A Paradigm Shift to Prevent and Treat Alzheimer s Disease

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  • Publisher : Academic Press
  • Release : 18 July 2017
  • ISBN : 9780128122792
  • Page : 290 pages
  • Rating : 4.5/5 from 103 voters

A Paradigm Shift to Prevent and Treat Alzheimer s Disease Book PDF summary

A Paradigm Shift to Prevent and Treat Alzheimer’s Disease: From Monotargeting Pharmaceuticals to Pleiotropic Plant Polyphenols is the first book to systematically exhibit the powerful pleiotropic pharmacological effects on Alzheimer’s disease of plant-based compounds from ancient foods that humans have been consuming safely with substantial health benefits for thousands of years. These plant-based compounds include curcuminoids from turmeric, resveratrol from red wine and grape seed extract from other grape products, epigallocatechin-gallate (EGCG) from green tea, and oleocanthal and oleuropein from olive oil, in addition to a special extract, EGb 761, from the leaves of Ginkgo biloba, the oldest living species of tree on earth. This book also presents a new analytical framework that convincingly favors a multi-targeting ("pleiotropic") approach to the prevention and treatment of complex chronic diseases, in contrast to the mono-targeting of the pharmaceutical model. A Paradigm Shift to Prevent and Treat Alzheimer’s Disease is a unique and exciting resource for pharmaceutical scientists, pharmacologists, neurologists, general practitioners, research scientists in various medical and life sciences, healthcare professionals in clinical and executive positions, conventional medical schools, schools of naturopathic medicine, healthcare and medical journalists, executives in both national public healthcare systems and private insurers, and informed general readers. Presents carefully compiled evidence supporting the need to shift from pharmaceutical-based mono-targeting to plant polyphenol-based pleiotropic targeting for the prevention and treatment of Alzheimer’s disease Includes valuable tables that aggregate pleiotropic pharmacological effects of the plant polyphenols on Alzheimer’s disease-related pathogenic hallmarks Highlights regulatory aspects and discusses the challenges and potential solutions with respect to bioavailability of certain plant polyphenols

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A Paradigm Shift to Prevent and Treat Alzheimer's Disease

A Paradigm Shift to Prevent and Treat Alzheimer's Disease
  • Author : Howard Friel,Sally A. Frautschy
  • Publisher : Academic Press
  • Release Date : 2017-07-18
  • ISBN : 9780128122792
DOWNLOAD BOOKA Paradigm Shift to Prevent and Treat Alzheimer's Disease

A Paradigm Shift to Prevent and Treat Alzheimer’s Disease: From Monotargeting Pharmaceuticals to Pleiotropic Plant Polyphenols is the first book to systematically exhibit the powerful pleiotropic pharmacological effects on Alzheimer’s disease of plant-based compounds from ancient foods that humans have been consuming safely with substantial health benefits for thousands of years. These plant-based compounds include curcuminoids from turmeric, resveratrol from red wine and grape seed extract from other grape products, epigallocatechin-gallate (EGCG) from green tea, and oleocanthal and

ABC's of Alzheimers Disease

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  • Author : Bruce Bauer
  • Publisher : Covenant Books, Inc.
  • Release Date : 2019-05-23
  • ISBN : 9781643009490
DOWNLOAD BOOKABC's of Alzheimers Disease

ABCs of Alzheimer's Disease: a Shared Reality by Me and My Shadow is a story of Bruce and Ethel's Alzheimer's disease (AD) journey, along with a history of AD from autopsies to PET scan research, including technology and genetic discoveries. The book is a realistic, short, comprehensive, evidence-based, description of Alzheimer's disease (AD). It describes AD research, including clinical trials, a simplified understanding of the brain, and the experiences of patient/caregiver persistence and journey as well as hope for

Comprehensive Medicinal Chemistry III

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  • Publisher : Elsevier
  • Release Date : 2017-06-03
  • ISBN : 9780128032015
DOWNLOAD BOOKComprehensive Medicinal Chemistry III

Comprehensive Medicinal Chemistry III provides a contemporary and forward-looking critical analysis and summary of recent developments, emerging trends, and recently identified new areas where medicinal chemistry is having an impact. The discipline of medicinal chemistry continues to evolve as it adapts to new opportunities and strives to solve new challenges. These include drug targeting, biomolecular therapeutics, development of chemical biology tools, data collection and analysis, in silico models as predictors for biological properties, identification and validation of new targets, approaches

Differential diagnosis of dementing diseases

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  • Publisher : Unknown
  • Release Date : 1987
  • ISBN : MINN:31951D01951424R
DOWNLOAD BOOKDifferential diagnosis of dementing diseases

The End of Alzheimer's

The End of Alzheimer's
  • Author : Dale Bredesen
  • Publisher : Penguin
  • Release Date : 2017-08-22
  • ISBN : 9780735216228
DOWNLOAD BOOKThe End of Alzheimer's

The instant New York Times and Wall Street Journal bestseller A groundbreaking plan to prevent and reverse Alzheimer’s Disease that fundamentally changes how we understand cognitive decline. Everyone knows someone who has survived cancer, but until now no one knows anyone who has survived Alzheimer's Disease. In this paradigm shifting book, Dale Bredesen, MD, offers real hope to anyone looking to prevent and even reverse Alzheimer's Disease and cognitive decline. Revealing that AD is not one condition, as it

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  • Publisher : Academic Press
  • Release Date : 2016-05-27
  • ISBN : 9780128021644
DOWNLOAD BOOKDeveloping Therapeutics for Alzheimer's Disease

Developing Therapeutics for Alzheimer's Disease: Progress and Challenges provides a thorough overview of the latest advances toward the development of therapeutics for Alzheimer’s disease, along with the major hurdles that still must be overcome and potential solutions to these problems. Despite the lack of progress toward developing therapeutics that can slow or stop the progression of this disease, important discoveries have been made and many promising approaches are advancing in preclinical studies and clinical trials. This book outlines the

Polypharmacology

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  • Publisher : Springer Nature
  • Release Date : 2022-08-01
  • ISBN : 9783031049989
DOWNLOAD BOOKPolypharmacology

There is a growing interest in unmet needs for the development of a new discipline in drug discovery and in university education on polypharmacology. However, there has not been a book with the comprehensive compilation of basic knowledge and advanced methodology that is needed. This book aims to meet the needs making Polypharmacology a new sub-discipline of Pharmacology, not only being a hot area of pharmacological research and education but also a new paradigm for drug discovery. It contains the

Immunonutrition

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  • Author : Bharat B. Aggarwal,David Heber
  • Publisher : CRC Press
  • Release Date : 2014-03-17
  • ISBN : 9781466503861
DOWNLOAD BOOKImmunonutrition

The interaction of immune function and nutrition underlies the low-grade chronic inflammation involved in the etiology of many common obesity-associated and age-related chronic disease conditions. This close interaction is the genesis of the term immunonutrition, which represents a new interdisciplinary field of nutritional and medical research. Immunonutrition: Interactions of Diet, Genetics, and Inflammation introduces the breadth of this field, which implicates nutrition in both immune function and in the etiology, prevention, and treatment of common diseases influenced by inflammation and

Animal Experimentation

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  • Author : Kathrin Herrmann,Kimberley Jayne
  • Publisher : Human-Animal Studies
  • Release Date : 2019
  • ISBN : 9004356185
DOWNLOAD BOOKAnimal Experimentation

Animal Experimentation: Working Towards a Paradigm Change critically appraises current animal use in science and discusses ways in which we can contribute to a paradigm change towards human-biology based approaches.

Oxford Textbook of Public Mental Health

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  • Publisher : Oxford University Press
  • Release Date : 2018-09-13
  • ISBN : 9780192511409
DOWNLOAD BOOKOxford Textbook of Public Mental Health

Prevention of mental illness and mental health promotion have often been ignored in the past, both in undergraduate and postgraduate curricula. Recently, however, there has been a clear shift towards public mental health, as a result of increasing scientific evidence that both these actions have a serious potential to reduce the onset of illness and subsequent burden as a result of mental illness and related social, economic and political costs. A clear distinction between prevention of mental illness and mental

Evidence-based Clinical Practice Guideline for Deprescribing Cholinesterase Inhibitors and Memantine

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  • Author : E. Reeve,B. Farrell,W. Thompson,N. Herrmann,I. Sketris,P. Magin,L. Chenoweth,M. Gorman,L. Quirke,G. Bethune,F. Forbes,S. Hilmer
  • Publisher : Unknown
  • Release Date : 2018-02-06
  • ISBN : 0648265811
DOWNLOAD BOOKEvidence-based Clinical Practice Guideline for Deprescribing Cholinesterase Inhibitors and Memantine

The End of Alzheimer's Program

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  • Author : Dale Bredesen
  • Publisher : Penguin
  • Release Date : 2020-08-18
  • ISBN : 9780525538509
DOWNLOAD BOOKThe End of Alzheimer's Program

The instant New York Times bestseller The New York Times Best Selling author of The End of Alzheimer's lays out a specific plan to help everyone prevent and reverse cognitive decline or simply maximize brainpower. In The End of Alzheimer's Dale Bredesen laid out the science behind his revolutionary new program that is the first to both prevent and reverse symptoms of Alzheimer's disease. Now he lays out the detailed program he uses with his own patients. Accessible and detailed,

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  • Publisher : BoD – Books on Demand
  • Release Date : 2021-01-20
  • ISBN : 9781838801496
DOWNLOAD BOOKNeurodegenerative Diseases

Neurodegenerative diseases represent a very large group of heterogeneous disorders affecting specific subtypes of neurons in the brain. This book contributes insight both to the awareness of the brain and its neurodegenerative states. The chapters present current knowledge regarding genetics, molecular mechanisms, and new therapeutic strategies against neurodegenerative disorders. The book is intended to serve as a source to aid clinicians and researchers in the field, and also life science readers to increase their understanding and awareness of the clinical

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  • Author : Atanu Bhattacharjee,Akula Ramakrishna,M. Obulesu
  • Publisher : CRC Press
  • Release Date : 2020-10-26
  • ISBN : 9781000171389
DOWNLOAD BOOKPhytomedicine and Alzheimer’s Disease

Alzheimer's disease, one of the most rapidly growing neurodegenerative disorders, is characterized by a progressive loss of memory. Despite several advances in the field of medical therapeutics, a viable treatment for Alzheimer's disease would be of great importance. Medicinal plants represent a largely untapped reservoir of natural medicines and potential sources of anti-Alzheimer’s drugs. The structural diversity of their phytoconstituents makes these plants a valuable source of novel lead compounds in the quest for drugs to treat Alzheimer's disease.

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  • ISBN : 9782889747139
DOWNLOAD BOOKNeuroimaging Biomarkers and Cognition in Alzheimer’s disease Spectrum