Press
  • Release Date : 2014-08-04
  • ISBN : 9781498701266
DOWNLOAD BOOKHealth and the Gut

This title includes a number of Open Access chapters. The study of the intestinal ecosystem of bacteria in the human gut—the gut microbiome—is a new field that is rapidly evolving. This book serves as an introduction to some of the new and exciting research that is being done in this field. Included are chapters that examine the following: • Gut microbiome’s roles in the pathogenesis of obesity and autoimmune disease • The effect of nutrition on the richness of

Immunodeficiency and Disease

Immunodeficiency and Disease
  • Author : A.D.B Webster
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • ISBN : 9789400912755
DOWNLOAD BOOKImmunodeficiency and Disease

The AIDS epidemic has popularized immune deficiency and has led to a rapid increase in the funding for research into the effect of viruses on immunity. There is now a real possibility of finding out whether some of the rare, so-called 'primary' immunodeficiency syndromes of children and adults, first described in the 1950s, may have a viral aetiology. Most of these syndromes have already been extensively reviewed more than once over the past 10 years, and their diagnosis and management is

Adrenomedullin

Adrenomedullin
  • Author : Alfredo Martínez,Frank Cuttitta
  • Publisher : IOS Press
  • Release Date : 1998
  • ISBN : 9051993609
DOWNLOAD BOOKAdrenomedullin

Adrenomedullin is a recently discovered peptide hormone which involved in many physiological and pathological processes. This book reviews all the information available on this intriguing molecule, covering topics as diverse as blood pressure regulation, growth of tumours and normal cells, the central nervous system, and comparative studies from sharks to mammals. An international group of experts has contributed to this volume which will be of interest to professionals, researchers, and those who will benefit from a broad review of the

Nutraceutical Proteins and Peptides in Health and Disease

Nutraceutical Proteins and Peptides in Health and Disease
  • Author : Yoshinori Mine,Fereidoon Shahidi
  • Publisher : CRC Press
  • Release Date : 2005-09-29
  • ISBN : 9781420028836
DOWNLOAD BOOKNutraceutical Proteins and Peptides in Health and Disease

Reports of the beneficial health effects of some peptides have begun to make their way into the scientific literature. Peptides can act as immunomodulators, and have been shown to have a positive influence on calcium absorption, and on regulation of serum cholesterol. A number of peptides may also possess antimicrobial properties that enhance the body's defense mechanisms, and others may produce inhibitory effects for angiotensin-I-converting enzyme (ACE), leading to novel treatments for blood pressure conditions, heart failure, and diabetes. Modern

Pathogenesis of Periodontal Diseases

Pathogenesis of Periodontal Diseases
  • Author : Nagihan Bostanci,Georgios N. Belibasakis
  • Publisher : Springer
  • Release Date : 2017-09-25
  • ISBN : 9783319537375
DOWNLOAD BOOKPathogenesis of Periodontal Diseases

This book aims to provide clinicians with a refined understanding of the biology that underlies periodontal diseases, thereby offering a sound basis for improved clinical decision making with regard to prevention strategies, diagnosis, and therapy. All significant aspects of periodontal pathogenesis are covered, including the roles played by the oral microbiome and biofilms, bacterial virulence factors, cells of the immune system, matrix metalloproteinases, proinflammatory and osteolytic cytokines, genetic factors, and antimicrobial peptides. Periodontal diseases are among the most common infectious

Emerging Nanotechnologies in Immunology

Emerging Nanotechnologies in Immunology
  • Author : Ranjita Shegokar,Eliana B. Souto
  • Publisher : William Andrew
  • Release Date : 2018-05-17
  • ISBN : 9780323401135
DOWNLOAD BOOKEmerging Nanotechnologies in Immunology

Emerging Nanotechnologies in Immunology: The Design, Applications and Toxicology of Nanopharmaceuticals and Nanovaccines aims to deliver a systematic and comprehensive review of data concerning the nature of interaction and nano-related risks between the nanopharmaceuticals currently in the pipeline of S&T development for skin, ocular and nasal drug delivery, including absorption, toxicity, and the ability to distribute after systemic exposure. The book's contributors address a representative set of the broad spectrum of nanopharmaceutics presently being used, including cationic lipid nanoparticles,